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Principal Scientist

2 months ago


Marlborough, Massachusetts, United States Sartorius North America Full time
About the Role

We are seeking a highly skilled Principal Scientist to join our Emerging Therapies Services team at Sartorius North America. As a key member of our Corporate Research Group, you will play a critical role in the design, development, and optimization of iPSC engineering and manufacturing processes.

Key Responsibilities
  • Design and optimize protocols for the differentiation of iPSCs into specific cell types using cutting-edge techniques.
  • Lead cross-functional teams to scale iPSC expansion and differentiation from benchtop to production scale bioreactors.
  • Develop and write process development proposals, conduct hands-on laboratory work to optimize and troubleshoot upstream and downstream manufacturing processes.
  • Analyze and interpret data, ensuring clear documentation of methodologies and outcomes.
  • Prepare detailed reports and presentations for internal and external partners to communicate progress in line with project schedules.
  • Assist in mentoring and training junior team members and coordinating the day-to-day operations.
  • Lead technology transfer activities to internal and external collaborators.
  • Support marketing efforts by writing technical briefs, application notes, and peer-reviewed publications.
Requirements
  • Extensive expertise in generating, differentiating, expanding and characterizing pluripotent cells and their derivatives.
  • Expertise in differentiating pluripotent cells into multiple clinically relevant lineages in planar and bioreactor systems.
  • Hands-on experience with multiplexed genome editing technologies and single cell cloning.
  • Knowledge of GxPs, experience in process development or GMP operation.
  • Demonstrated ability to design, plan, and implement pluripotent cell differentiation protocols.
What We Offer
  • Strong analytical and mathematical ability.
  • Ability to work independently and constructively in a team environment.
  • Strong personal initiative and results-oriented.
  • Strong troubleshooting skills.
  • Strong written and verbal communication skills.
About Sartorius North America

Sartorius is a global life science company, listed on the German DAX and TecDAX, offering a wide range of benefits, including:

  • Personal and Professional Development: mentoring, leadership programs, LinkedIn Learning, internal seminar offerings.
  • Worklife Balance: paid vacation, sick time, corporate holidays and community service day; flexible work schedules.
  • Welcoming Culture: mutual support, team spirit and international collaboration.
  • Health & Well Being: wide selection of health and well-being support.
  • Intelligent Working Environment: working in smart buildings with the latest technology and equipment.
Equal Opportunity Employer

Sartorius is an Equal Opportunity/Affirmative Action employer and will consider all qualified applicants for employment without regard to race, color, religion, gender, sexual orientation, gender identity, national origin, age, protected veteran status, or disability status.