Director, Bioanalytical DMPK
1 month ago
Mersana is growing and has an exciting new opportunity for a Director, Bioanalytical DMPK to join our team.As the Director, Bioanalytical DMPK, you will have the opportunity to lead a team of ligand binding assay (LBA) and mass spectrometry laboratory scientists in developing bioanalytical assays for new and existing ADC programs for preclinical pharmacology, DMPK and Toxicology studies.You will oversee the development, technology transfer and oversight of vendors running bioanalytical assays to support non GLP and GLP analysis of preclinical studies.You will be able to use your knowledge and expertise in all analytical methods of in vitro and in vivo drug metabolism and pharmacokinetics, and serve as a DMPK subject matter expert on project teams from research through development.Design non-clinical ADME studies for mass balance and metabolite characterization and identification.12 or more years post-graduate experience in relevant drug metabolism, bioanalytical methods of analysis and pharmacokinetics.Expertise in various aspects of ADME and PK for small molecules or biologics.Track record in bioanalysis of small molecules or biologics with deep expertise in bioanalytical LC-MS platforms to support PK/TK, efficacy in preclinical space.
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Executive Director, DMPK
4 weeks ago
Cambridge, Massachusetts, United States Nimbus Therapeutics Full timeNimbus has an outstanding opportunity for an exceptional Executive Director, DMPK to join our team. This role will serve as the function head, applying subject matter expertise in absorption, distribution, metabolism, and excretion (ADME), pharmacokinetics, and pharmacodynamics, along with effective team management skills, to drive the strategy and execution...
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Director, Medicinal Chemistry
1 month ago
Cambridge, Massachusetts, United States Foghorntx Full timeThe Director, Medicinal Chemistry will devise and implement medicinal chemistry strategies to advance chemical matter through all stages of drug discovery, from hit ID to DC nomination.Plan, prioritize and implement synthetic and medicinal chemistry strategies to achieve project goalsCollaborate with functional leads – e.g., computational chemistry,...
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Associate Director
1 month ago
Cambridge, Massachusetts, United States Cullinan Oncology, Inc Full timeAnchored in a deep understanding of immuno-oncology and translational cancer medicine, we leverage our scientific excellence in small molecules and biologics to create differentiated ideas, identify unique targets, and select the optimal modality to develop transformative therapeutics across cancer indications.A successful incumbent would help integrate...
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Scientist, DMPK
5 days ago
Cambridge, Massachusetts, United States Biogen Full timeJob Description About This Role Biogen is seeking a highly motivated scientist with excellent knowledge and experience in LC-MS/MS bioanalysis to join the Drug Metabolism and Pharmacokinetics (DMPK) department. The candidate will be responsible for bioanalytical support of discovery and development programs, including small molecule compounds and...
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Head, Clinical Pharmacology
6 days ago
Cambridge, United States Leap Therapeutics Full time**Head, Clinical Pharmacology**: **Company Summary**: **General Responsibilities**: ***The Head of Clinical Pharmacology will be responsible for developing and executing the clinical and non-clinical pharmacology strategies for compounds from the pre-clinical stage through first-in-human and into late-stage clinical development. They will support programs by...
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Associate Director, Pharmacokinetic Sciences
7 hours ago
Cambridge, United States Novartis Full time**Summary**: L1-Hybrid About the role: This position will be on-site with preference for Cambridge, MA and will not have the ability to be located remotely. In the role of Associate Director in PKS you will provide ADME /PK/PKPD project support in the Cardiovascular and Metabolic Therapeutic Area by contributing to the transition of drug projects from...
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Associate Director, Pk Sciences
7 hours ago
Cambridge, United States Novartis Full time**About the Role**: About the role: Position will be on-site in Cambridge, MA and will not have the ability to be located remotely. In the role of Associate Director in PK Sciences you will provide ADME /PK/PKPD project support to the Neuroscience Therapeutic Area contributing to projects from Discovery to IND filing and First-in-Human studies and beyond. In...
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Director, Medicinal Chemistry
2 weeks ago
Cambridge, United States Foghorn Therapeutics Inc. Full timeOur Culture: Why work with us? At Foghorn Therapeutics, we believe in "People First, Mission Always." We put "People First" because we know our people are the key to everything we will accomplish. We value the diversity of background, ideas, perspectives and experiences that our team members bring to Foghorn Therapeutics - demonstrated by our community...
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Associate Director
1 day ago
Cambridge, United States Avalyn Pharma Inc Full timeJob DescriptionJob DescriptionAssociate Director / Director, Product Development Company Overview:Avalyn Pharma is developing innovative, inhaled therapies to target the lungs for treatment of rare respiratory diseases, including idiopathic pulmonary fibrosis (IPF) and progressive pulmonary fibrosis (PPF). Avalyn completed an oversubscribed $175M Series C...
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Biomarker Study Manager, Senior Manager
2 weeks ago
Cambridge, Massachusetts, United States Biogen Full timeJob Description About This Role This role is responsible for clinical study bioanalytical and biomarker operations management. The bioanalytical and biomarkers study manger is a member of the clinical study team and will contribute to study start up, sample testing, data delivery and CRO management as it relates directly to supporting the PK, ADA and...
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Director, Clinical Operations
2 weeks ago
Cambridge, United States Boston Pharmaceuticals Full timeCompany Overview Boston Pharmaceuticals is a clinical-stage biopharmaceutical company. We are developing highly engineered targeted therapies for patients with serious liver diseases. Our lead investigational program, BOS-580, is a long-acting once-monthly FGF21 analogue being studied in a Phase 2 clinical trial for metabolic dysfunction-associated...
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Associate Director Director Product Development
22 hours ago
Cambridge, United States Avalyn Pharma Inc Full timeBenefits: 401(k) matching Company parties Competitive salary Dental insurance Health insurance Opportunity for advancement Paid time off Parental leave Stock options plan Vision insurance Wellness resources Associate Director / Director, Product Development Company Overview: Avalyn Pharma is developing innovative, inhaled therapies to target the lungs for...
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Associate Director
2 days ago
Cambridge, United States Avalyn Pharma Inc Full timeJob DescriptionJob DescriptionBenefits:401(k) matchingCompany partiesCompetitive salaryDental insuranceHealth insuranceOpportunity for advancementPaid time offParental leaveStock options planVision insuranceWellness resources Associate Director / Director, Product Development Company Overview:Avalyn Pharma is developing innovative, inhaled therapies to...
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Director, Scientific Governance Pks
7 hours ago
Cambridge, United States Novartis Full time**Summary**: About the role: This position will be located in Cambridge, MA and will not have the ability to be located remotely. #LI-Hybrid As the Director, Scientific Governance PKS you will provide regulatory expertise and scientific leadership in the drug development process of Biotherapeutics including Cell and Gene (C&G) therapies, in close...
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Director, Clinical Operations
2 weeks ago
Cambridge, United States Boston Pharmaceuticals Full timeCompany OverviewBoston Pharmaceuticals is a clinical-stage biopharmaceutical company. We are developing highly engineered targeted therapies for patients with serious liver diseases. Our lead investigational program, BOS-580, is a long-acting once-monthly FGF21 analogue being studied in a Phase 2 clinical trial for metabolic dysfunction-associated...