Associate Director, Pharmacokinetic Sciences

2 weeks ago

Cambridge, United States Novartis Full time

**Summary**:
L1-Hybrid About the role: This position will be on-site with preference for Cambridge, MA and will not have the ability to be located remotely. In the role of Associate Director in PKS you will provide ADME /PK/PKPD project support in the Cardiovascular and Metabolic Therapeutic Area by contributing to the transition of drug projects from discovery to First-in-Human studies and further clinical development. In this unique role you will collaborate and partner with PKS functions including in vitro and in vivo ADME, biotransformation, bioanalytics and modeling & simulation (M&S) and represent the PKS organization within project teams.

**About the Role**:
Key responsibilities:

- Provide matrixed leadership across the organization to align and influence across the cross-functional team to identify and mitigate key project issues related to the PKS discipline (e.g., PK, PK/PD, metabolism and clinical pharmacology).
- Be responsible for the PK, PK/PD and M&S component of study protocols, reports, project summaries and development plans, and author pharmacokinetic/clinical pharmacology/biopharmaceutics sections of IND/IMPDs and NDAs within agreed timelines and which meet regulatory requirements as well as prepare appropriate responses to Health Authority questions (globally).
- Oversee or perform PK and PK/PD analyses using a variety of tools and approaches and integrate, interpret and report data to project teams and other customers. Our organization further offers the opportunity to seamlessly gain exposure to different stages of development, different drug modalities and cross-train in multiple indications.

Novartis EVP Manifesto.mp4
- Essential Requirements:
- Ph.D. or Pharm.D. with relevant experience in clinical pharmacology, drug metabolism and pharmacokinetics or a related biologic background.
- A minimum of four to six plus years in early/late drug development including 2 plus years of experience in a lead role overseeing ADME/DMPK strategy of drug development, clinical protocol and report writing, clinical pharmacology plans, modeling strategies, Health Authority interactions.
- Extensive and in-depth knowledge of pharmacokinetics including, drug metabolism and PK/PD evaluation, experience in working in project teams (preferably global) as well as sound awareness of recent developments in drug development and regulatory sciences.
- Hands-on project experience with low molecular weight and biologics is required with oligonucleotide experience optional in drug development.
- Proven record as leader with good negotiation, organizational and project management skills.
- Strong coaching and mentoring skills desired.

Commitment to Diversity and Inclusion:
Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Novartis Compensation and Benefit Summary: The pay range for this position at commencement of employment is expected to be between $151,200 - $226,800/year; however, while salary ranges are effective from 1/1/24 through 12/31/24, fluctuations in the job market may necessitate adjustments to pay ranges during this period. Further, final pay determinations will depend on various factors, including, but not limited to geographical location, experience level, knowledge, skills, and abilities. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Division

Biomedical Research

Business Unit

Pharma Research

Location

USA

Site

Cambridge (USA)

Company / Legal Entity

U175 (FCRS = US175) Novartis Institutes for BioMedical Research, Inc.

Functional Area

Research & Development

Job Type

Full time

Employment Type

Regular

Shift Work

No

  • Associate Director, Pk Sciences

    2 weeks ago

    Cambridge, United States Novartis Full time

    **About the Role**: About the role: Position will be on-site in Cambridge, MA and will not have the ability to be located remotely. In the role of Associate Director in PK Sciences you will provide ADME /PK/PKPD project support to the Neuroscience Therapeutic Area contributing to projects from Discovery to IND filing and First-in-Human studies and beyond. In...

  • Senior Scientist, Pharmacokinetics, Dynamics and Metabolism

    6 days ago

    Cambridge, United States Pfizer Full time

    Why Patients Need You Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or...

  • Associate Director PKDM

    2 weeks ago

    Cambridge, United States Strivector Full time

    THE EMPLOYER Take your career up a few notches with this an innovative global healthcare company, who chase the miracles of science to improve peoples lives. THE JOB Responsibilities This is a Associate Director PKDM position and requires someone who is a dynamic individual to serve as a PK/PD expert participating in multidisciplinary teams for clinical...

  • Associate Director PKDM

    2 weeks ago

    Cambridge, United States Strivector Full time

    THE EMPLOYER Take your career up a few notches with this an innovative global healthcare company, who chase the miracles of science to improve people s lives. THE JOB This is a Associate Director PKDM position and requires someone who is a dynamic individual to serve as a PK/PD expert participating in multidisciplinary teams for clinical phase development...

  • Associate Director Pharmacology

    2 weeks ago

    Cambridge, United States Greenfield Source Full time

    This is an Associate Director level Pharmacokinetics, Dynamics, and Metabolism (PKDM) role. This department contributes to the safe and effective therapeutic treatment of each patient by applying appropriate pharmacokinetic (PK) and pharmacodynamic (PD) principles to drug development and accelerating the process, where possible. PKDM generates, integrates,...

  • Associate Director Pharmacology

    3 weeks ago

    Cambridge, United States Greenfield Source Full time

    This is an Associate Director level Pharmacokinetics, Dynamics, and Metabolism (PKDM) role. This department contributes to the safe and effective therapeutic treatment of each patient by applying appropriate pharmacokinetic (PK) and pharmacodynamic (PD) principles to drug development and accelerating the process, where possible. PKDM generates, integrates,...

  • Associate Director Pharmacology

    3 weeks ago

    Cambridge, United States Greenfield Source Full time

    This is an Associate Director level Pharmacokinetics, Dynamics, and Metabolism (PKDM) role. This department contributes to the safe and effective therapeutic treatment of each patient by applying appropriate pharmacokinetic (PK) and pharmacodynamic (PD) principles to drug development and accelerating the process, where possible. PKDM generates, integrates,...

  • Associate Director, Clinical Pharmacology

    17 hours ago

    Cambridge, United States Bicycle Therapeutics Limited Full time

    Company Description Bicycle Therapeutics (NASDAQ: BCYC) is a clinical-stage biopharmaceutical company developing a novel class of medicines. Our pipeline includes Bicycle Toxin Conjugates as well as fully synthetic Bicycle systemic immune cell agonists and Bicycle tumor-targeted immune cell agonists (Bicycle TICAs) focused on oncology indications with high...

  • Associate Director, Clinical Pharmacology

    2 days ago

    Cambridge, United States Bicycle Therapeutics Limited Full time

    Company Description Bicycle Therapeutics (NASDAQ: BCYC) is a clinical-stage biopharmaceutical company developing a novel class of medicines. Our pipeline includes Bicycle Toxin Conjugates® as well as fully synthetic Bicycle® systemic immune cell agonists and Bicycle tumor-targeted immune cell agonists (Bicycle TICAs) focused on oncology indications with...

  • Associate Director, Clinical Pharmacology

    6 days ago

    Cambridge, United States Bicycle Therapeutics Full time

    Job DescriptionJob DescriptionCompany DescriptionBicycle Therapeutics (NASDAQ: BCYC) is a clinical-stage biopharmaceutical company developing a novel class of medicines. Our pipeline includes Bicycle Toxin Conjugates® as well as fully synthetic Bicycle® systemic immune cell agonists and Bicycle tumor-targeted immune cell agonists (Bicycle TICAs) focused on...

  • Associate Director, Clinical Pharmacology

    19 hours ago

    Cambridge, United States Bicycle Therapeutics Full time

    Job DescriptionJob DescriptionCompany DescriptionBicycle Therapeutics (NASDAQ: BCYC) is a clinical-stage biopharmaceutical company developing a novel class of medicines. Our pipeline includes Bicycle Toxin Conjugates® as well as fully synthetic Bicycle® systemic immune cell agonists and Bicycle tumor-targeted immune cell agonists (Bicycle TICAs) focused on...

  • Associate Director, Clinical Pharmacology

    6 days ago

    Cambridge, United States Bicycle Therapeutics Full time

    Company DescriptionBicycle Therapeutics (NASDAQ: BCYC) is a clinical-stage biopharmaceutical company developing a novel class of medicines. Our pipeline includes Bicycle Toxin Conjugates® as well as fully synthetic Bicycle® systemic immune cell agonists and Bicycle tumor-targeted immune cell agonists (Bicycle TICAs) focused on oncology indications with...

  • Associate Director, Clinical Pharmacology

    6 days ago

    Cambridge, United States Bicycle Therapeutics Full time

    Bicycle Therapeutics (NASDAQ: BCYC) is a clinical-stage biopharmaceutical company developing a novel class of medicines. Our pipeline includes Bicycle Toxin Conjugates® as well as fully synthetic Bicycle® systemic immune cell agonists and Bicycle tumor-targeted immune cell agonists (Bicycle TICAs) focused on oncology indications with high unmet medical...

  • Executive Director, DMPK

    1 month ago

    Cambridge, Massachusetts, United States Nimbus Therapeutics Full time

    Nimbus has an outstanding opportunity for an exceptional Executive Director, DMPK to join our team. This role will serve as the function head, applying subject matter expertise in absorption, distribution, metabolism, and excretion (ADME), pharmacokinetics, and pharmacodynamics, along with effective team management skills, to drive the strategy and execution...

  • Associate Director, Biology

    3 weeks ago

    Cambridge, Massachusetts, United States Nimbus Therapeutics Full time

    Nimbus has an outstanding opportunity for an exceptional Associate Director of Biology to join our team. The person in this role will take on a variety of responsibilities contributing to Nimbus' current, ongoing projects and strategy, as well as evaluation of potential new targets. This role will primarily support Nimbus' Immunology pipeline and will report...

  • Associate Director, Biology

    3 weeks ago

    Cambridge, United States Nimbus Therapeutics Full time

    Nimbus has an outstanding opportunity for an exceptional Associate Director of Biology to join our team. The person in this role will take on a variety of responsibilities contributing to Nimbus’ current, ongoing projects and strategy, as well as evaluation of potential new targets. This role will primarily support Nimbus' Immunology pipeline and will...

  • Deputy Director of Science and Technology

    4 days ago

    Cambridge, United States Massachusetts Institute of Technology Full time

    Deputy Director of Science and TechnologyJob Number: 24007Functional Area: Research - OtherDepartment: MIT Energy InitiativeSchool Area: VP ResearchEmployment Type: Full-TimeEmployment Category: ExemptVisa Sponsorship Available: NoSchedule: Job Description DEPUTY DIRECTOR OF SCIENCE AND TECHNOLOGY, MIT Energy Initiative (MITEI), to join MIT’s hub for low...

  • Deputy Director of Science and Technology

    4 days ago

    Cambridge, Massachusetts, United States Massachusetts Institute of Technology Full time

    Deputy Director of Science and TechnologyJob Number: 24007Functional Area: Research - OtherDepartment: MIT Energy InitiativeSchool Area: VP ResearchEmployment Type: Full-TimeEmployment Category: ExemptVisa Sponsorship Available: NoSchedule:Job DescriptionDEPUTY DIRECTOR OF SCIENCE AND TECHNOLOGY, MIT Energy Initiative (MITEI), to join MIT's hub for low and...

  • Director, Clinical Science

    4 weeks ago

    Cambridge, United States Foghorn Therapeutics Inc. Full time

    Our Culture: Why work with us? At Foghorn Therapeutics, we believe in "People First, Mission Always." We put "People First" because we know our people are the key to everything we will accomplish. We value the diversity of background, ideas, perspectives and experiences that our team members bring to Foghorn Therapeutics - demonstrated by our community...

  • Deputy Director of Science and Technology

    3 weeks ago

    Cambridge, Massachusetts, United States Massachusetts Institute of Technology (MIT) Full time

    Job Description DEPUTY DIRECTOR OF SCIENCE AND TECHNOLOGY , MIT Energy Initiative (MITEI) , to join MIT's hub for low and no-carbon energy research, education, and outreach. Will act as second in command for this dynamic organization on topics related to creating a clean, affordable, and equitable energy system. Responsibilities include engaging with MITEI...