Associate Scientist II, Biological Research

1 month ago

Irvine, Kentucky, United States AbbVie Full time

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us Follow @abbvie onTwitter,Facebook,Instagram,YouTubeandLinkedIn.
Job Description

The Toxin Innovation Group at AbbVie seeks a highly skilled and experienced associate scientist II with the experience in genetic engineering of microbial organisms. The successful candidate will play an integral role in supporting our efforts to design, engineer and optimize microbial strains for both aesthetic and therapeutic applications, driving the advancement of our product pipeline and contributing to the overall success of the company.

The ideal candidate will have training on designing and implementing molecular cloning techniques for the modification of microbial genomes to achieve specific phenotypic traits, preferably with anaerobic bacteria. The candidate will be able to maintain the laboratory environment and ELN documentation in compliance with regulatory and company expectations.

Key responsibilities:

Design and execute experiments to engineer microbial strains for enhanced production of target molecules or proteins.Learn and apply genetic engineering tools and techniques for microbial strain engineering.Conduct molecular biology techniques, including DNA manipulation, cloning, and gene expression analysis.Perform microbial strain characterization, including growth kinetics and product analysis.Collaborate with other team members to identify and prioritize target molecules and develop strategies for strain improvement.Analyze and interpret experimental data, prepare technical reports, and present findings to internal team members.Maintain accurate and detailed laboratory records, including experimental protocols, data, and observations.Ensure compliance with safety guidelines and maintain a clean and organized laboratory environment.
Qualifications
Industrial or academia experience in microbial strain engineering.Direct experience with molecular biology techniques, such as DNA extraction, PCR, cloning, and gene expression analysis.Familiar with genome editing techniques, including CRISPR/Cas9, homologous recombination, and gene knockout.Experience with cultivation techniques and screening methods for microbial strain characterization.Familiarity with microbial fermentation processes and downstream processing is a plus.Knowledge of NGS library preparation workflow is a plus.Excellent problem-solving skills and ability to work both independently and collaboratively.A collaborative mindset and the ability to work effectively within interdisciplinary research teams.Effective communication and presentation skills, with the ability to collaborate and work in a team-oriented environment.Education & Experience:Masters in microbiology, Molecular Biology, Bioengineering, Synthetic Biology or equivalent field or Bachelors Degree with 3+ years of related work;Industrial experience is preferred in biotech or pharma discovery research
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: The compensation range described below is the range of possible base pay compensation that the Company believes ingood faith it will pay for this role at the time of this posting based on the job grade for this position. Individualcompensation paid within this range will depend on many factors including geographic location, and we may ultimatelypay more or less than the posted range. This range may be modified in the future. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/visioninsurance and 401(k) to eligible employees. This job is eligible to participate in our short-term incentive programs. Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, and determinable.The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefitsthat are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent with applicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVies policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status. US & Puerto Rico only - to learn more, visit

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