Scientist, Bioanalytical

1 month ago

San Diego, California, United States Neurocrine Biosciences Full time

in collaboration with AbbVieThe Bioanalytical Scientist, as part of the DMPK, Preclinical Development team, will develop and perform assays to quantify large molecule therapeutics in biological fluids and tissues.The qualified individual will be responsible for the implementation of various types of immunoassays (e.g., ELISA and electrochemiluminescence), immunogenicity or quantitative PCR assays to answer key questions related to pharmacokinetics, pharmacodynamics, and biodistribution.Under the mentorship of a supervisor, this individual will develop and optimize quantitative non-regulated bioanalytical assays.Perform sample analysis to support bioanalysis efforts for preclinical studies, including pharmacokinetics, pharmacodynamics, immunogenicity, and biological activityGenerate and characterize critical reagents to support assay development and assay life cycle maintenance (e.g., Biotinylation)Degree in biology, chemistry, or related science, preferably with experience in a bioanalytical laboratorySome background in bioanalytical job-relevant core competency (immunoassays such as ELISA, handling of a variety of biological matrices such as serum and plasma, automation, method development/validation GLP studies, biomarker analysis)

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