Research Scientist Protein Purification and Qualification

1 month ago

Foster City, California, United States Gilead Sciences, Inc. Full time
Research Scientist Protein Purification and Qualification
United States - California - Foster City

Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead's therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.

Making an impact on a global scale
Inclusion is one of the company's five core values. That's because we know that we are stronger and more innovative at Gilead when we are informed by a diverse set of backgrounds, experiences and points of view. Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide.

When you join Gilead, you join our mission to change the world by enabling people to live healthier and more fulfilling lives. Come join a mission-driven bio-pharmaceutical organization that values inclusion and diversity, has a strong portfolio of products, and is constantly #CreatingPossible

For Current Gilead Employees and Contractors:

Please log onto your Internal Career Site to apply for this job.

At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer - working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world's biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.

Every member of Gilead's team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we're looking for the next wave of passionate and ambitious people ready to make a direct impact.

We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.

Job Description

Gilead Sciences Protein Therapeutics Department has an exciting opportunity for highly motivated Research Scientist to join the Protein Science group. In this position, the candidate will support diverse research project teams in generation and analytical characterization of biologics molecules. He/she should have hands-on experience and in-depth knowledge of protein purification and qualification. This person will work in collaboration with research project teams to generate potential therapeutic proteins and surrogate tool molecules, aiding in the selection of lead candidates including bispecific antibodies, immunocytokines, and many other novel and complex biologics.

Responsibilities:
Execute protein purification and qualification protocols, and perform troubleshooting when neededContinuously adopt state of the art technologies to improve efficiency and/or expand capability for protein purification and qualificationCollaborate with therapeutic area biologists to generate proteins and advance project goals in support of large molecule therapeutic programsServe as a technical expert in research project teams, and may serve as a core team member representing Protein TherapeuticsMentor and may manage junior staff

Required skills
Detailed scientific knowledge of protein scienceSkilled in programing and use of AKTA Avant/Pure or BioRad NGC for protein purificationExtensive experience in purification of biologics molecules using techniques including affinity (Protein A/G/L, Capture Select affinity resins, Ni-NTA, etc), ion exchange, size exclusion, hydrophobic interaction chromatography, mixed-mode chromatographyExperienced in various protein analytical techniques such as HPLC or UHPLC, SDS-PAGE or CE-SDS, Endosafe, SEC-MALSWorking knowledge in construct design for therapeutics proteins and surrogate tool moleculesStrong analytical, communication, and organizational skills

Nice to have skills
Experience in automated liquid handling systems for protein purification (e.g., Tecan) is a strong plusExperience in LC-MS analysis of biologics sample is highly desired

The salary range for this position is: $143, $185, Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.

For additional benefits information, visit:

* Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.

For jobs in the United States:

As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact for assistance.

For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster.

NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT
YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT

PAY TRANSPARENCY NONDISCRIMINATION PROVISION

Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.

Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.

For Current Gilead Employees and Contractors:

Please log onto your Internal Career Site to apply for this job.

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