Senior Research Analyst
2 weeks ago
Seeking Biochemistry candidate with hands-on experience in methods such as size exclusion HPLC, SDS-PAGE, DSF, ELISA and/or Octet/SPR. The selected candidate will work at the bench to QC TCR bispecifics and MHC proteins, conduct stability/developability assessments to prioritize therapeutic leads, and develop robust assays for tech transfer to manufacturing partners. This incumbent will be responsible for developing SOPs, generating biochemical and biophysical data, data analysis and presenting data to their manager and to the team in an effective and timely manner. Interested candidates should have strong organizational, interpersonal, verbal, and written communication skills that will enable them to integrate with our highly cross-functional team.
Key Responsibilities
- Analytical and biophysical QC of protein batches (analytical SEC, PAGE, DSF, Octet/SPR, ELISA).
- Develop and document robust analytical assays for tech transfer to manufacturing partners.
- Conduct comparability, developability and accelerated stability assessments of lead therapeutic molecules.
- Capture primary data, establish and maintain SOPs, and document work as required in Electronic Laboratory Notebook (ELN), maintaining up to date records.
- Present data routinely to the Protein Sciences group and other multidisciplinary groups.
Qualifications/Experience
- BS/MS in Biochemistry, Biology, Bioengineering, Immunology, or a similar field.
- 2+ years of academic or biotech/pharma laboratory experience.
- Experience with HPLC systems and with biochemical assays such as ELISA, SDS-PAGE and DSF.
- Experience with Octet, SPR or flow cytometry a plus.
- Strong organizational and communication skills along with excellent attention to details.
- Enjoys working in a collaborative, fast-paced and quickly changing environment.
Salary Range: $80-95K/yr
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