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Senior Research Associate- Assay Technology
2 months ago
611289
Our client, a leading Biotechnology company in Redwood City, CA, is looking for a Senior Research Associate, Assay Technology to help the Discovery Sciences team accelerate our search for new oncology therapeutics.
Required Skills:
- Bachelor’s degree with 3-5 years of experience or Master’s degree with 2-3 years of experience in biochemistry, biophysics, biotechnology, or related field
- Hands-on protein biochemistry experience (e.g., characterizing and analyzing protein-ligand or protein-protein interactions)
- Experience with biochemical/biophysical assay development, validation, and troubleshooting
- Proficiency in execution of in vitro biochemical and biophysical assays suitable for the discovery, validation, or mechanistic characterization of target molecules (ITC, SPR/BLI, TR-FRET, fluorescence polarization, etc.)
- Familiarity with data processing and visualization tools for data analysis and figure generation (e.g., R, Vortex, GraphPad Prism, Genedata Screener, etc).
Responsibilities:
- Design and execution of lead discovery screening methods and experiments to identify compound hits and advance them through hit-to-lead and lead optimization stages
- Collaborate within Discovery Science and cross-functionally with Compound Management, Structural Biology, and Biology/Chemistry teams to develop and implement biochemical and biophysical assays for hit identification and lead optimization, evaluating compound potency, selectivity, and mechanism of action, biophysical and biochemical assay development.
- Develop, characterize, and execute novel biochemical and biophysical assays to support screening and preclinical development.
- Communicate scientific progress effectively to Discovery Sciences team and facilitate project execution within established timelines
- Generate, manage, evaluate, and maintain critical data in an organized manner and disseminate data broadly to relevant departments
- Maintain detailed electronic lab notebook entries, draft protocols for experiments, assay data summaries, and manage reagent stocks
***Compensation within this range will be commensurate with level of experience***