Research Associate or Senior Research Associate, Therapeutics
2 months ago
About Earli
Earli exists to make cancer a benign experience. Earli does that by turning cancers against themselves: genetically forcing them to reveal themselves early, and then kill themselves – precisely and clearly distinguishable from benign lesions at early stages. Based on original technology from Stanford's renowned Gambhir lab, Earli designs genetic constructs that are injected intravenously that turn cancer cells against themselves. These programmable synthetic promoter-reporter sequences "flip on" like light switches only in dysregulated cancer cells and turn them into "factories." The cancer is forced to produce either an epitope "docking station" for imaging agents, or a cytokine for immune system activation against the tumor. Thus, Earli's platform enables immediate diagnosis and treatment of early cancers, rather than long-term observation that can lead to deadly metastatic recurrence.
Earli's synthetic target expression platform has evolved over five years of deep bioengineering. The system can now detect broad ranges of patient mutations, distinguish between malignant and benign lesions, and offer independence from often elusive natural biomarkers.
Earli has raised $82m in three rounds from investors including Andreessen Horowitz, Khosla Ventures, Emerson Collective, Stanford, Perceptive Advisors, Casdin Capital, Marc Benioff, Sands Capital, Breyer Capital, Tailwinds (American-Korean) etc.
Its Scientific Advisory Board includes Jim Allison (Nobel Laureate, Immuno Oncology), Bob Langer (MIT, co-founder Moderna), Phil Greenberg (Hutch, co-founder Juno), Pam Sharma (MD Anderson), Charlie Rudin (Sloan Kettering), Alan Ashworth (UCSF Cancer Center).
Who You Are
- You share our same sense of dedication, scientific passion and entrepreneurial spirit
- You work well in a fast-paced and extremely focused startup environment
- You are not only smart, but clever and constantly think outside the box
- You are able to make logical decisions in an instant when there is little time to evaluate
- You are a natural communicator and relationship builder
- You stay calm under high pressure and stress
- You have the ability to multi-task in a serious way, with an extreme attention to detail
- You become a representative of the core DNA of the company through who you are
The Position
Earli is currently seeking a highly motivated and detail-oriented Research Associate to join the Therapeutics team. The successful candidate will play a key role in supporting sample processing and analysis to advance our research projects.
Your Primary Responsibilities
- Extract DNA and RNA from both normal mouse tissues as well as cancer xenografts for the molecular analysis of Earli targets.
- Execute experiments assessing target expression using array of methodologies including but limited to ELISA and RT-qPCR.
- Process normal mouse tissues as well as cancer xenografts into single cell suspension for analysis of the tissue microenvironment by FACS.
- Execute experiments assessing phenotype of normal mouse tissues and cancer xenograft microenvironments using 10+ color FACS panels.
- Using sterile technique, maintain and scale up multiple cell lines for use in functional assays as well as protein production applications.
- Analyze data and maintain accurate records of experimental procedures, data, and results in electronic lab notebooks and databases.
Your Required Experience, Knowledge and Skill
- BS or MS degree in Cell Biology, Molecular Biology, or related sciences field with hands on wet lab experience.
- Experience with basic tissue processing techniques and molecular biology methodologies (ELISA, RT-qPCR, agarose gel electrophoresis) is strongly preferred.
- Experience if mammalian cell culture, cell-based assays (luminescence, fluorescence, etc.), and protein purification is a plus.
- Strong analytical and problem-soling skills with the ability to troubleshoot experimental issues.
- Excellent organizational skills and attention to detail, with the ability to manage multiple tasks simultaneously in a fast-paced environment.
- Effective communication and interpersonal skills, with the ability to work collaboratively in a team setting.
- A 'self-starter' mentality with strong motivation and a keen drive to excel individually and in a team.
- Excellent verbal communication, organization, time management, and interpersonal skills.
- Ability to think independently, multi-task effectively, and fully integrate into a high achieving team environment.
The base salary for this role is $60k-$95k per year.
If interested in applying, please attach a CV or have a well-developed LinkedIn profile for us to be able to assess your background.
We look forward to hearing from you
-
Foster City, California, United States Gilead Sciences, Inc. Full timeSenior Research Associate II- Protein TherapeuticsUnited States - California - Foster CityGilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients...
-
Senior Research Scientist
2 days ago
Redwood City, California, United States Valid8 Financial, Inc. Full timeAbout the RoleWe are seeking a highly skilled Senior Research Scientist to join our team at Valid8 Financial, Inc. as a Lead Scientist, Translational Research. This is a unique opportunity to contribute to the development of novel nanomedicines and HD therapeutics for the treatment of unmet medical needs in ophthalmology, neurology, inflammatory diseases,...
-
Senior Research Associate I
1 month ago
Foster City, California, United States Gilead Sciences, Inc. Full timeSenior Research Associate I - Protein TherapeuticsUnited States - California - Foster CityGilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients...
-
Senior Research Associate II
2 days ago
Foster City, California, United States ATR International Full timeJob Description:We are seeking a highly skilled Senior Research Associate II to provide bioanalytical support to our biologics discovery project teams at ATR International. The successful candidate will work closely with cross-functional teams to optimize leads and select candidates for clinical evaluation.The primary responsibility of this Biologics...
-
Senior Research Associate I Antibody Discovery
4 weeks ago
Foster City, California, United States Gilead Sciences, Inc. Full timeSenior Research Associate I Antibody DiscoveryUnited States - California - Foster CityGilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living...
-
Senior Research Associate, Gene Regulation
2 months ago
Redwood City, California, United States Earli Inc. Full timeAbout Earli Earli exists to make cancer a benign experience. Earli does that by turning cancers against themselves: genetically forcing them to reveal themselves early, and then kill themselves – precisely and clearly distinguishable from benign lesions at early stages. Based on original technology from Stanford's renowned Gambhir lab, Earli designs...
-
Senior Research Associate II
2 days ago
Foster City, California, United States ATR International Full timeJob SummaryWe are seeking a highly skilled Senior Research Associate II to provide bioanalytical support to our biologics discovery project teams at ATR International. The successful candidate will work closely with cross-functional teams to optimize leads and select candidates for clinical evaluation.Key ResponsibilitiesProvide bioanalytical support to DMPK...
-
Foster City, California, United States Gilead Sciences, Inc. Full timeSenior Research Associate II Biologics Quality Control (Commercial Analytical Operations)United States - California - Foster CityGilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we...
-
Sr. Research Associate II, Protein Therapeutics
2 weeks ago
Foster City, California, United States Gilead Sciences, Inc. Full timeSr. Research Associate II, Protein TherapeuticsUnited States - California - Foster CityGilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living...
-
Principal Research Associate I – Antibody Innovation
14 hours ago
Foster City, California, United States Gilead Sciences Full timeJob Overview At Gilead Sciences, we are dedicated to fostering a healthier future for individuals worldwide. For over 35 years, we have been at the forefront of addressing critical health issues such as HIV, viral hepatitis, COVID-19, and cancer. Our relentless pursuit of innovative therapies aims to enhance lives and ensure their accessibility across...
-
Redwood City, California, United States Bristol-Myers Squibb Full timeSenior Associate Scientist, Immunology and Stromal Biology page is loaded Senior Associate Scientist, Immunology and Stromal Biology Apply locations Redwood City – CA – US Brisbane – CA – US time type Full time posted on Posted 13 Days Ago job requisition id R Working with UsChallenging. Meaningful. Life–changing. Those aren't words that are...
-
Laboratory Research Associate
6 days ago
Foster City, California, United States Infotree Global Solutions Full timeInfotree Global Solutions is seeking a Research Associate with expertise in Histology. This role is essential in providing advanced knowledge in histological techniques, including tissue processing, staining methodologies, and digital pathology, to enhance our pharmaceutical development efforts.Position: Research Associate - Histology SpecialistType: W2...
-
Redwood City, California, United States Corcept Therapeutics Full timeCorcept Therapeutics is at the forefront of innovative research and development focused on cortisol modulators, specialized molecules that influence cortisol activity at the glucocorticoid receptor (GR). With a proven history of over 1,000 proprietary cortisol modulators, we are dedicated to advancing this critical area of medicine.Since receiving FDA...
-
Senior Clinical Research Scientist
6 days ago
Redwood City, California, United States Exact Sciences Full timePosition Overview The Senior Clinical Research Scientist will play a pivotal role in the formulation of clinical evidence strategies, clinical development frameworks, and study methodologies aimed at validating and demonstrating the clinical efficacy of laboratory-developed tests (LDT) and in vitro diagnostic (IVD) products. This role collaborates closely...
-
Foster City, California, United States Gilead Sciences, Inc. Full timeSenior Research Associate II, Purification Process Development - Pre-Pivotal BiologicsUnited States - California - Foster CityGilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek...
-
Foster City, California, United States Gilead Sciences, Inc. Full timeSenior Research Associate I- In Vivo PharmacologyUnited States - California - Foster CityGilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients...
-
Senior Clinical Research Manager
6 days ago
Redwood City, California, United States Katalyst Healthcares & Life Sciences Full timePosition Summary:As a Senior Clinical Research Manager, you will be at the forefront of our clinical operations, guiding cross-disciplinary teams to adhere to international operational standards and protocols.Key Responsibilities:Oversee the selection, onboarding, and management of external vendors.Collaborate on critical study parameters and proactively...
-
Lead Clinical Research Specialist
13 hours ago
Redwood City, California, United States Rezolute, Inc. Full timePosition OverviewThe Senior Clinical Research Associate will collaborate closely with the Clinical Operations team to facilitate comprehensive study activities, encompassing site initiation, patient engagement, study oversight, and management of sites and vendors. This role requires cross-functional collaboration within the Rezolute, Inc. team as well as...
-
Senior Clinical Research Scientist
6 days ago
Redwood City, California, United States Exact Sciences Full timePosition Overview The Senior Clinical Research Scientist will play a pivotal role in the formulation of clinical evidence strategies, clinical development frameworks, and study architectures aimed at validating and demonstrating the clinical utility of laboratory-developed tests (LDT) and in vitro diagnostic (IVD) products. This role collaborates closely...
-
Senior Research Scientist I
3 months ago
Foster City, California, United States Gilead Sciences, Inc. Full timeSenior Research Scientist I - Pre-Pivotal Biologics Analytical OperationsUnited States - California - Foster CityGilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve...