Scientist, Antibody Discovery

2 weeks ago


South San Francisco, United States SciPro Full time

Scientist - Antibody Discovery

100% onsite in South San Francisco, CA

6mth contract (with long term contracting opportunity / potential future conversion)


Seeking a Scientist/Sr with background in molecular biology and protein biochemistry to work closely with members of the Antibody Discovery Team to support Large Molecule therapeutic programs.

RESPONSIBILITIES

  • Design strategies and execute antibody discovery campaigns for therapeutic and reagent antibodies using phage display
  • Generate antibody fragment libraries for antibody discovery and engineering, perform HT binding screens (ELISA and multi-plex flow cytometry) and sequence analysis to generate hits
  • Rank-order clones by affinity, in vitro potency, and early developability assessment
  • Execute sequence optimization of lead antibodies to improve developability and binding affinity
  • Design and clone constructs for mAbs, bispecific, and multi-specific antibodies for recombinant antibody production
  • Support NGS-based antibody discovery workflow
  • Present data and updates to management and project teams
  • Follow good documentation practice including maintaining good record keeping in Electronic Notebooks

REQUIRED QUALIFICATIONS AND BACKGROUND

  • PhD in Biochemistry, Biomedical/Chemical Engineering, Immunology, or related field with minimum of 2 years of post-graduate experience (preferably in industry), MS with 8+ years of research experience, BS with 10+ years of research experience in antibody or protein engineering
  • Significant experience in antibody discovery and protein engineering by using single B cell cloning, hybridoma, or phage/yeast display techniques
  • Strong background in molecular biology, antibody and protein expression, and biophysical characterization of recombinant antibodies and proteins

ADDITIONAL PREFERENCES

  • Experience in single domain antibodies, multi-specific antibody engineering, Fc engineering, antibody drug conjugates, naïve phage or yeast display library design
  • Experience in NGS analysis for antibody discovery and engineering
  • Significant contributions to successful biologics drug discovery programs in industry


  • South San Francisco, California, United States Global Channel Management, Inc Full time

    Job SummaryGlobal Channel Management, Inc is seeking a highly skilled Antibody Discovery Scientist to join our team. As a key member of our biologics discovery team, you will be responsible for designing and executing antibody discovery campaigns for therapeutic and reagent antibodies using phage display.Key ResponsibilitiesDesign and execute antibody...


  • san francisco, United States SciPro Full time

    Scientist - Antibody Discovery100% onsite in South San Francisco, CA6-12mth contract (with long term contracting opportunity / potential future conversion)Seeking a Scientist/Sr with background in molecular biology and protein biochemistry to work closely with members of the Antibody Discovery Team to support Large Molecule therapeutic...


  • san francisco, United States SciPro Full time

    Scientist - Antibody Discovery100% onsite in South San Francisco, CA6-12mth contract (with long term contracting opportunity / potential future conversion)Seeking a Scientist/Sr with background in molecular biology and protein biochemistry to work closely with members of the Antibody Discovery Team to support Large Molecule therapeutic...


  • South San Francisco, United States Net2Source Inc. Full time

    Job Description:Job Description: Scientist Consultant, Antibody DiscoveryLocation: South San Francisco, CA 94080Duration: 12+ Months (Extendable)Pay Rate: $87.00/hr on W2Qualifications:PhD in Biochemistry, Biomedical/Chemical Engineering, Immunology, or related field with minimum of 2 years of post-graduate experience (preferably in industry), MS with 8+...


  • South San Francisco, United States System One Full time

    Job Title: Scientist Consultant, Antibody Discovery (PhD) Location: San Francisco, CA Shift: M-F 8-5 Type: Contract, 1 year Pay : Up to $84.75/hour depending upon experience Qualifications: PhD in Biochemistry, Biomedical/Chemical Engineering, Immunology, or related field with minimum of 2 years of post-graduate experience...


  • South San Francisco, United States Integrated Resources, Inc ( IRI ) Full time

    Job Description: • Design strategies and execute antibody discovery campaigns for therapeutic and reagent antibodies using phage display• Generate antibody fragment libraries for antibody discovery and engineering, perform HT binding screens (ELISA and multi-plex flow cytometry) and sequence analysis to generate hits• Rank-order clones by affinity, in...


  • South San Francisco, United States eTeam Full time

    Title: Bio-conjugation ScientistLocation: South San Francisco, CA 94080Duration: 12 months’Pay rate: $66/hrThis is a Bio-conjugation Scientist role. • Minimum 8 years of relevant industry experience is needed with BS/MS and 5 years with PHD.Required:• Hands on experience with conjugation, purification and characterization of antibody drug conjugates,...


  • South San Francisco, United States eTeam Full time

    Title:: Bio-conjugation ScientistLocation: South San Francisco, CA 94080Duration: 12 MonthsPay Rate: $66/hrResponsibilities:This is a Bio-conjugation Scientist role with MRL SSF Discovery Chemistry group.Client is currently seeking highly motivated and exceptional a Bio-conjugation Scientist for positions within the Discovery Chemistry Department located at...


  • san francisco, United States eTeam Full time

    Title:: Bio-conjugation ScientistLocation: South San Francisco, CA 94080Duration: 12 MonthsPay Rate: $66/hrResponsibilities:This is a Bio-conjugation Scientist role with MRL SSF Discovery Chemistry group.Client is currently seeking highly motivated and exceptional a Bio-conjugation Scientist for positions within the Discovery Chemistry Department located at...

  • Scientist

    19 minutes ago


    South San Francisco, United States Integrated Resources, Inc ( IRI ) Full time

    Title: Scientist Consultant, Antibody DiscoveryLocation: South San Francisco, CADuration: 12 monthsJob Description:Design strategies and execute antibody discovery campaigns for therapeutic and reagent antibodies using phage display.Generate antibody fragment libraries for antibody discovery and engineering, perform HT binding screens (ELISA and multi-plex...


  • South San Francisco, United States BEPC Inc. - Business Excellence Professional Consulting Full time

    BEPC is actively looking for a Research Associate in the South San Francisco, CA area!Benefits include medical, dental, vision, and life insurancePay Rate: $44.60-$48.60/hourNO C2C CandidatesThe Antibody Engineering Department works to shape the future of medicine by discovering life-changing antibody therapies through pioneering science.We are seeking a...


  • South San Francisco, California, United States Amgen Full time

    HOW MIGHT YOU DEFY IMAGINATION?Youve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology...

  • Research Scientist

    2 weeks ago


    South San Francisco, United States Net2Source Inc. Full time

    Title: Translational Research Scientist - I (Assistant) Location: South San Francisco, CA 94080 (Onsite) Duration: 12+ months of Contract (Possibility of extension)Payrate:$66/hr on W2 without benefitsJob ID - 36218Must haves:Antibody drug conjugation experience hydrophobic interaction chromatography or ion exchange chromatography or LC/MS.100% onsite Lab...

  • Senior Scientist

    3 weeks ago


    South San Francisco, United States Net2Source Inc. Full time

    Title: Translational Research Scientist - I (Assistant) Location: South San Francisco, CA 94080 (Onsite) Duration: 12+ months of Contract (Possibility of extension)Must haves:Antibody drug conjugation experiencehydrophobic interaction chromatography or ion exchange chromatography or LC/MS.100% onsite Lab based roleJob Description:This is a Bio-conjugation...


  • South San Francisco, United States Net2Source Inc. Full time

    Job Description: Bioconjugation, Large Molecule DiscoveryLocation: South San Francisco, CA 94080Duration: 12+ Months (Extendable)Pay Rate: $87.00/hr on W2Qualifications:A BS or MS with 1-3+ years relevant work experience. Level commensurate with education and experience.Level commensurate with education and experience• Excellent interpersonal skills with...


  • South San Francisco, United States Net2Source Inc. Full time

    Job Description: Bioconjugation, Large Molecule DiscoveryLocation: South San Francisco, CA 94080Duration: 12+ Months (Extendable)Pay Rate: $87.00/hr on W2Qualifications:A BS or MS with 1-3+ years relevant work experience. Level commensurate with education and experience.Level commensurate with education and experience• Excellent interpersonal skills with...

  • Sr. Advisor

    4 weeks ago


    San Diego, United States Eli Lilly and Company Full time

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...

  • Sr. Advisor

    1 month ago


    San Diego, United States Eli Lilly and Company Full time

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...


  • San Francisco, California, United States Dreamforce Services Inc. Full time

    Job Description**Job Summary:**We are seeking a highly motivated and exceptional Bioconjugation Scientist to join our Discovery Chemistry Department at Dreamforce Services Inc. in South San Francisco, CA.Key Responsibilities:Conjugation Expertise: Perform bioconjugations of linker-payload combinations to antibodies using in-house established...


  • South San Francisco, California, United States Roche and Genentech Full time

    Job OverviewPosition Summary:We are in search of a dedicated professional to contribute to the Department of Antibody Engineering at Roche and Genentech as a Laboratory Research Scientist. This position entails the design and execution of hands-on laboratory experiments alongside data analysis and interpretation.A key focus will be on the experimental...