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Computational Biologist 1

3 months ago


Portland, Oregon, United States Oregon Health & Science University Full time

Overview

The OHSU Knight Cancer Institute is a world leader in treating leukemia. Our CEO and former director, Dr. Brian Druker, is an internationally recognized pioneer in precision cancer medicine. Dr. Druker played a central role in developing Gleevec, a daily pill for chronic myelogenous leukemia (CML) that has saved tens of thousands of lives. Now, he is helping lead Beat AML, a major effort to find better treatments for acute myeloid leukemia.

Every Knight Cancer employee is expected to embody our guiding principles:

We act BOLDLY—Breakthroughs require pushing the boundaries of science, exploring new frontiers, and thinking differently We SUPPORT each other—Respect leads to trust, which leads to excellence We work as a CONNECTED team—We must leverage our collective brain power to conquer cancer because no one individual can do it alone

Function/Duties of Position

An exciting opportunity has been created for an experienced researcher to join Dr. Olga Nikolova's group as a Computational Biologist I at Oregon Health & Science University in Portland, OR. Dr. Nikolova's research program is focused on predictive models for cancer biology, with a special interest in leukemia.

Duties will include computational analysis of genomic bulk and single-cell data in both single modalities and multi-omes, including RNAseq, ATACseq, CITE-seq, CyTOF, and custom assays developed in-house. Applicant will establish and maintain pipelines and participate in data analysis and visualization. The applicant will develop new tools and methods for analyzing emerging data types and adapt statistical methods to assess the robustness of new tools. The applicant will be able to independently interact with wet-lab biologists to analyze data and guide the analysis strategy. Will be responsible for the deposition of sequencing data and published algorithms. Will work with other investigators to enable their use of algorithms developed by the team. Will participate in the writing of grants and manuscripts. Applicants will need to possess strong organizational and communication skills and the ability to work collaboratively.

Experience with R, Python, and Bash/Unix is required. Salary will be commensurate with experience. We are looking for an enthusiastic individual who is capable and willing to make maximum use of excellent facilities and a productive environment.

Required Qualifications

Education & experience:

Master's Degree in Computational Biology or related field OR Bachelor's Degree in Computational Biology or related field AND 3 years of relevant experience

Knowledge, skills, and abilities:

Proficient with computers, relevant programming languages, and environments, methods, and tools Technical proficiency, scientific creativity, collaborative ability, and independent thinker Proven ability to work collaboratively with a high-performing work group Must have excellent communication, analytical, and organizational skills: both written and verbal Ability to work independently and as part of a team while being collaborative in resolving problems Demonstrated ability to learn new and innovative processes quickly Must possess energy and drive to coordinate multiple projects simultaneously Ability to use tact and diplomacy to maintain effective working relationships

Preferred Qualifications

4 years of experience with computational analysis of genomic data Experience with analysis of single-cell data, such as scRNA-seq, CITE-seq, scATAC-seq

Additional Details

Apply online. Please be sure to upload a Cover Letter and Resume/CV.

We offer a variety of benefits on top of joining a thriving organization:

Medical, dental and vision coverage at no or low cost to employeesCovered 100% for full-time employees and 88% for dependents Several retirement plans to choose from with contributions from OHSU 25 days a year of paid time off 8 days of sick time off Commuter subsidies Tuition reimbursement Access to group life insurance, disability insurance and other supplemental benefits Annual Merit Increase Growth/Development Opportunities Employee discounts to local and major businesses

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All are welcome

Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at or