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Research Assistant I

3 months ago

Horsham, Pennsylvania, United States Charles River Laboratories Full time
Research Assistant I - Molecular Biology

Req ID #: 222777

Location:
Horsham, PA, US, 19044


For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies.

When you join our family, you will have a significant impact on the health and well-being of people across the globe.

Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform.

In return, we'll help you build a career that you can feel passionate about.

Job Summary


Serve as research technician for conducting basic to moderately complex molecular biology assays to support pre-clinical safety and toxicity studies.

Perform DNA/RNA purification and quantitation, qPCR. qRT-PCR etc.) in compliance with SOPs and GLP regulations. Work with scientific staff to develop new methods and conduct assay validation.

ESSENTIAL DUTIES AND RESPONSIBILITIES:

  • Perform routine molecular biology techniques such as DNA/RNA purification from cells, tissues and biofluids, quantitate DNA/RNA and set up qPCR/qRT-PCR/dd-RT-PCR reactions with supervision.
  • Perform routine sample analysis and assist in preparation of summary study data tables.
  • Work with scientific staff to develop new methods and conduct validation experiments.
  • Prepare and maintain study notebooks and submit timely for audit
  • Review documentation of functions performed by peers as part of quality control requirements.
  • Prepare responses to internal Quality Assurance audits with supervision
  • Perform laboratory procedures and collect and record/document research data in compliance with Good Laboratory Practices (GLPs), Standard Operating Procedures (SOPs) study protocols, study and laboratory-specific methods or procedures, and company policies/practices.
  • Calibrate and maintain laboratory equipment and instrumentation.
  • Maintain clean work areas
  • Perform all other related duties as assigned.
The pay range for this position is between $25.00 and $26.00 an hour .

Please note that salaries vary within the range based on factors including, but not limited to, experience, skills, education, certifications, and location.

Job Qualifications

QUALIFICATIONS:

  • Education: Bachelor's degree (B.A./B.S.) or equivalent in a life sciences or related discipline required.
  • Experience: Zero to two years related experience in biology, chemistry/pharmacy in a contract lab or similar lab environment.
  • An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
  • Certification/Licensure: None.
  • Other: Ability to carry out standard laboratory calculations. Knowledge of GLPs and other federal regulations and guidelines desired. Must be able to perform effectively as a team member, accurately record data, follow verbal and written instructions, communicate effectively, and interact in a professional manner with management, coworkers, and sponsors.

PHYSICAL DEMANDS:

  • Employees must be able to lift, move, manipulate, and/or hold heavy objects up to and including 50 pounds; this includes work materials, equipment, and/or supplies.
  • Must be able to perform procedures, which require, talking, hearing, standing or sitting for long periods of the workday, entering data into a computer, using appropriate instruments, reaching with hands and arms, working in narrow spaces, and wearing safety equipment (PPE) according to OSHA regulations and company standards.
  • Must be able to frequently firmly hold and manipulate work materials while utilizing fine motor skills.
  • Specific vision abilities required by this job include close vision, color vision, depth perception, and the ability to adjust focus.

WORK ENVIRONMENT:

  • Works in a research environment, which requires use of sharp objects, working around mechanical parts, working with or near known or unknown toxic or caustic chemicals and/or biological hazards, exposure to fumes and airborne particles, working at noise levels ranging from moderate to loud.
  • While performing the duties of this job the employee is regularly required to wear protective clothing (i.e., goggles, face shield, cap, gloves, scrubs, shoe covers), work near toxic or caustic chemicals, work with biohazards.
  • May occasionally be exposed to fumes or airborne particles, unpleasant odors and extreme temperature conditions.
  • The employee may be occasionally exposed to live animals with risk of exposure to allergens, zoonotic disease, and biohazards.
  • The noise level in the work environment ranges from low to moderate depending upon the task being performed.

COMMENTS:

  • This position requires overtime, weekend, holiday, and/or after hours shift coverage, as needed.
About Safety Assessment


Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance.

From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market.

Each year approximately 300 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.

About Charles River

Charles River is an early-stage contract research organization (CRO).

We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development.

Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities.

Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.


With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges.

Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.

At Charles River, we are passionate about our role in improving the quality of people's lives.

Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe.

We have proudly supported the development of 86% of the drugs approved by the FDA in 2021.

Equal Employment Opportunity


Charles River Laboratories is an Equal Opportunity Employer - all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.


If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.

For more information, please visit

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