Current jobs related to Associate Director, Clinical Pharmacology and DMPK - South San Francisco, California - Alumis Inc.
-
Vice President of Clinical Pharmacology
4 weeks ago
South San Francisco, California, United States Recruits Lab (We're hiring) Full timeAre you prepared to lead transformative precision medicine initiatives in oncology? Recruits Lab (We're hiring) is in search of an exceptional Vice President of Clinical Pharmacology to become a key member of our innovative team.About Us: We are at the forefront of precision medicine in oncology, dedicated to the discovery and advancement of targeted...
-
Clinical Pharmacology Director
2 days ago
San Francisco, California, United States Daiichi Sankyo, Inc. Full timeAssociate Director, Clinical PharmacologyAbout the RoleWe are seeking an experienced Associate Director to lead our Clinical Pharmacology team. As a key member of our development team, you will be responsible for developing and implementing Clinical Pharmacology and Modeling & Simulation plans from First-in-Human to post-registration.Key...
-
Associate Director Clinical Pharmacology
2 weeks ago
San Francisco, California, United States TANNER & ASSOC INC Full timeAssociate Director Clinical Pharmacology - San Francisco BiotechNew Position: Associate Director Clinical Pharmacology - San Francisco Biotech**Job Summary:**The Associate Director Clinical Pharmacology role at Tanner & Assoc Inc. is a strategic position requiring a strong background in clinical pharmacology and leadership skills. The ideal candidate will...
-
Clinical Pharmacology Director
2 weeks ago
San Francisco, California, United States Pliantrx Full timeAbout the RolePliant Therapeutics is seeking a highly skilled and experienced Clinical Pharmacology Director to join our team in South San Francisco. As a key member of our Clinical Pharmacology department, you will be responsible for leading the development of clinical pharmacology strategies and plans across multiple indications.Key ResponsibilitiesStudy...
-
DMPK Principal Scientist or Associate Director
3 weeks ago
San Diego, California, United States Genesis Therapeutics Full timeSenior DMPK Expert Opportunity at Genesis TherapeuticsWe are seeking a highly motivated and versatile Senior DMPK Expert to join our team in San Diego.About the RoleRepresent DMPK as the technical expert on project teams, providing scientific and strategic leadership for all stages of discovery and early development.Design, develop, execute (or manage...
-
Clinical Pharmacology Director
2 days ago
San Francisco, California, United States Daiichi Sankyo, Inc. Full timeJob Summary:The Clinical Pharmacology Director will be responsible for creating model-based drug development plans, designing, conducting, and interpreting Phase 1 studies, supporting Phase 2/3 studies, and representing the function on study and project teams. This position requires a strong understanding of PK-PD and Pop PK-PD concepts and analysis, phase...
-
Head of Clinical Pharmacology
4 weeks ago
San Diego, California, United States AnaptysBio Inc Full timeAnaptysBio Inc is committed to providing equal employment opportunities to all qualified candidates without discrimination based on race, color, sex, sexual orientation, gender identity, religion, national origin, disability, veteran status, age, marital status, pregnancy, genetic information, or any other legally protected status. Position OverviewThis role...
-
DMPK Principal Scientist
5 days ago
San Diego, California, United States Genesis Therapeutics Full timeAbout the RoleWe are seeking a highly skilled DMPK Principal Scientist to join our team at Genesis Therapeutics. As a key member of our drug discovery and development team, you will be responsible for driving the overall PKPD modeling and simulation effort to support projects from early research through early clinical development.Key...
-
Senior Research Scientist, DMPK
2 weeks ago
San Diego, California, United States Neurocrine Biosciences Full timeAbout the RoleWe are seeking a highly skilled Senior Research Scientist, DMPK to join our multidisciplinary discovery and development team at Neurocrine Biosciences. As a key member of our team, you will play a critical role in advancing our medicines, including small molecules, biologics, peptides, and gene therapies.Key ResponsibilitiesParticipate in all...
-
Senior Clinical Pharmacology Director
2 weeks ago
San Francisco, California, United States Allergan Full timeJob SummaryWe are seeking a highly experienced and skilled Senior Clinical Pharmacology Director to join our team at Allergan. As a key member of our Clinical Pharmacology department, you will be responsible for leading strategic planning for drug development activities and projects to achieve departmental strategies, goals, and objectives.Key...
-
Clinical Pharmacology Director
2 weeks ago
San Diego, California, United States Longboard Pharmaceuticals, Inc. Full timeAbout the RoleWe are seeking a highly skilled Clinical Pharmacology Director to join our team at Longboard Pharmaceuticals, Inc. As a key member of our Clinical Pharmacology group, you will play a critical role in driving the development of our pharmaceutical products.Key ResponsibilitiesLead Clinical Pharmacology Strategy: Develop and execute clinical...
-
San Francisco, California, United States Eli Lilly and Company Full timeAbout the RoleWe are seeking a highly skilled and experienced Director, Drug Metabolism and Pharmacokinetics to join our team at Eli Lilly and Company. As a key member of our research organization, you will be responsible for providing scientific leadership and strategic direction to research project teams, ensuring the successful advancement of research...
-
DMPK Principal Scientist
2 weeks ago
San Diego, California, United States Genesis Therapeutics Full timeAbout the RoleWe are seeking a highly skilled and experienced DMPK Principal Scientist to join our team at Genesis Therapeutics. As a key member of our research team, you will be responsible for driving the overall PKPD modeling and simulation effort to support projects from early research through early clinical development.Key ResponsibilitiesRepresent DMPK...
-
Senior Director of In Vivo Pharmacology
2 weeks ago
San Francisco, California, United States Parvus Therapeutics, Inc. Full timeAbout the RoleWe are seeking a highly experienced Associate Director to lead our In Vivo Pharmacology Team and manage projects enabling the development of Navacims towards clinical evaluation. This role will also establish research and discovery efforts to foster our Parvus product pipeline growth.Key ResponsibilitiesDevelop and Conduct Immunological Models:...
-
Senior Director, In Vivo Pharmacology
2 weeks ago
San Francisco, California, United States Tbwa ChiatDay Inc Full timeJob SummaryWe are seeking a highly experienced and skilled Senior Director, In Vivo Pharmacology to join our Research team at SonoThera. As a key member of our team, you will be responsible for leading the design, implementation, and oversight of in vivo pharmacology studies to support our gene therapy programs.Key ResponsibilitiesProvide strategic...
-
DMPK Project Lead
4 hours ago
San Diego, California, United States BioPhase Solutions Full timeJob Title: DMPK Project RepresentativeAt BioPhase Solutions, we are seeking a highly skilled DMPK Project Representative to join our team. As a key member of our drug development team, you will be responsible for leading efforts within the drug metabolism and pharmacokinetics (DMPK) area, working closely with multidisciplinary project teams to provide...
-
Senior Director of In Vivo Pharmacology
2 weeks ago
San Francisco, California, United States Meet Full timeAbout MeetMeet is a venture-backed, early-stage biopharmaceutical company that has developed a novel ultrasound-guided, non-viral gene therapy platform to provide patients with the next generation of genetic medicines.Our MissionWe are driven by a collaborative, interdisciplinary, and forward-thinking approach to solving the current challenges facing genetic...
-
Quantitative Clinical Pharmacology Manager
23 hours ago
San Francisco, California, United States Daiichi Sankyo, Inc. Full timeUnlock Your Potential in Clinical PharmacologyDaiichi Sankyo, Inc. is a global pharmaceutical innovator dedicated to creating and supplying innovative therapies to improve healthcare standards worldwide. With a rich legacy of innovation and a robust pipeline of promising new medicines, we are committed to addressing diversified, unmet medical needs of people...
-
South San Francisco, California, United States Lycia Therapeutics Full timeCompany Overview:Lycia Therapeutics, Inc. is a pioneering biotechnology firm that utilizes its innovative lysosomal targeting chimera (LYTAC) platform, developed by Chemistry Nobel Laureate Carolyn Bertozzi, to discover and create groundbreaking therapeutics aimed at degrading extracellular and membrane-bound proteins.Our next-generation degraders exploit...
-
Senior Scientist
4 weeks ago
San Diego, California, United States Clinical Dynamix Full timeSenior Scientist - Quantitative PharmacologyWe are pleased to present an exciting opportunity for a skilled Senior Scientist to become part of a leading BioPharmaceutical organization. In this position, you will be an integral member of the Quantitative Pharmacology team, utilizing model-informed drug development methodologies to facilitate the advancement...
Associate Director, Clinical Pharmacology and DMPK
3 months ago
Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer – our goal is to fundamentally change the outcomes for these patients.
This position is a key member of the development team, executing clinical drug development activities by evaluating the clinical pharmacology of antibody therapeutics in an excellent organization that focuses primarily, but not exclusively, on immune-inflammatory diseases. This position reports to the head of clinical pharmacology and DMPK and liaises with clinical development, clinical operations, non-clinical pharmacology and toxicology, and drug discovery to execute activities for advancing the development pipeline.
Essential Functions
Contribute clinical pharmacology sections of clinical study protocols and reports and regulatory documents including Investigator Brochures, and NDA/IB/IMPDs
Conduct hands-on non-clinical and clinical data analysis, including non-compartmental, PK/PD and modeling analyses where applicable
Oversees the development and validation of quantitative in vivo assays to enable PK/PD characterization of therapeutic antibodies
Work with nonclinical Pharmacology and Toxicology to design, analyze and interpret PK./PD relationship and toxicokinetic data
Collaborate with the clinical operations, clinical development, biostatistics/data sciences, and cross-functional project teams
Work closely with bioanalysis CROs to ensure that all studies are performed in high quality and timely manner to meet program milestones and goals
Work with Clinical Operations to ensure clinical PK/PD/Biomarker samples are well managed
Review clinical study protocols to ensure PK, PD and Biomarker sampling time points are consistent with study design
Manage CRO activities and ensure Good Laboratory Practice (GLP) and Good Clinical Practice (GCP) compliance
Identify, scope out and select new clinical pharmacology/bioanalysis vendors as needed
Work with internal legal and finance to execute service contracts with CRO labs
Possesses excellent communication skills to work efficiently with all stakeholders
Qualifications Requirments
PhD, PharmD or equivalent in Pharmacokinetics, Pharmacology, Bioanalytical or related field with at least 5+ years of experience in Clinical Pharmacology, DMPK or related disciplines required.
Knowledge and Competencies:
Knowledge of pharmacokinetics and pharmacodynamics (PK/PD) and DMPK principles
Familiarity with regulatory guidelines such as ICH, GLP and GCPs
Working knowledge of clinical pharmacology related software tools such as WinNonlin, NONMEM, SympCyp and/or R
Knowledge of small molecule bioanalytical assays used to support PK studies
Experience and knowledge in translational methodologies to advance molecules from preclinical to first-in-human studies
Knowledge of quantitative pharmacology, modeling and simulation or advanced data analysis
Excellent team skills and proven ability to work within multi-disciplinary teams to influence the overall direction of projects
Strong ability to prioritize daily work based on changing business requirements
Excellent ability to multi-task in a high-energy, dynamic environment
Self-motivated, independent, and results-oriented
Ability to work productively in a matrix environment, as a team contributor taking ownership of multiple projects
Physical Demands
The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
While performing the duties of this job, the employee is regularly required to sit and talk or hear. The employee frequently is required to use hands to finger, handle, or feel. The employee is occasionally required to stand, walk, and reach with hands and arms. The employee must occasionally lift and/or move up to 10 pounds. Specific vision abilities required by this job include close vision and ability to adjust focus in order to read.
Work Environment
The work environment characteristics are representative of those an employee encounters while performing the essential functions of this job, typically in an open office environment. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
The noise level in the work environment is usually moderate.
May be required to travel by plane or car
This position requires working with biological and/or chemical hazards
Alumis Values
Elevate
Challenge
Nurture
This position is located in South San Francisco, CA. At this time we are not considering remote applicants.
The salary range for this position is $198,000 USD to $215,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company's compensation practices.
Alumis Inc. is an equal opportunity employer.