Program Director, RNA Therapeutics

3 weeks ago


Boston, United States Ginkgo Bioworks, Inc Full time
  • The successful applicant will have a deep technical background in RNA biology and understands how to deploy various toolkits including cell engineering, genetics and functional genomics, NGS, and high-throughput screening approaches to design better RNA sequences that support long-term or tissue-specific translation.
  • Expertise is required with how RNA secondary structure and topology affects both its generation ( in vitro or in vivo ) and its function.
  • Knowledge of in vitro transcription methods for generating RNAs and familiarity with RNassociated immunogenicity is important.
  • Please note: this role could be based in either our Seaport or Cambridge locations, but requires some flexibility to occasionally be present at the other location.
  • PhD or equivalent experience in molecular biology, bioengineering, synthetic biology, or related field
  • Direct experience and technical leadership in projects investigating RNA sequence-structure-function relationships in the context of translation, stability, catalysis, interference, or any other RNA process.
  • Strong molecular biology expertise, with significant experience in mammalian cell culture and familiarity with next-generation sequencing technologies
  • Direct experience and technical leadership in generating and screening large libraries of RNA elements to elucidate sequence-structure-function relationships between those elements and RNA processes (ie catalysis, translation, stability, interference, etc)


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