Program Director, RNA Therapeutics
3 weeks ago
- The successful applicant will have a deep technical background in RNA biology and understands how to deploy various toolkits including cell engineering, genetics and functional genomics, NGS, and high-throughput screening approaches to design better RNA sequences that support long-term or tissue-specific translation.
- Expertise is required with how RNA secondary structure and topology affects both its generation ( in vitro or in vivo ) and its function.
- Knowledge of in vitro transcription methods for generating RNAs and familiarity with RNassociated immunogenicity is important.
- Please note: this role could be based in either our Seaport or Cambridge locations, but requires some flexibility to occasionally be present at the other location.
- PhD or equivalent experience in molecular biology, bioengineering, synthetic biology, or related field
- Direct experience and technical leadership in projects investigating RNA sequence-structure-function relationships in the context of translation, stability, catalysis, interference, or any other RNA process.
- Strong molecular biology expertise, with significant experience in mammalian cell culture and familiarity with next-generation sequencing technologies
- Direct experience and technical leadership in generating and screening large libraries of RNA elements to elucidate sequence-structure-function relationships between those elements and RNA processes (ie catalysis, translation, stability, interference, etc)
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Scientist - RNA Therapeutic Discovery
4 days ago
Boston, United States ascidian therapeutics Full timeAbout us: Ascidian is redefining the treatment of disease by rewriting RNA. Ascidian Therapeutics was founded to rewrite RNA by editing and replacing human exons. We were inspired by ocean creatures, called Ascidians, who are primordial ancestors of vertebrates. To grow from larvae to adults, ascidians re-engineer their transcriptome through RNA editing...
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SCIENTIST - RNA THERAPEUTIC DISCOVERY
5 days ago
Boston, MA 02298, USA, United States ascidian therapeutics Full timeAbout us:Ascidian is redefining the treatment of disease by rewriting RNA.Ascidian Therapeutics was founded to rewrite RNA by editing and replacing human exons. We were inspired by ocean creatures, called Ascidians, who are primordial ancestors of vertebrates. To grow from larvae to adults, ascidians re-engineer their transcriptome through RNA editing via...
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Boston, United States ascidian therapeutics Full timeAbout us: Ascidian is redefining the treatment of disease by rewriting RNA. Ascidian Therapeutics was founded to rewrite RNA by editing and replacing human exons. We were inspired by ocean creatures, called Ascidians, who are primordial ancestors of vertebrates. To grow from larvae to adults, ascidians re-engineer their transcriptome through RNA editing...
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Program Director, RNA Therapeutics
3 weeks ago
Boston, Massachusetts, United States Ginkgo Bioworks, Inc Full timeThe successful applicant will have a deep technical background in RNA biology and understands how to deploy various toolkits including cell engineering, genetics and functional genomics, NGS, and high-throughput screening approaches to design better RNA sequences that support long-term or tissue-specific translation.Expertise is required with how RNA...
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Boston, MA, United States Amplitude Therapeutics Full timeCompany summary: Amplitude Therapeutics is a seed-staged biotechnology company focusing on developing the next generation of RNAs to fully unlock the therapeutic potential of RNA biology. We are founded by leaders in the RNA and non-viral therapy fields and backed by premier Biotech VCs. Position summary: We are seeking a Senior / Principal Research...
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Boston, Massachusetts, United States Scorpion Therapeutics Full timeScorpion is a pioneering clinical-stage oncology company redefining the frontier of precision medicine to deliver optimized and transformational therapies for larger populations of patients with cancer. Scorpion has built a proprietary and fully integrated platform of the most advanced technologies across cancer biology, medicinal chemistry, and data...
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Head of Data Science
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Boston, United States Ascidian Therapeutics Full timeAbout us: Ascidian is redefining the treatment of disease by rewriting RNA. Ascidian Therapeutics was founded to rewrite RNA by editing and replacing human exons. We were inspired by ocean creatures, called Ascidians, who are primordial ancestors of vertebrates. To grow from larvae to adults, ascidians re-engineer their transcriptome through RNA editing via...
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Clinical Trial Manager
2 weeks ago
Boston, United States Ascidian Therapeutics Full timeAbout us:Ascidian is redefining the treatment of disease by rewriting RNA.Ascidian Therapeutics was founded to rewrite RNA by editing and replacing human exons. We were inspired by ocean creatures, called Ascidians, who are primordial ancestors of vertebrates. To grow from larvae to adults, ascidians re-engineer their transcriptome through RNA editing via...
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Clinical Trial Manager
5 days ago
Boston, United States Ascidian Therapeutics Full timeAbout us: Ascidian is redefining the treatment of disease by rewriting RNA. Ascidian Therapeutics was founded to rewrite RNA by editing and replacing human exons. We were inspired by ocean creatures, called Ascidians, who are primordial ancestors of vertebrates. To grow from larvae to adults, ascidians re-engineer their transcriptome through RNA editing via...
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Clinical Trial Manager
4 days ago
Boston, United States Ascidian Therapeutics Full timeAbout us: Ascidian is redefining the treatment of disease by rewriting RNA. Ascidian Therapeutics was founded to rewrite RNA by editing and replacing human exons. We were inspired by ocean creatures, called Ascidians, who are primordial ancestors of vertebrates. To grow from larvae to adults, ascidians re-engineer their transcriptome through RNA editing via...
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Director/Sr. Director
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Boston, United States Tango Therapeutics Full timeCompany Overview Tango Therapeutics is a biotechnology company dedicated to discovering novel drug targets and delivering the next generation of precision medicine for the treatment of cancer. Using an approach that starts and ends with patients, Tango leverages the genetic principle of synthetic lethality to discover and develop therapies that take aim at...
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Director, Applications Development Management
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Director/Sr. Director, Clinical Science
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Molecular Pharmacologist
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Molecular Pharmacologist
2 weeks ago
Boston, United States Kojin Therapeutics Full timeWe are seeking an initiative-taking, creative, and curious scientist to join our growing preclinical pharmacology team. The ideal candidate will have solid molecular pharmacology background related to cancer or other diseases, demonstrated experience in studying mechanisms involved in pathologies, drug mechanism of action, proficient in laboratory skills...
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Molecular Pharmacologist
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Boston, United States Kojin Therapeutics Full timeWe are seeking an initiative-taking, creative, and curious scientist to join our growing preclinical pharmacology team. The ideal candidate will have solid molecular pharmacology background related to cancer or other diseases, demonstrated experience in studying mechanisms involved in pathologies, drug mechanism of action, proficient in laboratory skills...
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Director/Senior Director, Clinical Pharmacology
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Director, Drug Substance Manufacturing
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Director/Sr. Director, Medicinal Chemistry
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