Senior / Principal Research Associate: Infectious Disease Vaccines

3 weeks ago


Boston MA, United States Amplitude Therapeutics Full time

Company summary:

Amplitude Therapeutics is a seed-staged biotechnology company focusing on developing the next generation of RNAs to fully unlock the therapeutic potential of RNA biology. We are founded by leaders in the RNA and non-viral therapy fields and backed by premier Biotech VCs.

Position summary:

We are seeking a Senior / Principal Research Associate to join our growing therapeutics team. The key functions for this lab-based role is to perform cell-based experiments to assess the performance of our novel RNA molecules and to conduct the end-point assays for various in vivo experiments (e.g. ELISA, MSD, flow cytometry). These experiments will generate proof of concept across various infectious disease vaccine candidates and other therapeutic programs. We offer an inclusive, dynamic, and fast-paced work environment, where team members have ample opportunity to make meaningful impact on our mission and shape our growing company.

Key responsibilities:

  • Conduct cell-based experiments to assess the expression and immunogenicity of novel RNA constructs
  • Conduct various immunological assays such as ELISA, MSD, western blots, flow cytometry, and RT-qPCR
  • Conduct various immunological assays such as ELISA, Flow Cytometry, ELISpot and ICS
  • Maintain detailed record of experimental protocols and data in electronic lab notebook.
  • Collaborate across research teams to facilitate the success of programs.

Qualifications:

  • B.S. or M.S. in immunology / virology / cellular biology or related field with 4-6 or 2-4 years of relevant experience, respectively.
  • Hands on experience with mammalian cell culture, ELISA and flow cytometry is required.
  • Experience with western blots and/or RT T -qPCR is highly desirable.
  • Experience in vaccines or cell therapies is a plus.
  • Ability to troubleshoot and analyze data.
  • Ability to adapt to increasing scope and complexity of work.

by Jobble

#J-18808-Ljbffr

  • Boston, United States Brigham and Women's Hospital Full time

    Research Assistant I, Infectious Disease-(3287159) Description Working under the supervision of a Principal Investigator and Research Coordinator and following established policies and procedures, assists with clinical research studies. May be responsible for the following activities: recruiting and evaluating patients for studies; collecting and...


  • Boston, United States Brigham and Women's Hospital Full time

    Working under the supervision of a Principal Investigator and Research Coordinator and following established policies and procedures, assists with clinical research studies. May be responsible for the following activities: recruiting and evaluating patients for studies; collecting and organizing patient data; scheduling patients for study visits;...


  • Boston, MA, United States Tufts Medicine Full time

    Tufts Medical Center seeks a full-time Academic Infectious Disease specialist at the Associate or Professor level to serve as the next  Chief of the Division of Geographic Medicine and Infectious Disease.  The successful candidate will provide innovative administrative, clinical, research and educational leadership for the Divisions expanding academic...


  • Boston, United States Tufts Medicine Full time

    Tufts Medical Center seeks a full-time Academic Infectious Disease specialist at the Associate or Professor level to serve as the next Chief of the Division of Geographic Medicine and Infectious Disease. The successful candidate will provide innovative administrative, clinical, research and educational leadership for the Divisions expanding academic...


  • Boston, United States Partners Healthcare System Full time

    GENERAL SUMMARY/ OVERVIEW STATEMENT: The Lemieux laboratory in the MGH Division of Infectious Diseases and the MGH Sexual Health Clinic are developing new diagnostic assays for infectious diseases and are seeking a talented and motivated Clinical Research Assistant who can play a central role in this effort. The Research Assistant will work on a variety of...


  • Boston, United States Partners Healthcare System Full time

    We are looking for a highly specialized Research Specialist with an MD and experience in clinical bioinformatics and single-cell analysis. The applicant will help develop new methods and technologies for HIV research advancement. Research experience in single-cell analysis and virology are preferred. PRINCIPAL DUTIES AND RESPONSIBILITIES: * Use...

  • Research Associate

    1 month ago


    South Boston, United States Tufts University Full time

    OverviewThe faculty in MBM are united by a common interest in the biology of microbes (bacteria, fungi, viruses, and parasites) and the effects of microbes on human and animal hosts. The microbial pathogens program studies microorganisms that cause infectious diseases, with emphasis on rigorous analysis of these pathogens and the immune responses that...


  • Boston, MA, United States Tufts Medicine Full time

    Tufts Medical Center seeks a full-time Academic Infectious Disease specialist at the Associate or Professor level to serve as the next  Chief of the Division of Geographic Medicine and Infectious Disease.  The successful candidate will provide innovative administrative, clinical, research and educational leadership for the Divisions expanding academic...

  • Research Technician

    4 weeks ago


    Boston, Massachusetts, United States Tufts University Full time

    Overview: The faculty in MBM are united by a common interest in the biology of microbes (bacteria, fungi, viruses, and parasites) and the effects of microbes on human and animal hosts. The microbial pathogens program studies microorganisms that cause infectious diseases, with emphasis on rigorous analysis of these pathogens and the immune responses that...


  • Boston, United States Partners Healthcare System Full time

    The Division of Global Health Equity (DGHE) fosters the support and coordination of training, research, and service to reduce disparities in disease burden to improve treatment outcomes both at home and abroad. The Division focuses on infectious diseases as well as non-infectious diseases and other health problems that disproportionately affect populations...

  • PUBLIC HEALTH NURSE

    3 weeks ago


    Boston, MA 02298, USA, United States Boston Public Health Commission Full time

    * Carries out communicable disease surveillance, prevention, and control measures for the City of Boston.* Investigates reports of communicable diseases including pathogens of public health importance, reported outbreaks, or other situations of public health concern, including emerging pathogen events.* Conducts field investigations (including home and site...


  • Boston, United States Massachusetts General Hospital Full time

    Licensed Practical Nurse (LPN), Infectious Disease - 5,000 Sign On Bonus-(3261361) Description GENERAL SUMMARY/ OVERVIEW STATEMENT: The LPN is a licensed nurse who participates in the plan of care to provide competent, compassionate and individualized nursing care to patients and their families – as developed by a registered nurse, nurse...


  • Boston, United States Magnet Biomedicine Full time

    Principal Research Associate/Associate Scientist, Cell Biology About Magnet Biomedicine Magnet Biomedicine is a fast-paced, collaborative, venture-backed startup developing rational approaches to molecular glue discovery. Magnet's TrueGlueTM Discovery Platform enables the discovery and development of fit-for-purpose molecular glue strategies to target a...


  • Boston, United States Partners Healthcare System Full time

    GENERAL SUMMARY/ OVERVIEW STATEMENT: The mission of our laboratory is to improve the quality of life for patients with celiac disease and other gluten-related disorders. The successful candidate will serve as a Clinical Research Coordinator in our center and gain interdisciplinary research experience through assisting with the conduct and management of...


  • Boston, MA, United States Mass General Brigham Full time

    DescriptionGENERAL SUMMARY/ OVERVIEW STATEMENT:The Clinical Research Associate Manager works under direct supervision of a more experienced manager. The Clinical Research Associate Manager provides first-line supervision to Clinical Research Coordinators (CRC) and oversees the day-to-day operations of the staff while maintaining some CRC responsibilities and...


  • Boston, United States Boston Childrens Hospital Full time

    Job Posting DescriptionThe Boston Children's Hospital Infectious Diseases (ID) outpatient practice provides outpatient consultative evaluation and treatment to children and adolescents with any infectious disease. We are seeking a highly motivated, highly organized, detail oriented individual who is a self-starter and able to multitask. Previous healthcare...


  • Boston, MA 02298, USA, United States Boston Medical Center Full time

    POSITION SUMMARY:The registered nurse, adheres to the rules and regulations of the Massachusetts Board of Registration in Nursing. is primarily responsible for professional performance and direct patient care. The role encompasses nursing assessment, diagnosis, planning, intervention, evaluation, and coordination of care for patients and their families...


  • Boston, United States Mass General Hospital, Harvard Medical School Full time

    Postdoctoral Research Fellow Position in Light-Based Antimicrobial Therapy The Wellman Center for Photomedicine at Massachusetts General Hospital (MGH) is pleased to announce a Postdoctoral Research Fellow position in the area of light-based therapy for infectious diseases. This position will be appointed through Harvard Medical School (HMS) at the rank...


  • Boston, Massachusetts, United States Mass General Hospital, Harvard Medical School Full time

    Postdoctoral Research Fellow Position in Light-Based Antimicrobial TherapyThe Wellman Center for Photomedicine at Massachusetts General Hospital (MGH) is pleased to announce a Postdoctoral Research Fellow position in the area of light-based therapy for infectious diseases. This position will be appointed through Harvard Medical School (HMS) at the rank of...


  • Boston, United States Mass General Brigham Full time

    Licensed Practical Nurse (LPN), Infectious Disease - 5,000 Sign On Bonus-(3261361) Description GENERAL SUMMARY/ OVERVIEW STATEMENT: The LPN is a licensed nurse who participates in the plan of care to provide competent, compassionate and individualized nursing care to patients and their families – as developed by a registered nurse, nurse...