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Sr. Principal Chemist â Analytical Chemistry

2 months ago

Indianapolis, United States Eli Lilly and Company Full time

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. Weâre looking for people who are determined to make life better for people around the world.

The Bioproduct Research and Development (BR&D) organization delivers new medicines to patients through the development and commercialization of insulins, peptides, oligonucleotides, monoclonal antibodies, novel therapeutic proteins, and gene therapy systems. BR&D is a multidisciplinary group with deep technical expertise that works collaboratively with our discovery and manufacturing colleagues. Located in Indianapolis, IN, scientists have full access to Lillyâs deep pharmaceutical development expertise and engineering capabilities.    In this role, you will be part of a diverse team of analytical chemists, pharmaceutical scientists, and engineers delivering product and process understanding across a broad range of platforms.  Ideal candidates will possess experience across multiple analytical techniques, demonstrate an aptitude in technical problem-solving, and be motivated to work both independently and collaboratively in a dynamic environment.

Position Responsibilities:

Top candidates for this position will be expected to:

  • Enable the design, development, and implementation of analytical methodologies for the characterization and analysis of cell and gene therapy products.

  • Contribute to the establishment of robust control strategies through generation of data, development of analytical methods, design and execution of stability strategies.

  • Engage with scientists across development and manufacturing as well as through collaboration with external development partners to design and implement control strategies for projects at various stages of development.

  • Responsible for evaluating and/or implementing new analytical technologies/methods to advance Lillyâs current analytical capabilities.

    • Spearhead new initiatives to improve existing scientific processes within the organization and across the company.

    • Identify and exploit new scientific concepts, strong problem-solving skills, and be self-motivated to contribute across multiple projects.

    • Demonstrate strong written and verbal communication skills to speak to both technical and business-related implications of your work.

    • May supervise other BS/MS analytical scientists supporting BR&D analytical development.

      Basic Qualifications:

    • MS with 3+ years of drug development experience, or BS with 8+ years of drug development experience.

      Additional Skills/Preferences:

    • Experience with analytical control strategy development from pre-FHD to commercial launch.

  • Demonstrated proficiency with drug development for cell and gene therapy products.

Experience with chromatographic separations (reversed phase chromatography, ion exchange chromatography, size exclusion chromatography), capillary electrophoresis, spectroscopic methods, and other methods for the analysis of cell and gene therapy products.

Knowledge of ddPCR and ELISA based methods for analysis of cell and gene therapy products.

Effective oral and written communication skills.

Demonstration of scientific and people leadership skills.

Demonstrate proficiency in multiple modes of chromatography, mass spectrometry, optical spectroscopy, instrument engineering, or other analytical technologies.

Experience with data interpretation, including the application of chemometrics, multivariate modeling, and other data manipulation tools.

Learning agility and demonstrated ability to apply technical knowledge to improve the understanding of chemical systems or improve analytical techniques.

Ability to balance multiple activities, prioritize evolving project needs, and handle ambiguity.

Must be able to work productively in an interdisciplinary team environment.

Additional Information:

Travel: 0 to 15%

Potential exposure to chemicals, allergens, and loud noises.

Position Local: Indianapolis, IN; Lilly Technology Center-North (LTC-N)

Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively âLillyâ) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( Lilly_Recruiting_Compliance@lists.lilly.com ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Womenâs Network, Working and Living with Disabilities. Learn more about all of our groups.

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