Scientist II
3 weeks ago
Scientist II - AKTA and Protein Purification
South San Francisco, CA
6+ month initial contract
Hourly Pay Rate: $52-56/hr (medical benefits available at a cost)
Orion Group is seeking to hire a Scientist for our global pharmaceutical client's Biologics Protein Purification Team. Join a talented and diverse team team in developing purification processes for GMP applications. In this laboratory based position, the candidate will provide hands-on support for purification development and process scale-up activities in a collaborative and dynamic environment to help advance novel therapies to human clinical studies.
Responsibilities include:
* Development, optimize, and scale-up purification processes for biologics candidates to support early and late stage development
* Innovate, develop, optimize, and scale-up purification processes
* Conceive and evaluate novel advanced separation technologies and techniques
* Proactively seek out new information in the literature and incorporate this into individual project(s) as well as the overall program
* Seize opportunities to pursue project relevant leads that are in line with the group's strategy.
* Maintain a high level of productivity in the lab.
* Transfer processes to GMP manufacturing for clinical material production
* Work with contract labs and carry out viral clearance studies
* Write technical publications, reports, presentations, and regulatory filings including publishing research in peer-reviewed journals and presenting work at scientific conferences
* Work efficiently, collaboratively, and cross-functionally toward project timelines and goals
* Participate on cross-functional project teams
* Mentor and train junior scientists
Qualifications:
* Bachelor's Degree or equivalent education and typically 3-5 years of experience, MS or equivalent education and typically 3-5 years of experience, PhD and typically 3+ years of experience
* Must have hands on experience in protein purification including chromatography separations and filtration operations
* Able to independently design, execute, and interpret laboratory experiments to answer scientific questions
* Must be forward-thinking and be able to lead and contribute to scientific/technical discussions
* Able to independently learn, understand and execute novel/advanced scientific techniques
* Must have excellent attention to detail and ability to keep detailed written records
* Able to author publications, technical reports, regulatory documents, and presentations
* Has strong communication skills including verbal, written, and scientific data presentation
* Has good understanding of biochemistry and bioprocess engineering concepts
* Able to work collaboratively within and outside of the group
* Has proficiency with Microsoft Office software, ability to learn new software applications
Preferred Skills:
* PhD with at least 3+ years experience is highly preferred for this role
* Proficient in writing methods and operating AKTA chromatographic instruments (such as AKTA Avant, AKTA Purifier, AKTA Pure, AKTA Ready or similar)
* Has a strong understanding of analytical techniques, such as HPLC and ELISA
* Has hands on experience with monoclonal antibody or antibody-like molecule purification at GMP, pilot and/or laboratory scale
* Demonstrated scientific aptitude through authorship of peer-reviewed publications
* Has a strong understanding of statistical analysis
Our role in supporting diversity and inclusion
As an international workforce business, we are committed to sourcing personnel that reflects the diversity and values of our client base but also that of Orion Group. We welcome the wide range of experiences and viewpoints that potential workers bring to our business and our clients, including those based on nationality, gender, culture, educational and professional backgrounds, race, ethnicity, sexual orientation, gender identity and expression, disability, and age differences, job classification and religion. In our inclusive workplace, regardless of your employment status as staff or contract, everyone is assured the right of equitable, fair and respectful treatment.
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