senior backend python developer jobs in Philadelphia

727 senior backend python developer job listings in United States. Find daily updated positions from leading job boards.


  • Philadelphia, PA, PA, United States Jazz Pharmaceuticals Remote Full-time

    **If you are a current Jazz employee please apply via the Internal Career site.** Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases — often with limited or no therapeutic options. We...

  • AI/ML Engineer

    2 days ago


    Philadelphia, PA, United States Vanguard Full-time

    ResponsibilitiesDesign, prototype, and implement agentic systems for IT automation and resilience using LLMs and agent frameworks Develop multi-agent workflows and coordinate agent collaboration for complex tasks.Build and optimize retrieval-augmented generation pipelines for knowledge-driven agents.Contribute to the development and testing of robust,...

  • 2026

    22 hours ago


    Philadelphia, Pennsylvania, United States Flores Financial Services Full-time

    VP, Engineering – HR Technology (Enhanced to Emphasize HR Data Expertise) The successful candidate is expected to: Lead and build full‑stack, enterprise‑grade platforms using Python, Java, Spring Boot, ReactJS, and SQL/NoSQL databases, while remaining hands‑on with code. Own and drive Low‑Level Design (LLD) and High‑Level...

  • AI/ML Engineer

    23 hours ago


    Philadelphia, Pennsylvania, United States The Vanguard Group Full-time

     ResponsibilitiesDesign, prototype, and implement agentic systems for IT automation and resilience using LLMs and agent frameworks Develop multi-agent workflows and coordinate agent collaboration for complex tasks.Build and optimize retrieval-augmented generation pipelines for knowledge-driven agents.Contribute to the development and testing of robust,...


  • Philadelphia, PA, United States Logging-In Full-time

    Job Title; RDK-B Triage EngineerLocation: Philadelphia, PA Job Description: Your daily tasks:Ensure timely and high-quality software releases across diverse devices by proactively monitoring metrics and alerting systems. Promptly respond to critical field issues, identify root causes, and implement effective mitigation strategies.Troubleshoot E2E issues in...

  • Actuarial Consultant

    23 hours ago


    Philadelphia, Pennsylvania, United States Penna Lumbermens Mut Ins Co Full-time

      Position Summary: The Actuarial Consultant is responsible for working with the Major Account Unit and providing guidance on large account pricing and program structures. This position, at a macro level, will provide recommendations and actuarial support for line of business rate changes and associated actuarial state filings. The Actuarial Consultant...

  • Solutions Architect

    23 hours ago


    Philadelphia, Pennsylvania, United States Databricks Full-time $180,000 - $247,500 Contract

    FEQ227R273While candidates in the listed location(s) are encouraged for this role, candidates in other locations will be considered. #CMEG As a Solutions Architect, you will lead the technical strategy for your customers — owning architecture discussions, driving platform adoption, and serving as a trusted advisor to customer technical leads and...


  • Philadelphia, PA, United States BlueWater Federal Solutions, Inc. Full-time

    Overview Bluewater Federal is looking for a Cybersecurity Analyst to support the Naval Surface Warfare Center (NSWC), Philadelphia, PA As a Cybersecurity Analyst, you will support in the collection, organization, and analysis of network and system data to identify and address emerging risks, supporting Navy RMF compliance and continuous monitoring...


  • Philadelphia, PA, United States Calance Full-time

    Location:Philadelphia, PA,Kubernetes Platform Engineer Voice Services ModernizationPosition SummaryThe Kubernetes Platform Engineer Voice Services Modernization is responsible for designing, deploying, automating, and operationalizing cloud-native infrastructure for mission-critical voice applications. This role focuses on transforming traditional VM-based...


  • Philadelphia, PA, United States Creditly Corp Full-time

    Company Credit Genie is a mobile-first financial wellness platform designed to help individuals take control of their financial future. We leverage artificial intelligence to provide personalized insights and are building a financial ecosystem by offering tools and services that provide instant access to cash, and building credit. Our goal is to empower...


  • Philadelphia, PA, United States Amtrak Full-time

    As we move America’s workforce toward the future, our goal is to connect businesses and communities across the country. The safety of our passengers, our more than 20,000 colleagues, the public and our operating environment is our priority, and the success of our railroad is due to your efforts Our values of ‘Do the Right Thing, Excel Together and Put...


  • Philadelphia, Pennsylvania, United States The O'Connor Group Full-time $90,000 - $140,000 Contract

     We are partnering with Ghost Robotics and have announced the search for a Robotics Software Engineer (Controls)Description  Ghost Robotics is a robotics company building autonomous systems that operate in complex, dynamic environments. Our perception stack enables our robots to understand, localize, and navigate the world in real time, and we place a...

  • Sr Data Scientist

    11 hours ago


    Philadelphia, Pennsylvania, United States Elsevier Full-time

    Senior Data Scientist What if your next AI model could help accelerate a medical breakthrough, uncover a critical scientific insight, or help researchers solve some of humanity's greatest challenges ?At Elsevier, data science is about far more than algorithms and model performance. It is about applying advanced AI to help researchers, clinicians, educators,...

  • Data Software Engineer

    22 hours ago


    Philadelphia, Pennsylvania, United States ADTM Adenza Technology de Mexico S de RL de CV Full-time $10,000 Temporary

    The Role As a Senior Software Developer (Data Engineering) you'll play a critical role in building and maintaining the data solutions that power regulatory reporting across U.S. equity and options markets. You'll thrive in this position if you're analytical, solutions-oriented, and collaborative — someone who takes ownership of complex technical problems...


  • Philadelphia, Pennsylvania, United States Artech Information System Full-time

    Company DescriptionArtech is the 10th Largest IT Staffing Company in the US, according to Staffing Industry Analysts' 2012 annual report. Artech provides technical expertise to fill gaps in clients' immediate skill-sets availability, deliver emerging technology skill-sets, refresh existing skill base, allow for flexibility in project planning and execution...


  • philadelphia, pa, United States CyberCoders Full-time

    Remote Sr or Staff Engineer ($150-$230k) Ruby, Rails, Claude Permanently 100% Remote Job Title: Remote Sr or Staff Software EngineerSalary: $150k-$230k Base + Benefits, 401k, PTORequirements: Ruby/Rails or Python/DjangoOur Tech Stack: Ruby/Rails, AWS, React, TypeScript, Ansible, Terraform, CloudFormation, Linux, Postgres We recently closed out Series C...


  • Philadelphia, Pennsylvania, United States Chubb Full-time $183,700 - $240,000 Contract

    DescriptionBy joining Chubb as Principal Data Engineer for our North America Finance & Actuarial and Corporate Data platforms, you'll set the engineering direction for a portfolio of strategic applications that directly underpin financial, actuarial, claims, regulatory, underwriting and executive decision-making across the enterprise. This is a technical...

  • ML OPs Engineer

    11 hours ago


    Philadelphia, Pennsylvania, United States Elsevier Full-time

    About the team, this team that powers Elsevier’s Health platforms: Clinical Key AI, Sherpath AI, and AI-driven automated clinical and content workflows. You will bridge Data Science and Engineering to turn experimental NLP/IR/GenAI models into secure, reliable, and scalable services. Our systems operate over one of the world’s largest medical and...

  • Systems Engineer

    7 hours ago


    Philadelphia, Pennsylvania, United States Grantek Full-time

    From concept to design to execution, be part of the team that gets everyday products to people. Do you want to have an impact on creating products from today’s top brands? Does having a company care about your career today and into the future motivate you? Does an environment where your opinions matter excite you? Are you a natural born tinkerer? If so,...

  • Systems Engineer

    7 hours ago


    Philadelphia, Pennsylvania, United States Grantek Systems Integration Full-time

    Company Description From concept to design to execution, be part of the team that gets everyday products to people. Do you want to have an impact on creating products from today’s top brands? Does having a company care about your career today and into the future motivate you? Does an environment where your opinions matter excite you? Are you a natural...