senior backend python developer jobs in Philadelphia

714 senior backend python developer job listings in United States. Find daily updated positions from leading job boards.

  • Senior AI Engineer

    15 hours ago


    Philadelphia, Kansas, United States Reply Full-time

    Valorem Reply is an award-winning digital transformation firm focused on delivering data-driven enterprise, IT modernization, customer experience, product transformation and digital workplace. Through the expertise of their people and power of Microsoft technologies, they provide hyper-scale and agile delivery of unique digital business services, strategic...

  • Senior DevOps Engineer

    16 hours ago


    philadelphia, pa, United States US Full-time

    About the Role Our client is seeking a skilled Senior DevOps Engineer with a focus on Cloud Automation to join their dynamic team in Philadelphia . You will be responsible for designing, implementing, and managing the infrastructure and automation tools that enable rapid, reliable software delivery. This hybrid role involves collaborating with...

  • Senior Data Scientist

    16 hours ago


    Philadelphia, Pennsylvania, United States Berkley Full-time $150,000 - $200,000 Contract

    Company Details   Driven by a commitment to collaboration, DNA partners with our customers and Operating Units by providing comprehensive solutions that not only address the challenge at hand, but proactively plan for the “What’s Next” in our industry and beyond.  Our mission is to drive transformation and provide exceptional...


  • Philadelphia, Pennsylvania, United States Elsevier Full-time $95,300 - $158,800 Contract

    Senior Software Engineer AI Agents · Wellsheet at ElsevierAbout Wellsheet at Elsevier: Wellsheet is a clinical decision support platform used by more than 20,000 providers across 100+ hospitals. We embed directly in the EHR (Epic, Cerner, Athena) and put AI-generated clinical context in front of clinicians at the bedside. In 2026 Wellsheet became part of...

  • Senior Data Scientist

    16 hours ago


    Philadelphia, Pennsylvania, United States Elsevier Full-time $95,300 - $158,800 Contract

    Senior Data ScientistAI for Science, Research Intelligence & Knowledge DiscoveryBuild AI That Helps Advance Human KnowledgeWhat if your next AI model could help accelerate a medical breakthrough, uncover a critical scientific insight, or help researchers solve some of humanity's greatest challenges?At Elsevier, data science is about far more than algorithms...


  • Philadelphia, PA, Philadelphia County, PA; Pennsylvania, United States Planet Full-time

    Planet designs, builds, and operates the largest constellation of imaging satellites in history. This constellation delivers an unprecedented dataset of empirical information via a revolutionary cloud-based platform to authoritative figures in commercial, environmental, and humanitarian sectors. We are both a space company and data company all rolled into...


  • Philadelphia, Pennsylvania, United States CoreWeave Full-time $153,000 - $204,000 Contract

    CoreWeave is The Essential Cloud for AI™. Built for pioneers by pioneers, CoreWeave delivers a platform of technology, tools, and teams that enables innovators to build and scale AI with confidence. Trusted by leading AI labs, startups, and global enterprises, CoreWeave combines superior infrastructure performance with deep technical expertise to...


  • Philadelphia, PA, Philadelphia County, PA; Pennsylvania, United States Elsevier Full-time

    Senior Data Scientist AI for Science, Research Intelligence & Knowledge Discovery Build AI That Helps Advance Human Knowledge What if your next AI model could help accelerate a medical breakthrough, uncover a critical scientific insight, or help researchers solve some of humanity's greatest challenges? At Elsevier, data science is about far more than...


  • Philadelphia, Pennsylvania, United States GTT Full-time $160,000 Contract

    Senior Machine Learning Engineer Location: Philadelphia, PA Onsite Flexibility: Onsite Job Details Position Type: Right to Hire (Contract-to-Hire)Pay / Salary: $160,000 / Year (USD)Work Authorization: Applicants must be authorized to work for ANY employer in the U.S. We are unable to sponsor or take over sponsorship of an employment Visa at this time. Job...


  • Philadelphia, Pennsylvania, United States T-Mobile Full-time $116,500 - $210,100 Contract

    At T-Mobile, we invest in YOU! Our Total Rewards Package ensures that employees get the same big love we give our customers. All team members receive a competitive base salary and compensation package - this is Total Rewards. Employees enjoy multiple wealth-building opportunities through our annual stock grant, employee stock purchase plan, 401(k), and...

  • Senior Data Scientist

    16 hours ago


    Philadelphia, Pennsylvania, United States RELX Full-time $95,300 - $158,800 Contract

    Senior Data ScientistAI for Science, Research Intelligence & Knowledge DiscoveryBuild AI That Helps Advance Human KnowledgeWhat if your next AI model could help accelerate a medical breakthrough, uncover a critical scientific insight, or help researchers solve some of humanity's greatest challenges?At Elsevier, data science is about far more than algorithms...


  • Philadelphia, Pennsylvania, United States Perpay Full-time $160,000 Contract

    About Us: Perpay is a certified B Corp and Philadelphia’s most impactful growth-stage startup. We are driven by a mission to significantly improve the financial stability of everyday Americans. For the past decade, we have established strong product-market fit and a profitable, efficient operating model across a suite of products, positioning Perpay as the...


  • Philadelphia, Pennsylvania, United States Perpay Full-time $160,000 Contract

    About Us: Perpay is a certified B Corp and Philadelphia’s most impactful growth-stage startup. We are driven by a mission to significantly improve the financial stability of everyday Americans. For the past decade, we have established strong product-market fit and a profitable, efficient operating model across a suite of products, positioning Perpay as the...

  • Senior Data Scientist

    15 hours ago


    Philadelphia, Pennsylvania, United States ADTM Adenza Technology de Mexico S de RL de CV Full-time $95,000 - $166,000 Contract

    When you work at Nasdaq, you’re working for more open and transparent markets so that more people can access opportunities. Connections can be made, jobs can be created, and communities can thrive. We want all our employees to have access to opportunity, too. That means planning for career growth, ensuring you have the tools you need, and promoting an...


  • Philadelphia, PA, United States Deloitte Full-time

    Position Summary Join Deloitte’s Cyber practice as a Cyber SecOps Senior Consultant and help clients navigate an evolving threat landscape through scalable, resilient security operations solutions. In this hands-on role, you will support high-visibility engagements focused on Google SecOps, threat detection engineering, and...


  • Philadelphia, Pennsylvania, United States Cabaletta Bio Full-time

    Position: Senior Infrastructure Engineer   Philadelphia, PA (Hybrid) Cabaletta Bio (Nasdaq: CABA) is a clinical-stage biotechnology company focused on developing and launching the first curative targeted cell therapies designed specifically for patients with autoimmune diseases. The CABA™ platform encompasses two complementary strategies which aim to...


  • Philadelphia, Pennsylvania, United States Proscia Full-time

    About Proscia Proscia is revolutionizing pathology, the last major frontier in healthcare to embrace digital. As a leader in pathology AI software, we are empowering pathologists and scientists to transition from traditional microscope-based workflows to digital, AI-driven approaches, unlocking new possibilities in precision medicine. The digital pathology...


  • Philadelphia, Pennsylvania, United States Saicon Full-time

    About the role We build predictev™, an AI-driven audience intelligence platform used by pharma brand and marketing teams. The platform is live, the client list is growing, and the asks change weekly — a new brand, a new data cut, a new agent capability needed with a short turnaround. We are looking for a senior engineer who can land inside an existing...

  • Senior AI/ML Engineer

    16 hours ago


    Philadelphia, New York, United States QTech Full-time $45 - $50 Permanent

    Job: Senior AI/ML Engineer Location: Boston, MA, Hartford, CT, Princeton, NJ, Philadelphia, PA, New York City, NY Contact: 12+ Months Looking for W2 candidates. No C2C Responsibilities: Design, develop, and deploy AI/ML models for enterprise applications. Build scalable machine learning pipelines and data preprocessing workflows. Develop and optimize LLM,...

  • Senior Data Engineer

    15 hours ago


    Philadelphia, Pennsylvania, United States Universal Music Full-time $68,100 - $179,000 Contract

    We are UMG, the Universal Music Group. We are the world’s leading music company. In everything we do, we are committed to artistry, innovation and entrepreneurship. We own and operate a broad array of businesses engaged in recorded music, music publishing, merchandising, and audiovisual content in more than 60 countries. We identify and develop recording...