senior backend python developer jobs in Philadelphia

735 senior backend python developer job listings in United States. Find daily updated positions from leading job boards.


  • Philadelphia, PA, Philadelphia County, PA; Pennsylvania, United States T H E O R I Full-time

    We’re looking for an experienced backend engineer to help build and scale the next generation of AI-driven cybersecurity platforms at Theori. You’ll play a key role in architecting and implementing core backend systems that power Xint, our autonomous penetration testing framework.   This is a foundational role in our NA engineering team—ideal for...


  • Philadelphia, PA, Philadelphia County, PA; Pennsylvania, United States Swiftly Full-time

    Company Description Swiftly is on a mission to help cities move more efficiently. We are the leading transit data platform for agencies to share real-time passenger information, manage day-to-day operations, and improve service performance. Today, over 200 transit agencies in 12 countries – including LA Metro, MARTA, SEPTA, and MBTA – rely on Swiftly...


  • Philadelphia, Pennsylvania, United States City of Philadelphia Full-time $105,000 - $110,000 Contract

    Company Description A best-in-class city that attracts best-in-class talent, Philadelphia is an incredible place to build a career. From our thriving arts scene and rich history to our culture of passion and grit, there are countless reasons to love living and working here. With a workforce of over 30,000 people, and more than 1,000 different job...

  • Jr Data Scientist

    3 weeks ago


    Philadelphia, Pennsylvania, United States TalentOla Full-time

    Role: Healthcare Data Scientist Location: Remote   Key Responsibilities: Assist in building and training machine learning models using structured and unstructured healthcare data. Support data preprocessing, feature engineering, and model evaluation tasks. Collaborate with senior ML engineers, data scientists, and data engineers to implement scalable...

  • Automation Developer

    3 weeks ago


    Philadelphia, Pennsylvania, United States Arctiq Remote Full-time

    Company Overview:Arctiq is a global, intelligence-driven technology services company delivering professional and managed services across Hybrid Cloud Infrastructure, Networking & Connected Experiences, Cybersecurity, Data & AI, Autonomous Operations & Intelligence, and Enterprise Service Management. We help organizations operate, secure, and modernize...

  • Data Engineer

    3 weeks ago


    Philadelphia, PA, PA, United States Turnberry Solutions Remote Full-time

    **Duration:** 2+ Months **Location:** PA-Philadelphia, 100% Remote **Overview:** Every Turnberry consultant belongs to a practice, an internal group of consultants and leaders with shared experience and expertise. Each of these practices aligns to one of the core services Turnberry offers to clients. As a Data Engineer, you will join Turnberry's...

  • Application Developer

    3 weeks ago


    Philadelphia, Pennsylvania, United States NBME Full-time $114,982 - $145,000 Contract

    POSITION OVERVIEW NBME is seeking an Application Developer to join our Product Engineering team. In this role, you'll lead the design and development of innovative software solutions that impact medical education globally. You'll collaborate in an agile environment, mentor team members, and work across the full stack to ensure our systems are secure,...


  • Philadelphia, PA, PA, United States Calance Full-time

    Kubernetes Platform Engineer – Voice Services Modernization **Our Client:** A leading provider of mission-critical voice communication solutions, is seeking a **Kubernetes Platform Engineer – Voice Services Modernization** . This role offers the chance to lead a high-impact cloud-native transformation initiative, modernizing legacy voice infrastructure...


  • Philadelphia, PA, PA, United States Perpay - Career's Page Full-time

    ### **About Us:** Perpay is a certified B Corp and Philadelphia's most impactful growth-stage startup. We are driven by a mission to significantly improve the financial stability of everyday Americans. For the past decade, we have established strong product-market fit and a profitable, efficient operating model across a suite of products, positioning Perpay...

  • Data Architect

    3 weeks ago


    Philadelphia, PA, PA, United States Turnberry Solutions Remote Full-time

    **Duration:** 2+ Months **Location:** PA-Philadelphia, 100% Remote **Overview:** Every Turnberry consultant belongs to a practice, an internal group of consultants and leaders with shared experience and expertise. Each of these practices aligns to one of the core services Turnberry offers to clients. As a Data Architect, you will join Turnberry's...

  • Junior Linux

    3 weeks ago


    Philadelphia, PA, PA, United States Largeton Group Full-time $45 - $50 Contract

    **Job Summary (Junior Linux / Cloud Systems Engineer): Philadelphia, PA** - Position: 12-Month Contract (Potential for extension or permanent conversion) - Location: Greater Philadelphia, PA (Hybrid; 3 days onsite: Tues/Wed/Thurs; must currently live within commuting distance) - Background Check: 10-year screen, drug test, and fingerprinting required **Key...


  • Philadelphia, PA, PA, United States Perpay Inc. Full-time

    **About Us:** Perpay is a certified B Corp and Philadelphia's most impactful growth-stage startup. We are driven by a mission to significantly improve the financial stability of everyday Americans. For the past decade, we have established strong product-market fit and a profitable, efficient operating model across a suite of products, positioning Perpay as...


  • Philadelphia, Pennsylvania, United States Pivotal Solutions, Inc. Full-time

    Position Overview: We are seeking an experienced Senior Backend Engineer with strong Java expertise to join our growing engineering team. The ideal candidate will have a deep understanding of building scalable, resilient, and high-performance backend systems. This individual will collaborate closely with cross-functional teams, helping shape the future of...


  • Bala Cynwyd (Philadelphia Area), Pennsylvania, United States Susquehanna International Group, LLP Full-time

    Overview At Susquehanna, quantitative researchers tackle challenging data and algorithmic problems that inform decision-making in global financial markets. Their work spans statistical inference, optimization, market microstructure, simulation, forecasting, and large-scale data analysis, drawing on a broad quantitative toolkit to develop new...


  • Bala Cynwyd (Philadelphia Area), Pennsylvania, United States Susquehanna International Group, LLP Full-time

    Overview As a quantitative strategy developer, you'll work in a computationally intensive role that will allow you to use your strong technical skills to solve problems at the intersection of trading, quantitative analysis, and technology. You will have the chance to work on challenging problems across our trading teams in areas such as signal...


  • Philadelphia, PA, PA, United States Proscia Full-time

    Reports to: Vice President Solutions & Services Location: Remote USA **About Proscia** Proscia is revolutionizing pathology, the last major frontier in healthcare to embrace digital. As a leader in pathology AI software, we are empowering pathologists and scientists to transition from traditional microscope-based workflows to digital, AI-driven...


  • Philadelphia, Pennsylvania, United States GSK Full-time

    Job Title: Sr Manager, Oncology Commercial AnalyticsJob Purpose:Sr Manager, Oncology Commercial Analytics is a high-impact role embedded within GSK's Oncology Business Unit, partnering directly with brand and BU leadership to translate complex commercial data into decisions that drive portfolio performance. Responsibilities span customer segmentation and...


  • Philadelphia, Pennsylvania, United States Philadelphia Phillies Full-time

    Title: Quantitative Analyst AssociateDepartment: Baseball Research & Development Reports to: Lead/Senior Quantitative AnalystStatus: Hourly Part-Time Seasonal Position Overview: As a Quantitative Analyst (QA) Associate, you help shape The Phillies Baseball Operations strategies by processing, analyzing, and interpreting large and complex data. You do more...


  • Philadelphia, PA, PA, United States Comcast Full-time

    Comcast brings together the best in media and technology. We drive innovation to create the world's best entertainment and online experiences. As a Fortune 50 leader, we set the pace in a variety of innovative and fascinating businesses and create career opportunities across a wide range of locations and disciplines. We are at the forefront of change and...


  • Philadelphia, Pennsylvania, United States GSK Full-time

    Position Summary:You will lead and transform GSK’s Master Data Management (MDM) capability for the US organization — owning the vision, architecture, and operating model that deliver a single, trusted view of our most critical master data. Customer mastering (spanning Healthcare Professionals, Accounts, and Patients) is at the heart of this role, and...