Scientist or Senior Scientist, Protein Biochemistry
1 month ago
Scientist or Senior Scientist, Protein Biochemistry
Boston, MA
Please only apply if you have biotech or biopharma industry experience.
We are seeking an experienced Scientist/Senior Scientist to join our client’s Protein Discovery team. The ideal candidate will have hands-on expertise in protein purification and a deep understanding of protein biochemistry. This role will support the development of cutting-edge immune-modulatory therapies, with an emphasis on therapeutic proteins for oncology and autoimmune indications. The position offers a strong opportunity for growth within a fast-paced, collaborative, and evolving drug discovery environment.
Primary Responsibilities
- Perform transient expression of engineered proteins, including Fc-fusion proteins, in mammalian cell systems.
- Carry out protein purification using various chromatography techniques, such as affinity, ion-exchange, and size-exclusion chromatography.
- Execute protein characterization and quality control through a range of analytical assays, including SE-HPLC, SDS-PAGE, UV-Vis spectroscopy, and ELISA.
- Conduct buffer optimization and screening to determine the best formulations for therapeutic proteins.
- Support the optimization of protein conjugation and purification processes.
- Analyze experimental data, generate insights, and recommend follow-up experiments.
- Communicate findings clearly through written reports and oral presentations to cross-functional teams.
- Work closely with the protein production team to improve workflows, troubleshoot issues, and provide hands-on assistance as necessary.
- Keep accurate and detailed records of laboratory work and experimental data.
- Ensure the proper maintenance and operation of laboratory instruments relevant to protein production and analysis.
Qualifications
- B.S. or M.S. with 7-8 years of industry experience, or a Ph.D. with 1-2 years of industry experience in a Biotech / Biopharma setting.
- Proven hands-on experience in protein purification and a solid understanding of protein biochemistry.
- Proficiency with instrumentation such as AKTA is essential.
- Expertise with bioanalytical techniques, including HPLC, DSC, SEC-MALS, DSF, and other similar tools.
- Experience in designing and executing biochemical and biological assays.
- Experience in protein conjugation chemistry is a significant plus.
- Scientific understanding of experimental design and underlying principles.
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boston, United States HireMinds Full timeScientist or Senior Scientist, Protein Biochemistry Boston, MAPlease only apply if you have biotech or biopharma industry experience.We are seeking an experienced Scientist/Senior Scientist to join our client’s Protein Discovery team. The ideal candidate will have hands-on expertise in protein purification and a deep understanding of protein biochemistry....
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boston, United States HireMinds Full timeScientist or Senior Scientist, Protein Biochemistry Boston, MAPlease only apply if you have biotech or biopharma industry experience.We are seeking an experienced Scientist/Senior Scientist to join our client’s Protein Discovery team. The ideal candidate will have hands-on expertise in protein purification and a deep understanding of protein biochemistry....
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