Sr. Scientist, Protein Biochemistry

4 days ago

Boston, United States HireMinds Full time

Sr. Scientist, Protein Biochemistry

Location: Boston, Massachusetts


HireMinds is representing a clinical-stage biopharmaceutical client that is leading the way in developing biologics. Our clients approach allows them to selectively engage and modulate disease-specific T cells, aiming to transform the treatment landscape for cancer, autoimmune, and inflammatory diseases. Located in an exciting new lab space in Boston's vibrant life sciences corridor they have a collaborative team with hands-on leadership that is present and invested in the team's success. Reach out to HireMinds Biotech team or apply today to learn more


You'll Be Responsible For:

  • In this role you'll work as a Scientist or Senior Scientist in a Protein Discovery team and bring your hands-on skill in protein purification and work in protein characterization.
  • Work on mammalian expression of products including engineered Fc-fusion and recombinant proteins
  • Perform protein purification with affinity, ion exchange (IEX), and size-exclusion chromatography (SEC).
  • Progress programs into downstream testing in Quality Control and characterization utilizing methods including SE-HPLC, SDS-PAGE, UV-Vis spectroscopy, and ELISA.
  • Design and execute buffer screens and assays to optimize formulations of protein therapeutics.
  • Ideally you'll bring experience with the optimization of protein conjugation and purification processes.
  • Present your findings through well-structured documentation and engaging oral presentations to peers and management teams.
  • Manage routine maintenance of instrumentation vital to protein biochemistry and collaborate with vendors when necessary.


You'll Bring With You:

  • B.S. or M.S. in pharmaceutical, biological, or chemical sciences with 7+ years of industry experience, or
  • Ph.D. in a relevant field with 2 years of industrial experience in Biotech or Biopharma.
  • Strong hands-on experience in protein purification and a solid grasp of protein biochemistry.
  • Hands-on experience with instrumentation, including AKTA systems and bioanalytical techniques: HPLC, DSC, SEC-MALS, DSF.
  • Proven ability to design and carry out biochemical or biological assays.
  • Previous experience with protein conjugation chemistry is preferred.


This position offers an extraordinary chance for protein biochemists eager to make a significant impact on drug discovery while expanding their professional skills in a collaborative and innovative setting. Become part of our clients mission to redefine treatment options for patients.

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