Head of Project Management

3 weeks ago

Grafton, United States Siegfried Full time

The Siegfried Group is a global life science company with a network of 13 sites across Europe, the USA, and Asia. Siegfried offers contract development and manufacturing of active pharmaceutical ingredients, intermediates, and drug products. Siegfried employs over 3,700 people and generated sales of 1.3 billion USD in 2023. Siegfried Holding AG is listed on the SIX Swiss Exchange (SIX: SFZN).


Siegfried's Acceleration Hub is the latest addition to the Siegfried network. Located in Grafton (WI), we provide comprehensive support to customers in from early phase pre-clinical and clinical development, through scale up and validation up to and including commercial manufacturing of Drug Substances.


Within this context, we are currently looking to fill the position of Head of Project Management to join a highly motivated, hands-on Site Leadership Team who is ‘all in’, growing to double new chemical entity capacity in the next two years with both facility and technology expansions.


Your responsibilities


In this role you will be responsible for the overall strategy and execution of New Chemical Entities introduction and lifecycle management by providing project management leadership and management for projects evaluated and accepted by the Siegfried Acceleration Hub. This includes internal and external technical transfer projects, product development and potentially commercialization projects, as well as process improvement projects for the Grafton Site. In addition, you will have the chance to lead and further build up the newly set up project management team.


This role is an integral part of the Site Leadership Team and reports directly to the General Manager of the site.


Your tasks


  • Lead and manage cross-functional project teams, coordinating activities across departments to ensure timely, quality, and budget-conscious project delivery from early phase to commercialization.
  • Collaborate closely with Business Development/Sales to secure new clients, support technical evaluations, review proposals, and contribute to customer questionnaires and inquiries.
  • Serve as the primary contact for client projects, including handling project changes (scope, schedule, and budget), preparing necessary documentation, and leading customer communications.
  • Drive internal and external meetings by setting agendas, tracking progress, issuing minutes, and ensuring action items are completed by deadlines.
  • Prepare and update detailed project plans, establish milestones, identify critical issues, and proactively implement solutions to mitigate risks.
  • Oversee project-related customer site visits during bidding and manufacturing, ensuring successful client engagement and satisfaction.
  • Act as a working manager by leading a team of Project Managers, providing direction and supporting their development and project success.


Your profile


  • Master's degree in Organic Chemistry, Engineering, or a related life sciences field required; PhD preferred.
  • 12-15+ years of experience in the pharmaceutical industry, with expertise in project management, matrix management, and team leadership.
  • Deep knowledge of pharmaceutical drug substance development, API manufacturing, Good Manufacturing Practices (GMPs), and ICH standards (e.g., Q7A).
  • Project Management certification (e.g., PMI, PMP) or equivalent experience strongly preferred.
  • Strong leadership skills with the ability to influence, guide, and manage teams to meet project timelines, budget commitments, and desired outcomes.
  • Experience managing multiple projects simultaneously and working directly with clients to exceed expectations.
  • Excellent communication skills, both verbal and written, with the ability to work cross-functionally across diverse teams and cultures.
  • Highly detail-oriented, self-motivated, and capable of working independently with minimal supervision.


Why joining Siegfried in Grafton


  • Employee Share Program
  • 401(k) Match
  • Medical, Dental, and Vision (competitive cost share)
  • Life, Sickness and Accident insurance, and Long-term disability (paid by company)
  • Paid time off and holidays
  • Pregnancy disability and parental leave
  • Buy Up of Life Insurance (optional)


Siegfried USA will explore and provide reasonable accommodations to assist any qualified individual with a disability in performing the essential functions of his/her job.

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