Senior Research Associate/Associate Scientist in Protein Analytics

2 weeks ago


Cambridge, United States Crossbow Therapeutics, Inc Full time

The (Sr) Research Associate/Associate Scientist will join efforts of Antibody Discovery, Protein Engineering and Process Development team to develop safe and effective T-cell engager therapies. The candidate will have an opportunity to contribute to groundbreaking research working with a team of enthusiastic scientists.

Key Responsibilities:


  • Perform protein characterization using multiple biophysical and biochemical techniques (i.e. SEC, HIC, IEX, SDS-PAGE, BLI), as well as other assessment tools.
  • Perform stability assessment of proteins (antibodies and antigens)
  • Support the development, optimization, and troubleshooting of analytical methods for protein characterization.
  • Maintain and troubleshoot analytical equipment.
  • Perform protein purification from bacterial protein expression system and further protein analysis and characterization.
  • Maintain well-organized electronic notebook records of experimental data, author technical protocols and reports, communicate experimental results to the team.
  • Collaborate with other scientists to support the development of innovative testing technologies.


Qualifications:

  • Bachelor's or Master's degree in Biochemistry, Chemistry, or a related field with a minimum of 2 years of protein characterization experience
  • Working technical expertise in analytical methodologies used to characterize protein therapeutics including SEC, IEX, HIC, CE-SDS, SDS-PAGE, etc.
  • Experience with characterization of protein-protein interactions (BLI, ELISA)
  • Experience in protein purification from bacterial protein expression system.
  • Experience handling, maintaining, and troubleshooting LC instruments (Agilent)
  • Experience with LC data analysis and interpretation.
  • Ability to work in a matrix team environment.
  • Excellent written and oral communication skills
  • Experience using electronic notebooks (Benchling)


  • Cambridge, United States Flagship Pioneering, Inc. Full time

    Company Summary Flagship Labs 97 Inc. (FL97) is a privately held, early-stage company pioneering the application of artificial intelligence to transform all science. Our Physical Sciences effort is developing a novel AI and data-driven approach to materials discovery and development to accelerate the transition to a sustainable economy. FL97 was founded by...


  • Cambridge, United States Flagship Pioneering, Inc. Full time

    Company Summary Flagship Labs 97 Inc. (FL97) is a privately held, early-stage company pioneering the application of artificial intelligence to transform all science. Our Physical Sciences effort is developing a novel AI and data-driven approach to materials discovery and development to accelerate the transition to a sustainable economy. FL97 was founded by...


  • Cambridge, United States Repertoire Immune Medicines Full time

    Job DescriptionJob DescriptionSenior Scientist, Protein Engineering and Molecular SciencesCompany Overview Repertoire Immune Medicines is a biotechnology company working to unlock and direct the remarkable power of the human immune system to treat cancer, autoimmune disease and infectious disease. The company was founded by Flagship Pioneering on the belief...


  • Cambridge, United States Repertoire Immune Medicines Full time

    Job DescriptionJob DescriptionResearch Associate II/Senior Research AssociateProtein Engineering & Molecular SciencesCompany OverviewRepertoire Immune Medicines is a biotechnology company working to unlock and direct the remarkable power of the human immune system to treat cancer, autoimmune disease and infectious disease. The company was founded by Flagship...


  • Cambridge, United States Repertoire Immune Medicines Full time

    Job DescriptionJob DescriptionResearch Associate II/Senior Research AssociateProtein Engineering & Molecular SciencesCompany OverviewRepertoire Immune Medicines is a biotechnology company working to unlock and direct the remarkable power of the human immune system to treat cancer, autoimmune disease and infectious disease. The company was founded by Flagship...


  • Cambridge, United States Broad Institute Full time

    Description & Requirements Detailed studies of cellular signaling networks related to protein phosphorylation, ubiquitylation or acetylation Unveiling the targets of drugs or identifying protein interactors through chemical proteomics technologies and affinity purification MS Developing biological understanding of response and resistance to...

  • Associate Scientist

    6 days ago


    Cambridge, United States Pioneer Data Systems Full time

    Position Details: Our client, a world-leading Pharmaceutical Company in Cambridge, MA is currently looking for a Associate Scientist to join their expanding team. Job Title: Associate Scientist (Cell Culture, Molecular Biology) Duration: 18 months contract, extendable up to 36 months Location: Cambridge, MA Note: The client has the ...


  • Cambridge, United States Repertoire Immune Medicines Full time

    Job DescriptionJob DescriptionPrincipal Scientist, Protein Production and Process DevelopmentCompany OverviewRepertoire Immune Medicines is a biotechnology company working to unlock and direct the remarkable power of the human immune system to treat cancer, autoimmune disease and infectious disease. The company was founded by Flagship Pioneering on the...


  • Cambridge, United States Fulcrum Therapeutics, Inc. Full time

    Company Overview Fulcrum Therapeutics is a clinical-stage biopharmaceutical company focused on improving the lives of patients with genetically defined rare diseases in areas of high unmet medical need. Fulcrum's two lead programs in clinical development are losmapimod, a small molecule for the treatment of facioscapulohumeral muscular dystrophy (FSHD) and...


  • Cambridge, United States Third Rock Ventures Full time

    Fulcrum Therapeutics is a clinical-stage biopharmaceutical company focused on improving the lives of patients with genetically defined rare diseases in areas of high unmet medical need. Fulcrum's two lead programs in clinical development are losmapimod, a small molecule for the treatment of facioscapulohumeral muscular dystrophy (FSHD) and pociredir, a small...


  • Cambridge, Massachusetts, United States Proclinical Staffing Full time

    Senior Research Associate, Cell & Molecular Biology - Contract - Cambridge, MAProclinical is seeking a dedicated and innovative Research Scientist for Cell and Molecular Biology. This role is a temporary contract of 6 months and is based in Cambridge, Massachusetts. Primary Responsibilities:The successful candidate will contribute to an early drug discovery...


  • Cambridge, Massachusetts, United States Eli Lilly and Company Full time

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...


  • Cambridge, United States Eli Lilly and Company Full time

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...

  • associate scientist

    6 days ago


    cambridge, United States Randstad US Full time

    associate scientist. + cambridge , massachusetts + posted 10 days ago **job details** summary + $35 - $45.39 per hour + contract + bachelor degree + category life, physical, and social science occupations + reference48076 job details job summary: As the world's largest staffing and recruitment agency in the world, we can commit to find you the...


  • Cambridge, United States Editas Medicine Full time

    Job DescriptionJob DescriptionAt Editas, we’re driven by a collective purpose, to bring transformative and life changing therapies to people living with serious diseases with the greatest unmet needs. This fuels our drive to excel in scientific innovation, allowing us to harness the power and potential of CRISPR/Cas9 and CRISPR/Cpf1 (Cas12a) gene editing....


  • Cambridge, United States Editas Medicine Full time

    Job DescriptionJob DescriptionAt Editas, we’re driven by a collective purpose, to bring transformative and life changing therapies to people living with serious diseases with the greatest unmet needs. This fuels our drive to excel in scientific innovation, allowing us to harness the power and potential of CRISPR/Cas9 and CRISPR/Cpf1 (Cas12a) gene editing....


  • Cambridge, Massachusetts, United States Moderna, Inc. Full time

    The RoleIn this role, as a Scientist, you will work with the Analytical Development and Protein Science groups. The Scientist will be responsible for developing analytical bioassays for enzymatic activity assays, with an emphasis on HPLC, LC-MS assays and/or plate-based fluorometric/colorimetric assays for enzymes with small-molecule substrates and...

  • Associate Scientist

    1 month ago


    Cambridge, United States Randstad Life Sciences US Full time

    Title: Associate ScientistLocation: Cambridge, MAContract: 5+ monthsPay: $30-34/hrJob SummaryOur group is focused on designing and developing innovative therapeutic modalities and we are looking to expand our research team of driven scientists to aid in the development of novel protein- and RNA-based therapeutics. A desire to learn new techniques and expand...

  • Associate Scientist

    2 weeks ago


    Cambridge, United States Randstad Life Sciences US Full time

    Title: Associate ScientistLocation: Cambridge, MAContract: 5+ monthsPay: $30-34/hrJob SummaryOur group is focused on designing and developing innovative therapeutic modalities and we are looking to expand our research team of driven scientists to aid in the development of novel protein- and RNA-based therapeutics. A desire to learn new techniques and expand...

  • Associate Scientist

    2 months ago


    Cambridge, United States Randstad Life Sciences US Full time

    Title: Associate ScientistLocation: Cambridge, MAContract: 5+ monthsPay: $30-34/hrJob SummaryOur group is focused on designing and developing innovative therapeutic modalities and we are looking to expand our research team of driven scientists to aid in the development of novel protein- and RNA-based therapeutics. A desire to learn new techniques and expand...