Scientist

12 hours ago


Lexington, United States The Fountain Group Full time

Details for the position are as follows:

  • 12-month contract to start with the possibility of extension or conversion depending on performance.
  • Rate: $40-43 (Master's level I) or $44.00-$52.84 (PhD level II)
  • Location: Lexington, MA

Job Description:

The Research Scientist RNAi formulations and Biophysics will be based in GNAT Research. The Research Scientist s a lab based role with hands on formulation, biophysical and analytical characterization expertise of oligonucleotides for injectable delivery.

  • Reports to Team manager/Senior Director of Nucleic acid Delivery, Formulations and Bioanalysis.
  • Interacts with peers who specialize in non-viral delivery manufacturing and characterization, Oligonuclotide chemistry and stability assays, PK and Bioanalysis of Oligonucleotides
  • As a Sci I in the Nucleic Acid Delivery, Formulations & Bioanalysis overall department, you will become a part of a multinational and diverse team consisting of Reseach Associates, Specialist/Scientists. The goal of the team is to develop preclinical formulations of conjugated oligonucleotides apply advanced analytical characterization techniques and translate these to preclinical and clinical studies through internal and external collaborations in an automated high throughput manner.
  • Identifies gaps in technological capabilities provides recommendations to guide the research agenda
  • Manage multiple external collaborations for deliverables
  • Optimize long-term storage and stability conditions of RNAi conjugates and oligonucleotide formulations in general
  • Develop robust analytical methods and assays for QC and developability assessments
  • Communicate findings internally to team via presentations and written reports
  • Ability to thrive in a multi-disciplinary and fast-paced research environment with tight deadlines

Required Skills:

  • 3 years of relevant experience with a PHD (LEVEL II) or 3+ years of relevant experience with a Masters (LEVEL I)
  • Lab experience in formulation of siRNA or oligonucleotides for systemic delivery
  • Hands on Analytical characterization of oligonucleotides
  • Experience in project management and collaborating with external CMO’s.


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