Research Laboratory Specialist Associate

2 weeks ago


Ann Arbor, United States University of Michigan Full time

Mission Statement

MDentistry: advancing health through education, service, research and discovery.

MDentistry Core Values: Compassion, Leadership, Excellence, Responsibility, Trust, Creativity, Inclusion

The mission of the University of Michigan is to serve the people of Michigan and the world through preeminence in creating, communicating, preserving and applying knowledge, art, and academic values, and in developing leaders and citizens who will challenge the present and enrich the future. The University of Michigan is committed to foster learning, creativity and productivity, and to support the vigorous exchange of ideas and information, not only in the classroom but in the workplace by: 

Creating a work environment in which people treat each other with respect and dignity, regardless of roles, responsibilities or differences.  Providing support, direction and resources enabling us to accomplish the responsibilities of our jobs and to reach the goals that are set for professional and personal growth.

Who We Are

The School of Dentistry (SoD) Periodontics & Oral Medicine department is looking for you to join one of our research laboratory teams, reporting to the Principal Investigator. We have an exciting opportunity for a Research Laboratory Specialist Associate. In this role, you will study the regulatory mechanisms controlling hematopoietic stem cell (HSCs) function during normal and pathologic hematopoiesis. We use a variety of genetically engineered mouse models combined with cell cultures to gain insight into the cellular and molecular mechanisms that control HSC identity to improve therapeutic use of HSCs and to better understand malignant transformation. Our organization supports the SoD’s mission of “Advancing health through education, service, research, and discovery.” The Periodontics & Oral Medicine department supports employee development through project opportunities, cross-unit collaboration, and the university’s extensive professional development catalog. 

Why Work at Michigan?

The School of Dentistry is consistently ranked as the #1 dental school in the United States and the world. We embrace diversity in many forms and champion diversity of thought and culture. Our Mission, core values, and additional information about our school can be found on our website. The University of Michigan also offers comprehensive benefits to help you stay well and to support you as you plan for a secure future. Benefits include:

Generous paid time off for vacations, holidays, sick time, season days, and paid parental leave. A retirement plan that provides two-for-one matching contributions after the first year of employment. Many choices for comprehensive health insurance. Life insurance. Flexible spending accounts for healthcare and dependent care expenses. Work-life programs to strengthen a workplace culture that supports personal and family life, including child care, elder care, lactation resources, and mental and emotional health services.

Responsibilities*

You will be primarily responsible for conducting research related to the molecular mechanism controlling hematopoietic stem cells and their function during blood production and bone marrow transplantation by using primary hematopoietic progenitors and in vivo models. You will be working on research projects related to hematopoietic malignancies, mainly B cell lymphoma, with the goal of enlightening novel molecular therapeutic targets.

In consultation with the PI, you will be responsible for the design and execution of experiments. Also responsible for preparing research results for basic data analysis, publication and for grant submission. You will assist the PI in the writing of grant proposals and the acquisition of support from outside agencies. You will be responsible for general laboratory care and procedures. Laboratory procedures include maintaining bacterial and eukaryotic cell cultures, and performing molecular microbiology assays, including real-time PCR. You will mentor students in DNA and RNA isolation, library preparation for sequencing, aerobic and anaerobic bacterial cultivation methods, tissue sectioning of frozen or paraffin embedded tissue, histological stains. You will maintain detailed records of all experiments and data, uploading to online lab servers and lab notebooks. Conducts analysis of data, interprets and implements research methodology, in consultation with the PI and/or senior research staff. You will be responsible for lab organization – perform laboratory maintenance activities, including preparing general lab solutions, sterilizing lab equipment, ordering supplies, maintenance and documentation of lab safety for compliance, and data collection/management. You will also be responsible for lab safety and hygiene.

Required Qualifications*

Bachelor's degree in Biology, Biochemistry & Biophysics, Cell/Cellular Biology, Genetics, Microbiology, Immunology, Biomedical Sciences, or Biomedical Engineering. 1+ years of research experience.  Experience planning, coordinating and conducting experiments in a standard laboratory setting. Experience evaluating research findings, planning the processing and analysis of research data obtained. Experience with multi-tasking, attention to details, thinking critically and being able to work independently and in a group. Experience with maintaining regular attendance to complete the responsibilities of the position.

Desired Qualifications*

Experience working with mouse models.

Work Locations

This position is located at the School of Dentistry at N University Ave.



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