Senior Scientist II
4 weeks ago
Allergan Aesthetics, an AbbVie Company is seeking a highly motivated, hands-on experimentalist for the exciting role of Senior Scientist II, Protein Science within the discovery research Toxin Innovation program in Irvine, CA . The successful candidate will be a key member of a Protein Science team, leading a small team of scientists and supporting the generation and production of novel biotherapeutics with improved efficacy, selectivity and biophysical properties for successful manufacturing. As part of a matrixed organization, he/she/they will have a critical role in developing and executing protein expression and purification strategies using discovery approaches and scale to select, optimize, and prioritize therapeutic protein candidates for advancement.
The Senior Scientist II is responsible for leading her/his/their team including supporting active bench work with respect to the recombinant expression, purification and quality characterization of early-stage discovery proteins. The successful candidate will leverage their strong technical expertise in E. coli protein expression, with practical knowledge of eukaryotic expression systems (baculovirus, mammalian). Demonstrated proficiency with AKTA FPLC systems developing, optimizing, and executing purification strategies (IMAC, IEX, SEC, HIC) to purify proteins with or without affinity tags is a requirement. The candidate is expected to possess expertise in characterizing proteins (SDS-PAGE, native PAGE, ELISA, Western Blot). Hands-on experience with HPLC separation methods (RP, SEC, IEX), dynamic light scatter (DLS) and differential scanning fluorimetry (DSF) is desired. The candidate is expected to execute experiments with substantial independence and to provide strong mentorship to his/her/their team. The candidate is expected to participate in discussions regarding the design of experiments and with guidance, have the ability to develop modified or new protocols and methods.
The position requires the individual to work with and in areas requiring select agents and toxins access (i.e. Biosafety level 2 laboratories). Access to and use of select agents is regulated by federal policies. Therefore, the candidate must conduct all work activities in compliance with AbbVie internal and applicable regulatory requirements. AbbVie internal requirements include compliance with ethics, environmental health and safety, financial, human resources, and general business policies, requirements, and objectives.
The position also requires the candidate to lead discovery projects as project lead and to productively interact with cross-functional and matrixed teams across AbbVie for progressing the project, making quick strategic decisions for timely deliverables and milestones.
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Senior Scientist I
1 month ago
Irvine, California, United States Allergan Aesthetics Full timeJob Description The Toxins Innovation team in discovery research is seeking a self-motivated, discovery-oriented, senior research scientist with a proven industry track record in leading mass spectrometry-based protein characterization projects and initiatives. This is a senior, laboratory-based role, and the successful candidate is expected to have...
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Senior Staff Scientist
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Irvine, California, United States Solugenix Corp Full timeOverview: Senior Staff Scientist Irvine, CA (Hybrid) Direct Hire Job ID 2024-9849 Solugenix is assisting a client in their search for a Senior Staff Scientist. This is a direct hire opportunity based out of Irvine, CA (Hybrid) The responsibilities of this position include, but are not limited to initiating, planning, conducting, and directing...
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Analytical Scientist
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Clinical Laboratory Scientist II
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Clinical Laboratory Scientist II
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Scientist l
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Irvine, California, United States Allergan Aesthetics Full timeJob Description The Neurotoxin Research Group at AbbVie is seeking a highly motivated and innovative candidate for the role of Scientist, Biological Research. The successful candidate for this position will contribute to projects aimed at pharmacological characterization of protein-based therapeutics. Under supervision by senior personnel, he/she will be...
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Senior Staff Scientist
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Senior Staff Scientist
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Senior Staff Scientist
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Associate Director, Biological Research
2 weeks ago
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Senior Data Scientist
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Analytical Scientist
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Analytical Scientist
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Analytical Scientist
2 days ago
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Analytical Scientist
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Scientist II, Bioassay Development
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