Scientific Director, Precision Medicine Immunology- Head of Rheumatology

1 month ago

Worcester Massachusetts, United States AbbVie Full time
Job Description

The Precision Medicine Department at Abbvie is committed to advancing drug development and patient care through building a deeper understanding of disease biology and developing tools to optimize clinical decision making and customize treatment for individual patients. Abbvie is seeking a highly motivated and experienced translational scientist to lead a team of senior scientists accountable for driving the development, planning, and execution of the clinical translational research and precision medicine strategy across the rheumatology drug pipeline at Abbvie. 

Key Responsibilities:

Build and lead an internal team of highly experienced and accomplished translational scientists (Precision Medicine Leads) accountable for defining and implementing the translational research and precision medicine strategy in for disease areas (RA, PsA, SLE, etc..) and assets being developed for rheumatology.

Responsibilities extend from Lead Optimization in Discovery through mature product life cycle in Development:

Define translational research strategy in rheumatology or gastroenterology to support clinical success of pipeline assets, including PD/TE biomarkers, POM biomarkers, patient selection/stratification strategies, and development of novel disease biomarkers.

Manage the design, conduct, interpretation and reporting of biomarker data/activities for pipeline assets in line with the development, regulatory and commercial strategies

Lead asset-specific translational projects/teams in a matrix environment. 

Coordinates appropriate scientific and medical activities with internal stakeholders (i.e. commercial, clinical operations, discovery, statistics, regulatory, etc.) to execute high quality biomarker strategies in the clinic.

Ensure, in collaboration with project leaders and asset-specific translational team members, that clinical translational sciences budgets, timelines, publication strategies and regulatory compliance requirements are factored into programs' scientific activities.

Serve as Precision Medicine Lead for one or more assets within the Immunology pipeline

Provide subject matter expertise on cross-functional teams defining broader corporate strategy in rheumatology.

Initiate new areas of investigation and implement cutting-edge technologies that are scientifically meaningful, reliable and can be incorporated directly into a clinical development program.

Develop productive collaborations with key stakeholders within Abbvie such as Discovery Immunology, CDx, Clinical Development, etc

Establish external network and build collaborations that complement internal efforts to advance mechanistic understanding of therapeutics and inform development opportunities.

Prepare and present summaries of translational data for discussions with key stake holders across multiple functional areas.

Significant Work Activities -Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day)

 

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