Postdoctoral Fellow-MSH-12909-034

Postdoctoral Fellowship

Division of Pulmonary, Critical Care and Sleep Medicine

(Icahn School of Medicine at Mount Sinai)

Key Words: Climatic Exposure Epidemiology, Environmental Medicine, Public Health, Biostatistics, Global Health and Medicine

The Division of Pulmonary, Critical Care and Sleep Medicine at the Icahn School of Medicine at Mount Sinai is seeking a Postdoctoral Fellow. The division conducts multidisciplinary clinical and translational research with state-of-the art equipment and cutting-edge technology for diseases and disorders across the lifespan. A fully funded Postdoctoral Fellow position is available with Dr. Alison Lee at the Icahn School of Medicine at Mount Sinai in NYC. Funding is guaranteed for 2 years with potential for further support. Dr. Lee's research leverages an NIH-funded ongoing pregnancy cohort study in Kintampo, Ghana (The Ghana Randomized Air Pollution and Health Study, GRAPHS) investigating the impact of perinatal exposures (both chemical and non-chemical) on maternal-child health broadly and the programming of chronic disease risk. Dr. Lee's community-engaged and solutions-oriented research focuses on understanding how exposure to air pollution, humid-heat, and precipitation/drought over pregnancy and early childhood program future health. Research studies consider a range of outcomes including growth, lung health and cardiovascular health in both mothers and children. Mechanisms examined include a specific focus on mechanisms including DNA methylation, non-coding microRNAs and long noncoding RNAs, and extracellular vesicle communications. Metabolomics and microbiome are also of interest. 

The successful postdoc will lead epidemiology and computational investigations of how these high-resolution exposures, and molecular mechanisms, are associated with human health.

Responsibilities: 

• Move forward several projects. 
• Produce two or more first authored manuscripts per year

• Assist with the supervision of research coordinators. 

• Maintain active collaborations with other labs and universities

• Apply for pilot grants to develop new research contributions

• Submit mentored-career award (K award or equivalent) by year two of postdoctoral fellowship

Examples of active projects include:

• Early life household air pollution, metal composition and cardiovascular health: Evidence from GRAPHS (R01 ES034433)

• Child lung development following a cookstove intervention: Evidence from GRAPHS (R01 ES026991)

• Building a climate cohort to monitor health impacts of climate change in Ghana (Wellcome Trust Climate Impacts Award)

Applicants should possess an M.D. or Ph.D. in Environmental and/or Molecular Epidemiology, or alternatively, in other relevant disciplines, such as Statistics/Biostatistics, Computational Biology, Machine Learning, or Bioinformatics, with relevant previous work and interest in environmental health. Strong quantitative skills, practical experience working with complex epidemiology data, and familiarity with the R statistical software packages, are also necessary. Experience with high dimensional molecular data such as Illumina BeadChip methylation (450K, 850K or EPIC) and RNA-seq data is strongly preferred. Excellent written and oral communication skills and a willingness to work as part of a collaborative team are required. 

Team: The fellow will work closely with Dr. Lee and will be part of an interdisciplinary team of environmental epidemiologists, epigeneticists, and computational biologists dedicated to environmental health investigations.

Principal Investigator: Alison Lee, MD, MS, Associate Professor of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine

SPOC-UAW Local 4100 at Icahn School of Medicine (Post Docs), 034 - Pulmonary MSH - ISM, Icahn School of Medicine