Scientist, Discovery

2 weeks ago


Rockville, Maryland, United States Arcellx Full time

Who We Are
Arcellx is a public, clinical-stage biotechnology company reimagining cell therapy by engineering innovative immunotherapies for patients with cancer and other incurable diseases. We believe that cell therapies are one of the forward pillars of medicine and our mission is to destroy cancer and advance humanity by developing cell therapies that are safer, more effective, and more broadly accessible.

Our team members are made up of talented innovators and dreamers working from our offices in Rockville, Maryland, and Redwood City, California. At Arcellx, we hire exceptional people and create a fun, diverse, supportive, and informal environment that allows everyone to do their best work.

What Matters To Us
Living our core values is essential to maintaining a work environment that is high-performing, inclusive, and collaborative. We look for candidates who demonstrate strong values alignment and bring different backgrounds, viewpoints, and abilities to the team.

Arcellx Core Values

  • Start with authenticity: We foster an inclusive environment where each person can bring their authentic self to work.
  • Think 'we' before 'me': We prioritize collective success, collaborating and supporting one another to achieve our shared goals.
  • Embrace the challenge: We deliver exceptional results by working with shared determination and a commitment to doing what's right.

How You'll Make a Difference
As a
Scientist
, your mission is to execute protein and molecular biology engineering strategies to advance projects within Arcellx's Discovery group. Engaging with a cross-functional team in a fast-paced environment, you'll identify and develop Arcellx's lead therapeutic candidates. Our potentially life-saving treatments would not exist without the work of our talented Discovery scientists; this role will have a tremendous impact on our pipeline and ability to deliver novel and effective drugs to patients.

The "Fine Print" – What You'll Do

  • Work with an interdisciplinary team of scientists to design, engineer and express recombinant proteins for use in the discovery and development of cancer therapies.
  • Design, construct and evaluate expression plasmids. Perform transfections, transductions, phage and yeast display enabled selections & screenings, binding kinetic assessments and flow cytometry as needed.
  • Develop new methods, technologies and processes when necessary for project.
  • Exercise significant technical discretion in the design, execution and interpretation of experiments.
  • Communicate progress and project recommendations to team members.

Skills And Experience We Look For

  • BS or MS in the life sciences (e.g., biology, genetics, biochemistry, chemistry, chemical engineering, bioengineering) with 4-8 years post-degree lab experience or PhD in the life sciences with 0-3 years post-degree experience.
  • Must demonstrate mastery of molecular biology methods, including primer design, PCR, gel electrophoresis, expression construct design cloning and sequence analysis.
  • Preferred skills include: methods for the characterization of recombinant protein quality and binding, protein display (phage, yeast and library preparation).
  • Preference for experience in drug development, immunology or protein engineering.
  • The ability to independently plan, organize, and prioritize work activities. The ability to work collaboratively in interdisciplinary teams.

Rewards at Arcellx
Our people are our greatest asset, and supporting their well-being is an essential part of delivering on our mission and impacting the lives of patients. Putting this belief into practice means offering strong compensation and benefits.

The base salary range for this position is $100,000 - $120,000 per year. Where a candidate falls within that range is determined by factors such as years of experience. Our compensation package also includes an annual bonus based on company goals and an equity (RSU) grant. We do offer relocation assistance for roles if required.

Our market-leading benefits package includes: 100% coverage for medical, dental and vision for team members and dependents, unlimited vacation, a 3-day weekend every month, fully-paid parental leave for up to 6 months, tuition reimbursement, 401k employer contribution and more.

Join us in our quest to reimagine cell therapy and destroy cancer. For more on our technology, culture, and team, go to

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