Research Scientist

23 hours ago

Seattle, Washington, United States Bristol Myers Squibb Full time $70,250 - $70,525 per year

Job Title: Research Scientist

Location: Seattle, WA

Duration: 12 Months

Pay Rate: $ $70.25/ hr on W2

100% onsite role

Work schedule: M - F core business hours

Top 3 to 5 skills/must haves:

  • Tissue/cell Culture
  • Gene editing
  • Flow Cytometry
  • CAR-T is a plus

In this role as a Scientist, Non-Viral Gene Editing Platforms, the ideal candidate:

  • Spends a majority of the time working in the lab independently executing experiments and recording detailed ELN entries
  • Proactively communicates and aligns with team members to achieve results and support cross-functional activities
  • Works diligently within the team to develop and optimize non-viral gene editing platform protocols and implement new technologies for continuous improvement
  • Routinely generates CAR-T cells including non-viral gene editing, expansion, and cryopreservation of engineered cells
  • Independently analyses and interprets experimental data, experience with large and complex datasets a plus(e.g., next-gen sequencing)
  • Thoroughly characterizes engineered CAR-T cells including phenotypic analysis via flow cytometry, invitro cytotoxicity assays (e.g., Incucyte), and genomic DNA extraction for downstream molecular analysis
  • Leverages their knowledge of molecular biology for in silico design of DNA sequences of large and complex engineered cargo in coordination with the molecular engineering team
  • Actively troubleshoots routine problems and initiatives related to continuous improvement or development of new approaches / technologies
  • Generates key data to support decisions that impact the larger team
  • Presents findings in multidisciplinary meetings, logically explaining complex scientific concepts and clearly highlighting key messages
  • May represent department or team on program/project team or sub-team

Basic Qualifications:

  • Bachelors Degree (5+ years of academic and / or industry experience) Or
  • Masters Degree (3+ years of academic and / or industry experience) Or
  • Ph.D. or equivalent advanced degree in the Life Sciences (No experience necessary)

Preferred Qualifications:

  • Experience culturing T cells including aseptic technique, T cell activation, and maintenance of primary cell cultures
  • Experience with multi-color flowcytometry including complex panel design and multi-parameter data analysis (FlowJo)
  • Hands-on experience with gene editing technologies (CRISPR/Cas9 preferred)
  • Strong knowledge of molecular biology and prior experience with DNA design tools such as Benchling, SnapGene, etc.
  • Experience designing and generating libraries for pooled screens and/or developing automated screening platforms
  • Ability to effectively multi-task, independently organize time, and can develop timelines and deliver results accordingly
  • Demonstrated ability to work within a team and thrive in a fast-paced and ever-changing environment
  • Detail oriented with excellent verbal and written communication skills and careful documentation (prior ELN experience a plus)

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