Associate Engineer II/ Associate Scientist – Downstream Development
1 week ago
We're Hiring: Associate Engineer II (Contract)
We are looking for an energetic and talented
Associate Engineer II (contract)
to contribute to the
Polysaccharide development and manufacturing group
. The organization is developing a multi-valent polysaccharide based conjugate vaccine,
based on a novel carrier protein produced using the Xpress CF platform. Polysaccharides are a critical component in conjugate vaccines.
The
successful candidate will have practical laboratory experience related to biotechnology,
biopharmaceuticals, or vaccine industries
.
Specifically, the candidate will have
experience with
downstream purification techniques and analytical techniques to support polysaccharide downstream development.
Location:
San Carlos, United States
Work Mode:
Work From Office
Role:
Associate Engineer II (Contract)-Polysaccharide Downstream Process Development
What You'll Do
- Assists in execution of downstream process development experiments including process characterization
studies.
- Preparing buffers and reagents.
- Operate and maintain instrumentation for polysaccharide purification including automated
Microfluidizers, TFF systems, Akta chromatography skids, automated filtration units and continuous centrifuges.
- Perform analysis and interpret results for polysaccharide and impurity assays (Anthrone, Lowry, SEC-MALS, and HPAEC-PAD).
- Keep accurate and current records of development experiments and/or project related activities in
laboratory notebooks or electronic notebook.
- Review executed protocols and batch records.
- Present/communicate data to polysaccharide team.
- Contribute to technical discussions within the polysaccharide team.
- Writes R&D protocols, batch records, and reports in support of process development.
- Works within a team environment and provides support as necessary to further the team's Initiatives.
What We're Looking For
BS in Chemical Engineering, Biochemistry, or a related discipline,
**with minimum 2 years of relevant
industry experience**
. MS without experience; or equivalent work experience.
Practical experience with and theoretical knowledge of traditional processing unit operations including
Chromatography, TFF, depth filtration, continuous centrifugation, and Microfluidization.
Familiarity with DoE (Design of Experiments) principles; practical experience with DoE software a plus.
Process characterization experience is a plus.
Demonstrated proficiency with engineering principles involved in scaling processes from lab to pilot
scale a plus.
Proficient with computer programs such as Microsoft Excel, Word, PowerPoint, Visio and JMP.
Working knowledge of the requirements of GMPs.
Demonstrated success working in a cross-functional team environment on multiple projects; ability to
work effectively as a member of a team to deliver results.
Strong interpersonal skills, with excellent written and verbal communication skills.
Ready to make an impact? Apply now and let's innovate together
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