Sr. Scientist/Engineer

2 weeks ago


San Diego, California, United States Shreenika Full time

Job Title: Sr. Scientist, Downstream Processing

Location: San Diego

Job Type: Full-Time

Work Authorization: Applicants must be authorized to work in the U.S. without employer sponsorship.

About the Role

We are seeking a Senior Downstream Processing Scientist/Engineer to join our growing team at Shreenika. The ideal candidate will lead process development, scale-up, and optimization of product recovery and purification from microbial fermentation and/or enzymatic biocatalysis processes. This individual will be responsible for designing, executing, and analyzing DSP unit operations that achieve robust yield, purity, and cost targets at laboratory, pilot scale and commercial scale. The role will collaborate closely with fermentation, analytical, and formulation teams to establish end-to-end integrated bioprocesses. We're looking for someone who is scientifically curious, hardworking, and brings a collaborative, can-do attitude to the lab every day.

At Shreenika, you'll work with a passionate and interdisciplinary team at the forefront of bioengineering. We value innovation, integrity, and initiative — and we're excited to welcome a new scientist who shares our drive to make a real impact.

Key Responsibilities

As Sr. Scientist/Engineer, your responsibilities will include, but are not limited to:

  • Lead the development and optimization of downstream processes for small molecules, peptides, and proteins derived from fermentation.
  • Translate lab-scale DSP methods into pilot and commercial production workflows; define
  • Provide technical guidance and mentorship to junior team members.
  • Collaborate cross-functionally with fermentation, analytics, and manufacturing partners to support scale-up and technology transfer.
  • Ensure timely delivery of high-quality material for customer projects and internal R&D.

Qualifications

  • Ph.D. in Chemistry, Biochemistry, or Bio/Chemical Engineering, or a related field with 5 years of relevant industry experience;

OR M.S. with 5 -7 years;

OR B.S. with 7 -10 years of relevant industry experience.

  • Strong background in purification of peptides, proteins, and small molecules from fermentation broth.
  • Demonstrated experience and success in pilot-scale and commercial DSP operations.
  • Strong hands-on laboratory and process development skills.
  • Strong understanding of mass transfer, thermodynamics, and process scale-up principles.
  • Proven technical expertise and problem-solving ability in downstream processing.
  • Prior management or team leadership experience.
  • Excellent organizational, documentation, and communication skills.
  • Positive attitude, team-oriented mindset, and strong work ethic.
  • Must be legally authorized to work in the United States without employer sponsorship.

Job Type: Full-time

Pay: $100, $140,000.00 per year

Benefits:

  • 401(k)
  • 401(k) matching
  • Dental insurance
  • Health insurance
  • Paid time off
  • Vision insurance

Work Location: In person



  • San Diego, California, United States Amazon Full time $143,300 - $247,600

    The Private Brands team is looking for a Sr. Research Scientist to join the team in building science solutions at scale. Our team applies Optimization, Machine Learning, Statistics, Causal Inference, and Econometrics/Economics to derive actionable insights about the complex economy of Amazon's retail business and develop Statistical Models and Algorithms to...


  • San Diego, California, United States Amazon Full time

    The Private Brands team is looking for a Sr. Research Scientist to join the team in building science solutions at scale. Our team applies Optimization, Machine Learning, Statistics, Causal Inference, and Econometrics/Economics to derive actionable insights about the complex economy of Amazon's retail business and develop Statistical Models and Algorithms to...


  • San Diego, California, United States ClearNote Health Full time

    Job Title: Sr. Scientist Product DevelopmentReports to:    VP, Product DevelopmentFLSA: ExemptLocation: San DiegoPosition Summary:  We are seeking a highly skilled Senior Scientist, Product Development with expertise in Molecular Diagnostics to lead the development and optimization of cutting-edge molecular assays for early cancer detection. The...


  • San Diego, California, United States Oneida Total Integrated Enterprises Full time

    :Sustainment & Restoration Services (SRS) is an 8(a) firm that provides engineering, science, construction, munitions, and specialized professional services solutions for customers nationwide.SRS has an immediate opening for a Geologist, Engineer, or Environmental Scientist - Junior to Mid Level based hybrid in one of our California offices (San Diego,...

  • Senior Scientist

    2 weeks ago


    San Diego, California, United States Pivotal Full time

    Title: Senior Scientist / Principal Scientist, Bioprocess SciencesLocation: San DiegoJob Type: Full-TimeAbout Us: A stealth-mode biotech focused on developing best-in-class delivery for in vivo gene editing.Job Summary: We are seeking a highly motivated and experienced scientific expert to join our team as a Senior Scientist or Principal Scientist of...


  • San Diego, California, United States T3W Business Solutions Full time

    T3W Business Solutions, Inc. is a Woman-Owned Small Business with Headquarters located in San Diego, CA. It is our mission to help our clients develop strategies to optimize their use of space and resources resulting in maximum benefits; we also deliver quality data and analysis to support our client's daily facility operations, planning, and compliance...


  • San Francisco, California, United States Forensic Analytical Crime Lab Full time

    Sr. Forensic Scientist (Toxicology Consultant)Organization:Forensic Analytical Crime LabType:PART-TIME | Hybrid Schedule | Occasional Travel for TestimonyTHE JOBForensic Analytical Crime Lab is seeking a skilledSr. Forensic Scientist (Toxicology Consultant)to join our team of General Criminalist experts. We are looking for an experienced forensic...


  • San Diego, California, United States Neurocrine Biosciences Full time

    Who We AreAt Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs.What We DoNeurocrine Biosciences is a leading...


  • San Diego, California, United States FICO Full time

    FICO (NYSE: FICO) is a leading global analytics software company, helping businesses in 100+ countries make better decisions. Join our world-class team today and fulfill your career potentialThe Opportunity"In this role, you will be a member of a highly talented team of engineers and scientists enabling advanced predictive models deployed into cloud-based...


  • South San Francisco, California, United States Twist Bioscience Full time $127,000 - $200,000

    Scientist / Sr Scientist / Staff Scientist (NGS Applications) in South San Francisco Job DescriptionWe are seeking a highly motivated and technically proficient Scientist to join our dynamic Next-Generation Sequencing (NGS) product development team. In this pivotal role, you will be instrumental in evaluating, optimizing, and supporting cutting-edge NGS...