Scientist, Biologics

2 weeks ago

Spring House, Pennsylvania, United States Johnson & Johnson Innovative Medicine Full time

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at

Job Function
Discovery & Pre-Clinical/Clinical Development

Job Sub Function
Biotherapeutics R&D

Job Category
Scientific/Technology

All Job Posting Locations:
Spring House, Pennsylvania, United States of America

Job Description
About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at

Johnson & Johnson Innovative Medicine R&D is recruiting for a Scientist, Biologics located in Spring House, PA.

We are seeking a Scientist, Biologics to join our innovative team within Discovery, Product Development and Supply (DPDS).

Principal Responsibilities

  • Design and execute experiments to assess high-concentration properties of lead molecules, including viscosity, concentratability, stability, aggregation, and self-association.
  • Set up and manage stability studies; prepare samples for biophysical analysis.
  • Conduct high-throughput biophysical measurements using techniques such as, NanoDSF, GXII, Chromatography (Size Exclusion (SEC), Hydrophobic Interaction (HIC), CIC), Capillary Isoelectric Focusing (cIEF), Dynamic Light Scattering (DLS), Mass photometry.
  • Execute methods of automation workflows: execute methods on Liquid Handlers for sample preparation (mixing, dilution, plate transfer, plate mapping).
  • Independently interpret and communicate experimental results to program teams and senior management.
  • Innovate and implement new techniques to assess developability and biophysical characteristics of therapeutic candidates.
  • Optimize biophysics characterization workflows to improve throughput and data quality.
  • Serve as a Biophysics representative on multidisciplinary project teams, contributing scientific insights and strategic direction.

Qualifications

  • A minimum of a Bachelor's degree in Biochemistry, Protein Analytical Chemistry, Biophysics, Chemistry, or a related discipline is required. Master degree in Biochemistry, Protein Analytical Chemistry, Biophysics, Chemistry, or a related discipline is preferred.
  • A minimum of 5 years of relevant industry experience with a Bachelor's degree or a minimum of 3 years of relevant industry experience with a Master's degree is required.
  • Solid understanding of protein science and biophysical principles is required.
  • Hands-on experience characterizing therapeutic proteins and antibodies using a broad array of biophysical and stability techniques, including SEC, DSF, HIC, GXII, and/or DLS is required.
  • Experience with high-throughput liquid handling systems is preferred.
  • Experience in maintaining written records of work in the form of laboratory notebooks (paper or electronic) is required.
  • Must have excellent verbal and written communication skills.
  • Must have strong interpersonal skills.
  • The ability to report data and present findings to management is required.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (ra-) or contact AskGS to be directed to your accommodation resource.

Required Skills
Preferred Skills:
Analytical Reasoning, Biochemistry, Chemistry, Manufacturing, and Control (CMC), Coaching, Collaborating, Conducting Experiments, Data Quality, Drug Discovery Development, Molecular Diagnostics, Patent Applications, Pharmacogenetics, Report Writing, Research Documents, Scientific Research, Technologically Savvy, Written Expression

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