Executive Director, Oncology Business Unit Strategy

4 days ago


Gaithersburg, United States AstraZeneca Full time

Introduction to role:Drive innovation and impact at AstraZeneca by leading strategy for our industry-leading oncology pipeline. Collaborate with R&D and the Oncology Business Unit to shape and deliver cutting-edge therapies that improve patient outcomes and bring us closer to eradicating cancer.As Executive Director, Oncology Business Unit (OBU) Strategy, you will lead a high-impact agenda at the intersection of science, medicine, and business. Working with a team of experts across Oncology R&D and the OBU, you will be responsible for creating and implementing strategies to deliver an industry‑leading and innovative oncology pipeline that improves patient care and outcomes. These strategies will be built through rigorous analyses, actionable insights, innovative thinking, and cross‑functional teamwork. This is an opportunity for a motivated, collaborative, data‑driven leader to help AstraZeneca advance its bold ambition to one day eradicate cancer as a cause of death.Accountabilities: Set integrated oncology strategy: Lead development and implementation of therapy area, tumour, and indication strategies that align into a single, company‑wide oncology strategy with Oncology R&D and global franchise partners.Engage senior leadership: Provide disciplined, insights‑driven valuations and strategic recommendations to C‑suite stakeholders to guide portfolio and investment decisions.Own tumor portfolio leadership: Serve as the single point of contact and “single voice” for OBU tumor strategy, chairing bimonthly tumor forums and establishing best practices and transparent coverage across priority tumors (, Breast, Lung).Drive commercial analytics and forecasting: Lead market research, forecasting, and insight generation to shape global brand strategies, R&D decisions, supply planning, and TA scenario analyses across multiple GPTs and assets.Deliver robust pipeline forecasts: Produce rigorous, assumption‑based forecasts for all tumor pipeline assets through the annual cycle, clearly articulating risks, opportunities, and context for senior leaders.Ensure process excellence and governance: Drive clarity and consistency across key business processes (forecast reviews, investment cases, TA/portfolio reviews, business and audit reviews), including partnering with Finance VPs on annual impairment assessments.Navigate complex development and market dynamics: Integrate study designs, TPPs, CDPs, combination strategies, competitive and pricing landscapes, and stage‑specific disease strategies to inform prioritization and investment.Steward major investments and opportunities: Lead large investment requests and business opportunity assessments to optimize value creation across evolving tumor markets.Lead and influence across the enterprise: Guide and develop Directors/Associate Directors, maintain trusted partnerships with clinical, commercial and strategy leaders, and influence senior stakeholders across OBU and Oncology R&D without formal authority.Essential Skills/Experience:MBA or PhD10+ years in biopharmaceuticals or related fieldsExtensive experience in oncologyStrong consultative and communication skillsA strong scientific background and strategic analytical skillsProven experience in pharmaceutical industry or consulting in which you have inputted to global pipeline strategy (market assessment, competitor analysis, forecasting)Excellent analysis and fact-based decision-makingExperience with data and/or a science research/ bio-pharmaceutical environmentHighly intellectually capable with agility and adaptabilityMotivated by working in a fast-paced field with clear societal impactUnderstanding of general business and core marketing principles and application to future healthcare market challengesFamiliar with the oncology drug development process and necessary strategic and commercial touch pointsAble to influence without authority and establish and maintain credibility with senior audiencesResourceful, motivated, decisive and proactive; must be able to manage multiple priorities in a fast-growing organization;Attention to detail but also a big picture thinker & communicatorA critical thinker with experience of identifying and driving key projects and providing researched, verified, relevant information to leaders.Preferred Skills/Experience:PhD in life sciencesExperience of setting up short- and long-term strategic plansUnderstanding of clinical data and clinical trial designExperience in at least two major geographies ( US, EU, Japan, China)Thorough understanding of regulatory and pricing dynamics in major marketsAre you ready to bring new insights and fresh thinking to the table? Brilliant We have one seat available, and we hope it’s yours. Apply today.



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