Senior Data Scientist, Translational Medicine

15 hours ago

Waltham, United States Visterra Full time
Job DescriptionJob DescriptionSalary:

Summary

Visterra is seeking a highly motivated and skilled Data Scientist or Senior Data Scientist (commensurate with experience) to join our Translational team. This individual will play a critical role in exploratory translational data analysis, visualization, interpretation, and documentation, supporting our clinical programs. The successful candidate will work closely with cross-functional teams, including Translational & Clinical Development, Nonclinical, Research, and Bioanalytical, to drive biomarker strategy and ensure the integration of biomarker data into the drug development process. This position reports to the Principal Scientist, Translational Biomarkers, and the positions activities would span all clinical and late-stage preclinical programs. This is a full-time position located at Visterras facility in Waltham, MA.

Responsibilities

  • Conduct comprehensive data analyses using statistical methods and data visualization tools (e.g., R, Python). This includes interpreting complex datasets from clinical trials and biomarker studies to support drug development strategies. Specific responsibilities may include:
    • Format and utilize diverse data types such as clinical data (SDTM and ADaM), biomarker data, and PK/PD parameters for integrated quantitative analysis.
    • Check data quality and consistency, including iteratively checking for consistency at critical analytical nodes.
    • Generate visuals and/or tables of descriptive measures of the data (e.g., means, ranges, variances, distributions, etc.).
    • Perform specific subset analyses for correlations (e.g., relational analyses between PK/PD, safety outputs, or clinical markers).
    • Generate and clearly present graphs and other visualizations. Provide insight into the interpretation of the results. This may include how these results factor into the disease biology or mechanism of action of the therapeutic.
    • Adapt analyses to address subsequent hypotheses generated from initial outputs with the knowledge and insight to curtail tangential analyses that may not yield significant impact or relevance to the understanding of the therapeutic or disease state.
  • Develop accurate and high-quality visualizations and presentations that communicate findings clearly to various stakeholders, including non-technical audiences, within and outside the organization.
  • Contribute to the execution of biomarker strategies, integrating data from preclinical and clinical studies. Perform relational analyses of biomarkers for pharmacodynamic responses and clinical outcomes.
  • Collaborate with cross-functional teams to analyze and evaluate results, ensuring high-quality data generation and interpretation in a timely manner.
  • Author internal reports of biomarker data outputs. Support the clinical trial process by ensuring accurate documentation and reporting of data.
  • Engage in the writing and reviewing of documents, including but not limited to: clinical study reports, regulatory documents, and scientific publications or other materials (e.g., conference abstracts).
  • Performs other duties as required.

Requirements

  • Bachelors degree in the life sciences or data science, with advanced training such as a Masters or Ph.D. in biological or data sciences. Experience in data analysis, visualization, interpretation and hypothesis generation is required; this is not solely a statistical/data analysis position.
  • Prior analytical experience with clinical trial data is strongly preferred.
  • Demonstrated proficiency with data analysis and visualization tools (e.g., R). Thorough understanding of biostatistical concepts.
  • Familiarity with proteomics, genomics, or other omics data is advantageous, including an ability to converse and collaborate with in-house bioinformaticians.
  • Ability to synthesize and interpret multidisciplinary data sets, think critically, and explain distilled principles to a wide audience.
  • Familiarity with relevant good data management practices including annotation, storage, and sharing.
  • Background or knowledge in immunology or nephrology is desirable.
  • Strong verbal and written skills, with the ability to communicate effectively across a variety of audiences and generate technical reports.
  • Collaborative, goal-driven, organized, and communicative; thrives in a fast-paced environment with multiple parallel programs.

Company

Visterra is a clinical stage biotechnology company committed to developing innovative biologic therapies for the treatment of kidney diseases, with an immuno-nephrology focus. Our proprietary technology platform enables the design and engineering of precision antibody or protein-based drug candidates to modulate key disease targets. We are developing a robust pipeline of novel therapies for patients with unmet needs.

Visterra is a wholly owned subsidiary of Otsuka America, Inc., which is a U.S. holding company subsidiary of Otsuka Pharmaceutical Co., Ltd. of Japan. Visterra has approximately 125 employees, and is located in Waltham, Massachusetts.

  • Senior Data Scientist, Translational Medicine

    3 weeks ago

    Waltham, United States ZipRecruiter Full time

    Job DescriptionJob DescriptionSalary: Summary Visterra is seeking a highly motivated and skilled Data Scientist or Senior Data Scientist (commensurate with experience) to join our Translational team. This individual will play a critical role in exploratory translational data analysis, visualization, interpretation, and documentation, supporting our...

  • Senior Data Scientist, Translational Medicine

    4 hours ago

    Waltham, United States BioSpace, Inc. Full time

    Job Details Summary Visterra is seeking a highly motivated and skilled Data Scientist or Senior Data Scientist (commensurate with experience) to join our Translational team. This individual will play a critical role in exploratory translational data analysis, visualization, interpretation, and documentation, supporting our clinical programs. The successful...

  • Senior Data Scientist, Translational Medicine

    5 hours ago

    Waltham, United States Vistera Inc. Full time

    Summary Visterra is seeking a highly motivated and skilled Data Scientist or Senior Data Scientist (commensurate with experience) to join our Translational team. This individual will play a critical role in exploratory translational data analysis, visualization, interpretation, and documentation, supporting our clinical programs. The successful candidate...

  • Senior Data Scientist, Translational Medicine

    6 days ago

    Waltham, United States ZipRecruiter Full time

    Job DescriptionJob DescriptionSalary: Summary Visterra is seeking a highly motivated and skilled Data Scientist or Senior Data Scientist (commensurate with experience) to join our Translational team. This individual will play a critical role in exploratory translational data analysis, visualization, interpretation, and documentation, supporting our...

  • Data Scientist in Translational Medicine

    3 weeks ago

    Waltham, Massachusetts, United States ZipRecruiter Full time

    About the RoleWe are seeking a highly skilled Data Scientist to join our Translational team. This individual will play a critical role in exploratory translational data analysis, visualization, interpretation, and documentation, supporting our clinical programs.Key ResponsibilitiesConduct comprehensive data analyses using statistical methods and data...

  • Data Scientist Translational Medicine Innovation Leader

    1 month ago

    Waltham, Massachusetts, United States Visterra Full time

    Job OverviewVisterra is a pioneering clinical stage biotechnology company dedicated to developing innovative biologic therapies for the treatment of kidney diseases, with a focus on immuno-nephrology.Compensation PackageWe offer a highly competitive compensation package, including an estimated $140,000 - $180,000 per year, commensurate with experience. This...

  • Translational Medicine Specialist

    3 weeks ago

    Waltham, Massachusetts, United States Apellis Pharmaceuticals Full time

    Job Summary:We are seeking a highly motivated Translational Medicine Specialist to join our team at Apellis Pharmaceuticals. This role will be responsible for developing cross-functional program-level strategies to identify novel fluid, digital, imaging, and/or technology-related endpoints for use in preclinical and early-stage clinical neurology...

  • Translational Research Immunology Expert

    1 week ago

    Waltham, Massachusetts, United States AbbVie Full time

    Job SummaryWe are seeking a highly motivated and creative Principal Scientist to join our Precision Medicine Translational Research Immunology Group at AbbVie. The successful candidate will provide leadership in clinical biomarker strategy and assay development in inflammatory/autoimmune disease areas.Key Responsibilities:Lead cross-functional teams to...

  • Senior Translational Research Expert

    1 week ago

    Waltham, Massachusetts, United States Apellis Full time

    OverviewApellis Pharmaceuticals is a global biopharmaceutical company developing life-changing therapies for challenging diseases. This role offers an exciting opportunity to join our team and contribute to the development of innovative treatments.Job SummaryWe are seeking a highly skilled Senior Translational Research Scientist to lead our CNS Neurology...

  • Precision Medicine Scientist Lead

    1 week ago

    Waltham, Massachusetts, United States AbbVie Full time

    Job DescriptionWe are seeking a highly skilled and experienced Principal Scientist to join our team at AbbVie. As a key member of our Precision Medicine Translational Research Immunology Group, you will play a critical role in developing and executing our translational research strategies.Responsibilities:Design and implement clinical biomarker strategies to...

  • Senior Bioinformatics Scientist

    1 month ago

    Waltham, United States Data4Cure, Inc. Full time

    Data4Cure - Senior scientist (Leadership track) - Computational systems biology and machine learningData4Cure helps transform vast biomedical datasets and literature into knowledge to advance precision medicine. We are working at the intersection of bioinformatics, machine learning and semantic knowledge integration. Over the last few years we have developed...

  • Senior Bioinformatics Scientist

    1 month ago

    Waltham, United States Data4Cure, Inc. Full time

    Data4Cure - Senior scientist (Leadership track) - Computational systems biology and machine learningData4Cure helps transform vast biomedical datasets and literature into knowledge to advance precision medicine. We are working at the intersection of bioinformatics, machine learning and semantic knowledge integration. Over the last few years we have developed...

  • Data4Cure, Inc. | Senior Bioinformatics Scientist | waltham, ma

    1 month ago

    waltham, United States Data4Cure, Inc. Full time

    Data4Cure - Senior scientist (Leadership track) - Computational systems biology and machine learningData4Cure helps transform vast biomedical datasets and literature into knowledge to advance precision medicine. We are working at the intersection of bioinformatics, machine learning and semantic knowledge integration. Over the last few years we have developed...

  • Data4Cure, Inc. | Senior Bioinformatics Scientist | waltham, ma

    1 month ago

    waltham, United States Data4Cure, Inc. Full time

    Data4Cure - Senior scientist (Leadership track) - Computational systems biology and machine learningData4Cure helps transform vast biomedical datasets and literature into knowledge to advance precision medicine. We are working at the intersection of bioinformatics, machine learning and semantic knowledge integration. Over the last few years we have developed...

  • Translational Data Analyst for Biotech Company

    2 weeks ago

    Waltham, Massachusetts, United States ZipRecruiter Full time

    About the OpportunityWe are seeking a Translational Data Analyst to join our team. This individual will be responsible for analyzing and interpreting complex datasets from clinical trials and biomarker studies to support drug development strategies.ResponsibilitiesConduct comprehensive data analyses using statistical methods and data visualization tools...

  • Senior Scientist

    4 weeks ago

    Waltham, MA, United States National Black MBA Association Full time

    Senior Scientist (Hematology Oncology) Introduction to role: We are seeking a highly motivated Senior Scientist in cancer pharmacology with a track record of scientific excellence to join our team in Waltham, MA. As a Senior Scientist, you will be leading from the bench and a member of the in vivo team focused on delivering in vivo pharmacology datasets...

  • CNS Translational Development Specialist

    1 week ago

    Waltham, Massachusetts, United States Apellis Full time

    Job SummaryThis role offers a competitive salary range of $150,000-$190,000 per year. As a Sr. Research Scientist at Apellis, you will play a crucial part in driving innovation and developing life-changing therapies for patients with challenging diseases.About ApellisApellis is a pioneering biopharmaceutical company dedicated to harnessing the power of...

  • Senior Molecular Scientist for Cell and Gene Therapy Development

    1 month ago

    Waltham, Massachusetts, United States ElevateBio Full time

    About the RoleElevateBio is a pioneering technology-driven cell and gene therapy company, accelerating access to cutting-edge technologies and expertise to transform the future of medicine. Our integrated technologies model offers turnkey scale and biotechnological capabilities to power genetic medicines processes, programs, and companies to their full...

  • Director, Data Science

    11 hours ago

    Waltham, United States AstraZeneca Full time

    At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person. We harness digital,...

  • Immunology Biomarker Strategist

    3 weeks ago

    Waltham, Massachusetts, United States AbbVie Full time

    About This RoleWe are seeking an accomplished Principal Scientist to lead our efforts in translational medicine, focusing on rheumatological diseases such as RA, SLE, and SSc. If you have a passion for immunology and experience in developing clinical biomarkers, this could be the perfect opportunity for you.Key Responsibilities:Develop and execute clinical...