Computational Biologist

4 weeks ago

South San Francisco, United States Amgen Full time
Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Computational Biologist

What You Will Do

Let’s do this. Let’s change the world. The Computational Biology group in the Center for Technology and Innovation (CfTI) within the Precision Medicine organization at Amgen is seeking a highly motivated Computational Biologist with expertise in analyzing clinical biomarker data, including but not limited to genomics, transcriptomics, proteomics, spatial-omics, flow cytometry, immunoassays, and other biomarker assays. In this vital role you will contribute to advancing Amgen’s clinical programs and studies by integrating computational biology and bioinformatics techniques with biological and clinical data. The ideal candidate will have experience in matrixed environments, supporting therapeutic development by providing insights derived from clinical biomarker data. A background in inflammation and immunology, rare diseases, or cardiometabolic disease is preferred to support key areas of Amgen's therapeutic focus.

  • Support Amgen program/portfolio teams as a biomarker analysis lead.
  • Development of biomarker analysis plans to support precision medicine, evidence generation and reverse translation during clinical development of therapeutic molecules.
  • Design and execute workflows for biomarker data analysis, integrating genomics, transcriptomics, proteomics, imaging and biomarker measure using other assays/platforms to support Amgen's early and late clinical development programs.
  • Lead the analysis and interpretation of clinical biomarker data from various assay platforms, including imaging, flow cytometry, immunoassays, transcriptomics, proteomics, and spatial-omics, etc.
  • Design and implement computational algorithms to analyze multi-omics, multi-modal, and high-content data, with applications in target engagement evaluation, patient stratification, response prediction, indication selection, assay development, and diagnostic development.
  • Work closely with clinical scientists and biomarker leads, to extract biological insights from high-dimensional datasets and integrate them into reverse translational research and clinical development plans.
  • Collaborate cross-functionally with early development teams, biostatistics, clinical pharmacology, clinical biomarker leads, and research teams to manage data integration, analysis, and presentation.

What We Expect Of You

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications.

Basic Qualifications

  • Doctorate degree and 2 years of scientific experience

Or

  • Master’s degree and 5 years of scientific experience

Or

  • Bachelor’s degree and 7 years of scientific experience

Preferred Qualifications

  • PhD in Bioinformatics, Mathematics, Computer Science, Computational Biology or Data Science, with a minor or robust background in Biology
  • Hands-on experience in statistical modeling, machine learning, and AI applied to clinical biomarker and clinical efficacy data.
  • A strong understanding and practical skills in statistics and their use in data analysis for clinical settings
  • Proven expertise in analyzing multi-modal, multi-dimensional, and large-scale biological data.
  • Prior experience working in a matrixed biotechnology or pharmaceutical setting.
  • Proficiency in R and Python programming, with familiarity in various principles for data manipulation and visualization.
  • Strong understanding of platforms used in clinical biomarker research, including flow cytometry, immunoassays, next-generation sequencing (NGS), and proteomics.
  • Knowledge of immunology, autoimmune diseases, cardiometabolic disease or oncology, and how computational biology can drive drug discovery and development in these areas.
  • Ability to translate biological and medical questions into analytical models providing actionable results
  • Excellent written and oral communication skills with the ability to present complex data analyses in diverse settings, including cross-functional team meetings, external collaborations, and scientific publications.
  • Strong project management skills and organizational awareness, self-motivation, independence, and leadership

What You Can Expect Of Us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In Addition To The Base Salary, Amgen Offers a Total Rewards Plan, Based On Eligibility, Comprising Of Health And Welfare Plans For Staff And Eligible Dependents, Financial Plans With Opportunities To Save Towards Retirement Or Other Goals, Work/life Balance, And Career Development Opportunities That May Include

  • A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans
  • Flexible work models, including remote and hybrid work arrangements, where possible

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

  • Computational Biologist Specialist

    3 weeks ago

    San Francisco, California, United States ZipRecruiter Full time

    About the Role: We are looking for a highly motivated and experienced Computational Biologist Specialist to develop innovative computational tools and data-driven approaches that solve complex biological challenges. You will collaborate with biologists, geneticists, and data scientists to analyze genomic data, build computational models, and develop...

  • Computational Biologist

    4 weeks ago

    San Francisco, California, United States Unreal Gigs Full time

    Job Summary: Unreal Gigs is looking for a skilled Computational Biologist to join our team. The ideal candidate will have expertise in developing algorithms and computational models for sequence analysis, gene expression profiling, and protein structure prediction. Expected Salary: $140,000 - $170,000.Responsibilities:- Develop algorithms that process and...

  • Computational Biologist Specialist

    3 weeks ago

    San Francisco, California, United States Unreal Gigs Full time

    The role of a Computational Biologist Specialist at Unreal Gigs involves working with biologists, geneticists, and data scientists to develop innovative computational tools and data-driven approaches that solve complex biological challenges. If you have a passion for turning complex biological data into meaningful insights, we encourage you to apply for this...

  • Computational Biologist

    3 weeks ago

    San Francisco, California, United States University of California , San Francisco Full time

    About the OpportunityWe are seeking a highly skilled and motivated Computational Biologist to join our team at the University of California, San Francisco. The ideal candidate will have a strong background in bioinformatics and computational biology, with experience in developing and implementing novel algorithms for large-scale data analysis.The successful...

  • Computational Biologist

    2 weeks ago

    San Francisco, California, United States Genentech Full time

    As a Computational Biologist in the Proteomic and Genomic Technologies (PGT) Department at Genentech, you will play a vital role in advancing the development of large-scale data pipelines and novel bioinformatic algorithms for mass-spectrometry-based proteomic analysis. With a focus on collaborative research and innovation, this position offers the...

  • Computational Biologist Expert

    10 hours ago

    San Francisco, California, United States University of California , San Francisco Full time

    About the PositionThe University of California, San Francisco seeks a highly skilled computational biologist to join our esteemed research community at the Benioff Center for Microbiome Medicine.Candidates are expected to hold a PhD and/or MD and demonstrate exceptional research accomplishment and potential. A record of mentorship, particularly with trainees...

  • Senior Computational Biologist

    2 weeks ago

    San Francisco, California, United States Unreal Gigs Full time

    Unreal GigsWe are seeking a highly skilled Senior Computational Biologist to join our team at Unreal Gigs. This role offers an exciting opportunity to utilize your expertise in computational biology and bioinformatics to drive data-driven discoveries in the life sciences industry.About the RoleAs a Senior Computational Biologist, you will be responsible for...

  • Computational Biologist

    4 days ago

    San Diego, California, United States AA2IT Full time

    At AA2IT, we're seeking an experienced Computational Biologist to join our team in San Diego. As a key member of our immunology analytics team, you'll be working closely with multi-disciplinary teams to uncover the key biological functions and disease mechanisms driving immune-mediated diseases.We're looking for someone with extensive experience in...

  • Computational Cancer Biologist

    1 week ago

    San Francisco, United States Shennon Biotechnologies Full time

    We are a well-funded biotech startup that has developed a proprietary single cell platform that resolves a bottleneck for immunotherapy. We are currently looking for a computational cancer biologist in the field of immuno-oncology to join our interdisciplinary team. The candidate is expected to adapt quickly and communicate well, especially in a fast-paced...

  • Senior Computational Biologist for Drug Discovery

    4 weeks ago

    South San Francisco, California, United States Talent Software Services Full time

    Overview">Talent Software Services is a leading provider of contract staffing solutions in the San Francisco Bay Area. We offer a range of services, including contract, contract-to-hire, and permanent placement opportunities.">Salary and Benefits">The salary for this position is estimated to be around $140,000 - $160,000 per year, depending on experience....

  • Structural Biologist Leader

    2 days ago

    South San Francisco, California, United States Lyterian Full time

    About the RoleThis is an exciting opportunity for an experienced Structural Biologist Leader to join our team at Lyterian Therapeutics. As a key member of our Scientific Leadership Team, you will be responsible for leading our structural biology efforts to develop medicines for patients in need.Key AccountabilitiesDevelop and execute a strategy for the...

  • Senior Computational Biologist

    2 days ago

    San Diego, California, United States Spectraforce Technologies Full time

    Spectraforce Technologies is seeking a highly skilled Senior Computational Biologist to join our Companion Diagnostics team in San Diego. As a key member of our team, you will utilize your expertise in computational biology to drive precision medicine and drug development by dissecting the molecular mechanisms underlying immune-mediated diseases.We are...

  • Computational Biologist Expert

    4 days ago

    San Diego, California, United States Web-atrio Full time

    About the RoleAt Web-atrio, we're looking for a highly skilled Computational Biologist to join our Predictive Sciences team. As a key member of our team, you'll play a crucial role in analyzing multi-dimensional compound profiling data from proteomics, transcriptomics, and phenomics screens to characterize compounds' mechanism-of-action (MoA).Main...

  • Computational Biologist Specialist

    4 days ago

    San Diego, California, United States LanceSoft Full time

    **About LanceSoft**LanceSoft is a pioneer in immunology analytics, dedicated to advancing our understanding of immune-mediated diseases. We are seeking a skilled Computational Biologist to join our team and contribute to the development of innovative solutions.**Role Summary**We are looking for an experienced bioinformatician with expertise in computational...

  • Computational Biologist

    4 weeks ago

    San Francisco Bay Area, United States Amber Bio Full time

    Amber Bio is a biotechnology company pioneering new gene editing modalities using multi-kilobase edits to reach previously undruggable patient populations. Founded by pioneers in the CRISPR field from leading institutions for gene editing research, the company is developing a first-of-its-kind RNA writing platform that can correct thousands of bases at once,...

  • Senior Computational Biologist

    3 weeks ago

    San Diego, California, United States BioLegend, Inc. Full time

    BioLegend, Inc. is a leading biotechnology company that specializes in the development of innovative solutions for the life sciences industry. We are currently seeking an experienced Artificial Intelligence Machine Learning Engineer to join our team.The successful candidate will have a strong background in artificial intelligence and machine learning, with a...

  • Senior Computational Biologist for Diagnostic Assay Development

    16 hours ago

    San Diego, California, United States Exact Sciences Full time

    About the RoleWe are seeking a highly skilled and experienced Senior Computational Biologist to join our team at Exact Sciences. As a key member of our research and development group, you will play a critical role in developing innovative diagnostic assays using cutting-edge bioinformatics and computational biology techniques.

  • Senior Molecular Biologist

    3 weeks ago

    San Francisco, California, United States University of California , San Francisco Full time

    The University of California, San Francisco is seeking a highly motivated and skilled Senior Molecular Biologist to join our Hsiung Lab. This is an exciting opportunity for a researcher to contribute to innovative projects in CRISPR synthetic biology, gene regulation, functional genomics, and tissue biology.About the RoleAs a Senior Molecular Biologist, you...

  • Data-Driven Biologist

    3 weeks ago

    San Francisco, California, United States Unreal Gigs Full time

    Unlock the Secrets of Genomics and Personalized MedicineWe are seeking a skilled Bioinformatics Specialist to join our team at Unreal Gigs. As a key member of our bioinformatics department, you will play a vital role in analyzing complex biological data, developing innovative computational tools, and collaborating with cross-disciplinary teams to drive...

  • Computational Biologist

    3 weeks ago

    San Francisco, California, United States University of California , San Francisco Full time

    Job Summary">We are seeking a highly skilled Bioinformatics Programmer to join our team at the University of California, San Francisco (UCSF). The successful candidate will have a strong background in bioinformatics, molecular biology, or computer science, and excellent programming skills in Python and R.">Key Responsibilities">Carrying out data analysis on...