Senior Project Scientist

Join Our Team at Charles River

For over 75 years, Charles River has been at the forefront of supporting the discovery, development, and safe production of innovative drug therapies. As a member of our team, you will contribute significantly to the health and well-being of individuals worldwide. Your expertise, whether in life sciences, finance, IT, sales, or another field, will be invaluable to our mission. In return, we are committed to helping you cultivate a fulfilling career.

Position Overview

We are currently looking for a Senior Project Scientist specializing in Bioanalysis LCMS to join our esteemed Bioanalytical Chemistry Team.

The Bioanalytical Chemistry division plays a crucial role in evaluating test compounds through quantitative analysis of drugs in biological fluids and tissues. This encompasses both regulated and non-regulated studies, including preclinical safety assessments, pharmacokinetic/pharmacodynamic studies, and clinical trials. Team members are involved in the development and validation of quantitative LC/MS/MS methodologies, sample analysis, and the interpretation and reporting of data using validated systems. Responsibilities also include developing sample extraction techniques, optimizing LC separations, and utilizing laboratory robotics to expedite the delivery of bioanalytical results. Team members must be well-versed in GxP regulations and applicable SOPs, ensuring adherence to study protocols for accurate documentation of methods, procedures, and results.

Key Responsibilities:

• Manage a portfolio of sample analysis projects, ensuring timely completion with minimal oversight.
• Review and approve data, making final scientific and technical decisions independently.
• Understand compliance expectations and address quality assurance audit observations.
• Assist in laboratory investigations, assay troubleshooting, and quality observations.
• Serve as a Principal Investigator or Study Director, ensuring scientific integrity in studies.
• Communicate effectively with peers, supervisors, and clients to maintain project timelines.
• Document all procedures and results in compliance with regulatory standards.
• Participate in internal process improvements and harmonization efforts.

Qualifications:

• Bachelor's degree (BA/BS) with 7-9 years of relevant experience; Master's degree (MS) with 3-4 years; or Doctorate degree (PhD) with 1-2 years of relevant experience.
• Experience with LC/MS/MS is essential.
• Strong verbal and written communication skills are required.
• Familiarity with Microsoft Office Suite and the ability to learn validated systems.
• Willingness to work extended hours, including evenings and weekends, as needed.
• Ability to work under time constraints effectively.

The compensation for this role ranges from $95,000 to $105,000 annually, depending on experience, skills, education, and other relevant factors.

About Charles River

Charles River is a leading early-stage contract research organization (CRO) dedicated to supporting our partners in expediting their preclinical drug development. Our team provides exceptional safety assessment services, advanced facilities, and expert regulatory guidance. With over 20,000 employees across 110 facilities in more than 20 countries, we are well-equipped to address our clients' unique challenges. Our commitment to improving the quality of life through our work drives us every day.