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Process Development Associate Scientist

2 months ago

Philadelphia, Pennsylvania, United States InsideHigherEd Full time
Job Title: Process Development Associate Scientist

We are seeking a highly skilled Process Development Associate Scientist to join our team in the Gene Therapy Program at the University of Pennsylvania. As a key member of our Vector Core, you will be responsible for leading process development projects for upstream and/or downstream manufacturing of viral vectors.

About the Role:

As a Process Development Associate Scientist, you will be a subject matter expert in upstream or downstream manufacturing. You will independently lead lab studies to develop upstream or downstream manufacturing processes, identifying and defining critical process parameters and critical attribute parameters. You will work to design and scale-out vector processes, support process characterization, and draft documentation for regulatory purposes. Additionally, you will lead process optimization studies as needed, develop and update process protocols/SOPs, and direct the technology transfer of new or updated processes to the manufacturing group.

Responsibilities:
  • Lead process development projects for upstream and/or downstream manufacturing of viral vectors
  • Independently lead lab studies to develop upstream or downstream manufacturing processes
  • Identify and define critical process parameters and critical attribute parameters
  • Design and scale-out vector processes
  • Support process characterization and draft documentation for regulatory purposes
  • Lead process optimization studies as needed
  • Develop and update process protocols/SOPs
  • Direct the technology transfer of new or updated processes to the manufacturing group
Requirements:
  • MS Degree in Biochemical/Chemical Engineering, Biochemistry, Biology, or related disciplines + 5 to 7 years of relevant experience
  • Must have experience in mammalian cell culture, tangential flow filtration, and/or column chromatography
  • Experience in biologics manufacturing preferred
  • Knowledge of process development concepts for biological manufacturing; basic principles of various engineering disciplines required
  • Ability to operate in a fast-paced, multi-disciplinary environment
  • Must be an independent thinker, meticulous, detail-oriented, and analytical
  • Must be highly motivated, have excellent organizational, communication, and interpersonal skills
  • Must be able to work independently and as part of a multi-disciplinary team
What We Offer:
  • A competitive salary and benefits package
  • Opportunities for professional growth and development
  • A dynamic and collaborative work environment
  • Access to state-of-the-art facilities and equipment
  • A comprehensive benefits package, including health, life, and flexible spending accounts
  • Tuition assistance and retirement plans
  • Time away from work for relaxation, vacations, and personal activities
  • Long-term care insurance and wellness programs
How to Apply:

To apply, please visit our website and submit your application, including your resume and cover letter. We look forward to hearing from you