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Research Scientist

2 months ago

California, United States BioPhase Full time

Position Overview: Scientist I/II

This is a permanent role offering comprehensive benefits.

The successful applicant will be a meticulous, innovative collaborator with a background in various analytical methodologies, including high-throughput biomarker analysis and experience with multiple biological fluids such as blood, urine, and saliva. A robust grasp of immunochemistry, protein biochemistry, nucleic acid detection, and structure-property relationships is essential, along with proven practical experience with extracellular vesicles, proteins, nucleic acids, and other biochemical entities. Familiarity with assays centered on extracellular vesicles/exosomes is highly advantageous. Exceptional cross-functional communication skills, a results-driven mindset, and a strong commitment to achieving project objectives and timelines are crucial.

Key Responsibilities:

  • Conduct essential experiments to aid in the creation and refinement of innovative assays on the company’s platform.
  • Independently design, implement, and analyze research experiments utilizing immunochemistry, fluorescence/luminescence detection systems, western blotting, and additional techniques.
  • Develop inventive and practical solutions to a variety of interdisciplinary technical challenges.
  • Apply analytical and statistical methods to interpret experimental outcomes.
  • Proactively address workflow and experimental issues, taking responsibility for results, interpretations, strategies, and tactics at the project level.
  • Systematically enhance methods to optimize sensitivity and reproducibility.
  • Maintain accurate and comprehensive records of research findings electronically, adhering to quality system requirements; organize experiments and results into databases.
  • Identify and explore novel scientific and technological processes that enhance productivity and outcomes, contributing to the generation of intellectual property.
  • Communicate findings and prepare research summaries effectively.
  • Ensure laboratory practices comply with safety regulations and best practices.
  • Provide mentorship and training for junior team members.
  • Offer insights and strategies for achieving both short- and long-term project objectives.
  • Work autonomously while contributing to team goals and influencing project outcomes. Collaborate effectively, demonstrating openness and adaptability, and encouraging the same in colleagues.
  • Exhibit team influence and scientific/technical expertise in areas of specialization.
  • Set an example as a constructive team member, exercising independent judgment in developing and innovating methods, techniques, and evaluation criteria for achieving results.
  • Provide leadership, guidance, and mentoring for tasks/projects, ensuring fairness and respect for all team members.
  • Adhere to all company policies as outlined in the Employee Handbook, as well as quality procedures and regulatory standards.
  • Consistently demonstrate respect, fostering trust through openness, collaboration, and support for team members.
  • Operate with humility, integrity, honesty, and transparency.
  • Promote inclusivity, ongoing communication, and a positive attitude with both internal and external team members and stakeholders.
  • May require occasional travel.
  • Handle confidential company information with discretion.

Qualifications and Skills:

  • A Master's degree in a scientific discipline is typically required; a PhD in a related field or an equivalent combination of education and experience is preferred.
  • A PhD in Bioengineering, Chemical Engineering, or a similar field, along with 2+ years of industry experience, is preferred.
  • Experience in the development of blood-based assays is advantageous.
  • Expertise in the design and development of biochemical and/or immunoassays is preferred.
  • Self-driven with excellent organizational and observational skills.
  • Strong foundational knowledge of protein biochemistry, including antibody principles and pairing.
  • Extensive experience in various protein purification, detection, and identification techniques (e.g., Western Blots, microscopy, chromatography, centrifugation, enzyme assays, Bioanalyzer, NTA). Experience in cancer biology and/or exosomes is desirable.
  • Ability to learn and execute complex, multi-step procedures involving newly developed (RUO) software and systems.
  • Proficiency in applying statistical analysis and software (e.g., JMP, Prism, ImageJ) to inform decision-making.
  • Ability to convey research findings clearly and concisely in a collaborative environment.
  • Motivated to work in a dynamic, team-oriented, hands-on setting.
  • Strong planning, organizational, and prioritization abilities.
  • Demonstrated urgency and ownership regarding project deliverables.
  • High level of professionalism and integrity.
  • Exhibits scientific/technical capabilities with experience in implementing innovative solutions.
  • Regularly collaborates with others and provides independent insights in shaping design and research strategies. Tackles complex problems requiring in-depth analysis of situations or data.
  • Exercises judgment within broadly defined practices in selecting methods, techniques, and criteria for achieving results. Collaborates across functions and may lead a team or project. Demonstrates critical thinking abilities.
  • Must possess the necessary skills and knowledge for job responsibilities and be committed to ongoing learning and development in the field.
  • Must be adaptable and comfortable with rapidly changing priorities and responsibilities.
  • Skilled in managing a substantial workload and achieving successful outcomes, while taking on additional responsibilities and managing priorities as needed.
  • Proactive and effective in deriving solutions and utilizing data to achieve results.
  • Strong verbal and written communication skills, capable of producing accurate, timely reports/information and sharing information thoroughly with others. Must be proficient in reading, writing, and speaking effectively.
  • Exceptional listening skills with the ability to seek constructive feedback, build relationships, promote teamwork, and maintain flexibility, humility, and open-mindedness.
  • Capable of following realistic plans, setting goals, managing resources, and coordinating with others.
  • Able to work thoughtfully under pressure and within required timelines.
  • Must be comfortable and capable of performing the job within the physical requirements and conditions necessary for the role.