Process Development Senior Scientist

2 weeks ago


Thousand Oaks, California, United States Amgen Full time
About the Role

Amgen is seeking a talented Process Development Senior Scientist to join our Drug Substance Technologies - Synthetics (DSTS) group. As a key member of our team, you will be responsible for inventing synthetic routes and developing safe, robust, and cost-effective processes to manufacture synthetic and hybrid drug substances.

Key Responsibilities
  • Invent synthetic routes and develop processes to manufacture synthetic and hybrid drug substances
  • Advance enabling technologies to accelerate pharmaceutical development and improve sustainability and process efficiency
  • Support cGMP manufacturing and technology transfer to internal manufacturing facilities and external contract manufacturers
  • Ensure process performance through process understanding, modeling, and characterization
  • Contribute to drug substance development teams by providing experimental results, technical updates, documentation, data interpretation, recommendations, etc.
  • Work cross-functionally to deliver regulatory documents and support regulatory filings
  • Serve as a technical expert and keep current in the field of organic and process chemistry
  • Work effectively in a multi-disciplinary team of chemists, engineers, and attribute scientists
  • Work independently in advancing projects and studies within required deadlines
Requirements
  • Doctorate degree in Chemistry completed by June 2025 OR
  • Master's degree in Chemistry and 4 years of industry experience OR
  • Bachelor's degree in Chemistry and 6 years of industry experience
Preferred Qualifications
  • PhD in organic chemistry with a specialization in total synthesis, reaction methodology, mechanistic studies, biocatalysis, peptide chemistry, oligonucleotide chemistry, conjugation chemistry, and/or chemoinformatics/machine learning
  • Post-doctoral experience in an academic laboratory or pharmaceutical/biotech industry
  • Track record of peer-reviewed publications and research presentations
  • Demonstrated ability to work within a dynamic and interdisciplinary environment to achieve results
  • Excellent written and verbal communication skills, ability to multitask, effectively plan, and follow through on complex projects


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