Research Scientist, Liver Disease Researcher
4 weeks ago
We are seeking a highly skilled Research Scientist to join our team focused on the validation of novel targets and the evaluation of drug candidates for the treatment of chronic fibroinflammatory liver diseases.
As a Research Scientist, you will apply your expertise in executing in vitro studies relevant to fibroinflammatory liver disease biology and pharmacology. You will play a central role in generating key data for evaluating potential targets, mechanism of action, and/or drug candidate efficacy and pharmacodynamics.
Key Responsibilities:
- Design and execute relevant target and drug candidate validation studies using contemporary methods and tools.
- Determine mechanism of action for drug targets and candidates with appropriate controls.
- Implement target-specific assays to assess target and drug activity in vitro and/or in vivo, as appropriate.
- Identify orthogonal applications of target, pathway, or platform biology in other fibroinflammatory diseases.
- Participate on cross-functional teams and provide technical leadership in area of expertise.
- Prepare technical reports, summaries, protocols, and quantitative analyses in written and/or oral form.
Requirements:
- PhD degree in a scientific discipline (or equivalent), or MS with 6+ years relevant experience, or BS with 8+ years relevant experience in vitro drug discovery research.
- Demonstrated ability to independently solve scientific problems using multiple, state-of-the-art technologies and approaches.
- Significant experience with drug discovery applications of cell culture, including immortalized cell lines, primary cell cultures, and multicellular or organoid culture models.
- Expertise in at least one of the following assay methods: ELISA, Western blot, qPCR, flow cytometry, ChIP.
- Experience and continued willingness to work with live rodents and animal tissue.
Takeda is committed to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information, or characteristics protected by law.
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