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Clinical Laboratory Specialist

2 months ago

Waltham, Massachusetts, United States BostonGene Full time
About BostonGene

BostonGene Corporation is a pioneering biotechnology company that specializes in the development of advanced biomedical software for personalized therapy decision-making in the fight against cancer. Our mission is to enable physicians to provide every patient with the highest probability of survival through optimal cancer treatments using advanced, personalized therapies via sophisticated analytics and the integration of scientific and clinical knowledge.

Job Summary

The Clinical Laboratory Technologist will be responsible for performing high-complexity molecular testing according to established Standard Operating Procedures (SOPs), including DNA and RNA extractions, NGS library preparation, hybridization-based enrichments, and next-generation sequencing.

Key Responsibilities
  • Operate and maintain quantification, sizing, liquid handling, and NGS instruments under supervision.
  • Perform daily, weekly, monthly, and as-needed equipment maintenance checks to ensure optimal performance.
  • Order and maintain adequate supplies of all reagents and consumables to support laboratory operations.
  • Participate in reagent and assay quality control and validations to ensure accuracy and reliability.
  • Demonstrate commitment to quality and continuous improvement in all aspects of laboratory operations.
  • Develop and implement workflow processes that maintain quality, thoroughness, and optimum efficiency for Turn Around Time (TAT).
  • Utilize the Laboratory Information Management System (LIMS) to track and execute sample processing, ensuring accurate and timely results.
  • Document and maintain records and data for executed process steps per Good Documentation Practices (GDP).
  • Participate in additional continuous quality improvement activities to enhance laboratory operations and patient care.
  • Adhere to safety protocols, including wearing laboratory coats and required safety gear, to ensure a safe working environment.
  • Maintain organization and cleanliness in the laboratories to ensure a productive and efficient work environment.
  • Collaborate with colleagues to revise and update Standard Operating Procedures (SOPs) as needed to reflect process improvements and regulatory changes.
  • Contribute to quality improvement initiatives to enhance laboratory operations and patient care.
  • Support planning and execution of process development and improvement activities, including LIMS and automation projects.
  • Collaborate with colleagues to update SOPs and ensure compliance with regulatory requirements.
  • Develop a close working relationship with technical and scientific staff to ensure effective collaboration and communication.
Qualifications
  • 2+ years of relevant laboratory experience in a CLIA/CAP laboratory.
  • Working knowledge in a NGS (Next-Generation Sequencing) environment.
  • Bachelor of Science (BS) in Biological or Life Sciences.
  • Experience with ensuring and maintaining integrity and quality of the laboratory (sample processing, equipment, SOPs).
  • Ability to learn new tasks in appropriate timeframes.
  • Excellent attention to detail with experience following precise instructions.
  • Well-organized.
  • Excellent communication skills.
  • Proficiency in Laboratory Information Management System (LIMS).
  • Knowledge of laboratory safety protocols.