Cancer Genomics Scientist

2 days ago

Seattle, Washington, United States Fred Hutchinson Cancer Center Full time

About the Role

This role is perfect for individuals who want to make a meaningful impact in the fight against cancer. As a Bioinformatics Analyst, you will have the opportunity to work with cutting-edge technologies and collaborate with top researchers in the field.

Key Responsibilities

  • Bioinformatics Analyst I:
    • Apply computational and analytical approaches to study genetics and epigenetics of cancer from tumor and liquid biopsies.
    • Run established bioinformatic tools and pipelines for analysis of normal and cancer 'omics' datasets.
    • Collaborate with research team to document, process, manage, and store large datasets.
    • Generate figures and tables summarizing data outputs.
  • Bioinformatics Analyst II:
    • Analyze cancer genomes to understand tumor progression/evolution/heterogeneity, metastatic disease, non-coding genome alterations, copy number alterations, genome rearrangements, and 3D structure, mutational signatures.
    • Partner with Fred Hutch scientists to refine computational research questions and design analytical processes that can be applied to these genomic datasets.
    • Develop and/or apply machine learning techniques to analyze large cancer datasets.
    • Identify and implement appropriate bioinformatic tools for analyzing sequence data from tumor genomes including long-range sequencing technologies (linked-reads, long-reads, optical mapping).
    • Develop and implement computational approaches to analyze circulating tumor DNA from liquid biopsies.
    • Prepare figures and written sections to document methods and results for manuscripts, presentations, and grant applications.
    • Implement and maintain best practices in large-scale data management and database development.

About the Team

You will be part of our dynamic Computational Biology Program, working alongside experienced researchers and experts in the field. Our team is committed to advancing cancer research and improving patient outcomes through innovative computational approaches.

Requirements

  • Bioinformatics Analyst I:
    • Minimum 1 year experience with analyzing genome sequencing data.
    • Strong programming skills in R and Python.
    • Prior experience working with cancer genomics datasets preferred.
    • A background in cancer biology preferred.
    • Experience working in and developing workflows for cloud computing environments preferred.
    • Experience with high performance computing environments preferred.
    • Strong skills in implementation of analytical tools at scale preferred.
  • Bioinformatics Analyst II:
    • Minimum 3 years relevant experience, or a master's degree with a minimum 1 full year of relevant experience outside the degree requirements.
    • Effective use of shell scripting and significant fluency in R and Python 3.
    • Familiarity with workflow and scheduling software (e.g., Slurm) preferred.

Salary Range

The annual base salary range for this position is $68,162 - $102,211 for Bioinformatics Analyst I and $78,894 - $118,310 for Bioinformatics Analyst II, depending on experience and qualifications.

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