Scientific Researcher

1 week ago


Ridgefield, Connecticut, United States Fladger Assoc. Inc. Full time

Job Summary:

We are seeking a highly motivated and experienced Scientist III/IV to join our team at Fladger Assoc. Inc.

About the Job:

This is an excellent employment opportunity for a Scientist III/IV in Ridgefield, CT area. As a key member of our research team, you will be responsible for developing and executing in vivo studies to qualify exploratory new therapeutic concepts for anti-inflammatory and/or fibrotic mechanisms.

You will contribute to the incorporation of new ideas and the development of innovative processes, including technologies such as in vivo siRNA and adeno-associated virus (AAV) delivery. Additionally, you will independently plan, coordinate, conduct, and interpret non-routine in vivo studies to explore mechanism of action and biomarker identification, to support translational biology and deliver clear understanding of new therapeutic concepts.

The ideal candidate will have strong analytical and problem-solving skills with proven track record of high research accountability and productivity both independently, with minimal supervision and within a team setting in a matrix environment. You must also have excellent verbal, presentation, and written communication skills, with the ability to propose, articulate, evaluate, and defend scientific ideas and data.

Requirements:

To be successful in this role, you will need to have:

  • A Bachelor's Degree up to a PhD from an accredited institution with 3+ years' experience in Immunology or a related field
  • Understanding of basic Scientific principles and research practices in the field of Immunology
  • Strong understanding of mouse biology and immunology with extensive hands-on experience conducting rodent experiments including preparation of test compounds, handling and dosing mice by various routes (IP, SC, IV or PO), collection of blood and tissues for PK and PD biomarker analysis
  • Experience in techniques such as ELISA, MSD multiplexing, RNA isolation, RT-PCR and western blots
  • Experience in using multi-color flow cytometry (FACS) to evaluate immune cell biomarkers and data analysis software is preferred but not required
  • Experience or familiarity with in vivo vector delivery (e.g., minicircle DNA, adeno-associated virus (AAV) or si/shRNA) is preferred but not required
  • Familiarity with hydrodynamic tail vein injection is a plus but not required
  • Experience in use of Microsoft Office tools and GraphPad (Prism)
  • Team player with exceptional verbal, presentation, and written communication skills

Salary: The estimated salary for this position is $120,000 - $180,000 per year, depending on experience.

About Us:

Fladger Assoc. Inc. is a leading research organization dedicated to advancing the field of Immunology. We offer a dynamic and collaborative work environment, with opportunities for professional growth and development.



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