Production Manager Oligosynth

3 days ago


San Carlos, California, United States Elegen Full time
Unlock the Potential of Programmable Biology

Elegen is revolutionizing the biology-based economy with a groundbreaking approach to DNA synthesis, delivering unparalleled lengths and accuracy. Our multidisciplinary team of experts applies cutting-edge technologies to solve critical bottlenecks in synthetic biology workflows, empowering our customers in pharma, biotech, agbio, and biomanufacturing to streamline their work and realize the full potential of programmable biology.

Key Responsibilities:
  • Lead and Manage Production Operations: Collaborate with the R&D team to implement new processes, set throughput, cost, and quality goals, and optimize production processes.
  • Timely Manufacturing of Oligo: Manage and execute batches in the lab to ensure timely manufacturing of oligo, coordinate with relevant teams to optimize efficiency, and meet production targets.
  • Quality Control Inspection: Perform QC of incoming raw material, ensure they meet specifications, conduct QC of molecular kits, interpret and respond to validation data, and ensure production outputs meet all specifications for high-quality reagents.
  • Data Analysis: Perform preliminary analysis of production data, build dashboards and KPIs, and maintain a detailed laboratory notebook for batch records.
  • Process Improvements: Collaborate with the Process Development and Research and Development teams to drive process improvements.
  • Software Development: Develop a LIMS for daily production execution and enhance features over time to meet production needs, while actively participating in end-user validation for software support.
  • Team Management: Hire and manage a small team of production associates, provide guidance, training, and support as needed, ensure effective communication, teamwork, and adherence to safety and quality standards.
  • Troubleshooting and Weekend Support: Provide troubleshooting assistance to address production issues and offer support over the weekend to maintain production continuity and resolve urgent matters.
Requirements:
  • Bachelor's degree in a relevant field (such as Molecular Biology, Biotechnology, Chemical Engineering, or a related discipline)
  • 3+ years of experience as production/manufacturing lead in oligo synthesis within life sciences
  • Strong knowledge and working experience with HMI and GUI
  • Experience with lab automation, liquid handling robots, oligo synthesizer, and performing instruments maintenance
  • Experience with new product implementation, operational scaling, and training operators
  • Experience working with hazardous substances and PPE
  • Strong problem-solving and troubleshooting skills
  • Data tracking and managing via LIMS, Excel, and Google Sheets
Preferred Qualifications:
  • Proven ability to manage production batches and personnel schedules effectively
  • Experience in managing reagent and bead preparation, as well as bead loading into the microfluidic chip
  • Ability to lift and move objects of 50lbs
  • Support lab execution preliminary
  • Experience in data analysis, reporting, and presentation
  • Excellent collaboration and communication skills to work effectively with cross-functional teams
  • Previous experience in managing a team
  • Availability to provide support over the weekend


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