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In Vitro Research Scientist
2 months ago
At Eli Lilly, we combine compassion with innovation to enhance the quality of life for individuals globally. As a leading healthcare organization, our headquarters are located in Indianapolis, Indiana, and our dedicated workforce strives to discover and deliver transformative medicines to those in need, enhance disease understanding and management, and contribute to our communities through philanthropy and volunteer efforts. We prioritize our commitment to excellence and place people at the forefront of our mission. We seek individuals who are passionate about improving lives worldwide.
The Diabetes, Obesity, and Complications Therapeutic Area (DOCTA) at Eli Lilly and Company is dedicated to the discovery of biological, small molecule, and genetic therapies aimed at treating diabetes, obesity, and related complications. We are in search of a talented and driven in vitro research scientist to join our drug discovery and development team within the Dyslipidemia and New Modality research group in Indianapolis. The ideal candidate will leverage robust molecular and cellular biology expertise to initiate discovery projects and support our pipeline initiatives. The primary focus will be on therapeutics addressing obesity, metabolic disorders, and dyslipidemia. Extensive experience in developing and executing in vitro and cellular assays is essential. Responsibilities will include establishing vital laboratory capabilities and collaborating with scientists across various departments to meet project and departmental objectives.
Do you possess a strong background in cellular and molecular biology? We invite you to explore this opportunity with the Eli Lilly team.
Key Responsibilities- Design and conduct in vitro and cell-based experiments autonomously. Assist in the preclinical characterization and assessment of relevant targets and pathways utilizing CRISPR technologies.
- Perform molecular and biochemical evaluations on samples derived from tissues and cells, including RNA/gDNA isolation and analysis, gene and protein expression assessments, and other analytical methodologies.
- Exhibit the capability to work independently with a high degree of ownership and accountability. Demonstrate initiative and a proven track record of success within cross-functional project teams.
- Adapt to new challenges, showcasing the ability to establish novel techniques, acquire new biological knowledge, and swiftly adjust in a data-driven environment.
- Bachelor's or Master's degree with a minimum of 5 years of relevant experience.
- Proven experience in cellular and molecular biology and in vitro assay development within the pharmaceutical sector.
- Expertise in a diverse range of cell biology techniques, including cell culture, transfection, FACS, and various cell-based assays.
- Knowledge and hands-on experience in the implementation of gene editing methods and analysis, including gDNA/RNA isolation, sequencing (Sanger, NGS, long-read), gene expression (qPCR), ddPCR, and protein expression (western, JESS, ELISA, MSD).
- A background in the cell/molecular biology of obesity, metabolic disorders, and dyslipidemia is advantageous.
- Experience with complex cell culture systems, primary culture, co-culture, and stable cell line generation.
- Familiarity with various assay detection technologies (fluorescence, luminescence, FRET, alpha-screen, radiometric assays) and the ability to implement and validate new technologies.
- Support the introduction of new assay technologies.
Eli Lilly and Company is committed to ensuring equal employment opportunities for individuals with disabilities and providing accommodations as needed. We are an EEO/Affirmative Action Employer and do not discriminate based on age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer robust support networks for their members and assist our organization in cultivating talented individuals for future leadership roles.
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