Research Scientist

4 days ago

Camden, New Jersey, United States Coriell Institute for Medical Research Full time

The Coriell Institute for Medical Research is a leading non-profit research institute dedicated to improving human health through biomedical research. As a Research Technician III, you will play a critical role in advancing our mission to innovate in the areas of stem cell research, genome editing, and biobanking.

This position offers a unique opportunity to contribute to cutting-edge research, oversee laboratory operations, mentor research technicians, and promote a culture of collaboration and scientific rigor. The ideal candidate will possess strong leadership, laboratory management, problem-solving, and teamwork skills to ensure high productivity and precision in the lab.

Key Responsibilities:

  • Leadership & Oversight: Lead and support research technicians by overseeing day-to-day laboratory activities, mentoring team members, and ensuring adherence to safety and quality protocols.
  • iPSC Reprogramming: Reprogram primary human cell lines into iPSCs, ensuring adherence to best practices and high-quality standards.
  • Cell Line Management: Perform routine maintenance, expansion, and cryopreservation of various human cell lines. This includes documenting cell culture processes and ensuring traceability.
  • Characterization & Quality Control: Utilize a range of techniques (such as immunohistochemistry, flow cytometry, and qPCR) to characterize iPSC and differentiated cell lines, ensuring consistency and reproducibility in experimental data.
  • Flow Cytometry: Plan, execute, and analyze flow cytometry experiments to characterize cell surface markers and evaluate the quality and purity of iPSCs and differentiated cell types.
  • CRISPR-Cas9 Genome Editing: Execute precise CRISPR-Cas9 protocols for genome modification, contributing to the creation of isogenic cell lines.
  • Laboratory Recordkeeping: Maintain detailed, accurate, and up-to-date laboratory records, ensuring all data are traceable and can be used in future projects and publications.
  • Inventory & Reagent Management: Oversee the maintenance and organization of lab inventories, reagents, media, and various instruments.

Qualifications:

  • Master's or Ph.D. degree in Cell/Molecular Biology, Biotechnology, or a related field.
  • Minimum of 5 years of hands-on experience with iPSCs and human cell lines.
  • Strong working knowledge of molecular and cell biology techniques, including ELISA, qPCR, DNA/RNA isolation, immunohistochemistry, and flow cytometry.
  • Experience or familiarity with biobanking practices and cellular quality control standards.
  • Proven leadership and laboratory management experience, with the ability to mentor and guide research technicians.
  • Exceptional attention to detail, analytical skills, and ability to manage multiple projects in a dynamic research environment.
  • Meticulous recordkeeping and organizational skills, with a commitment to maintaining laboratory and biobank best practices.

We offer a competitive salary of $85,000 - $105,000 per year, depending on experience, as well as a comprehensive benefits package. If you are a motivated and highly skilled individual with a passion for biomedical research, we encourage you to apply.

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