Senior ADME Scientist

2 weeks ago

Marquand, Missouri, United States BioSpace, Inc. Full time
Job Summary

We are seeking a highly skilled and experienced ADME scientist to lead and innovate in a multidisciplinary team environment. The successful candidate will have a strong background in ADME-PK properties of large molecule therapeutics and a keen ability to derive and efficiently test ADME and DMPK hypotheses.

Key Responsibilities
  • Design and implement hypothesis-driven studies to answer ADME PK/PD and clinical pharmacology questions.
  • Integrate ADME, PK, and PK/PD endpoints with discovery biology data to define structure-activity- and structure-property-relationships to guide drug delivery and optimization strategies.
  • Critically evaluate integrated data packages and in due diligence of assets for developability assessment.
  • Lead the preparation of regulatory communication and documents to support clinical development (IND), new drug applications (NDA), and BLA and line extensions and interact with regulatory agencies worldwide.
  • Build and foster relationships through coaching and mentorship with fellow scientists.
Requirements
  • Ph.D. in Biochemistry/Biology/Cell Biology/Pharmacokinetics or a related scientific field.
  • 5+ years of experience in the industrial discovery and development of large molecule therapeutics.
Preferred Skills
  • Industry experience with PK/PD modeling of bio-therapeutics.
  • Understanding of and experience with immunoassay and/or LC/MS bioanalytical methodology.
  • Detailed understanding of pharmacokinetics, ADME, and proficiency to communicate theory and concepts clearly.
  • Ability to balance multiple projects and handle competing responsibilities.
  • Demonstrate strong communication skills with the ability to integrate diverse perspectives, deliver critical messaging, and influence leaders/key partners.
About Lilly

Lilly is a global healthcare leader headquartered in Indianapolis, Indiana. We are dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. We are an EEO/Affirmative Action Employer and do not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability, or any other legally protected status.

We offer a range of employee resource groups (ERGs) that provide strong support networks for our members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ+ Allies), Veterans Leadership Network, Women's Network, Working and Living with Disabilities. Learn more about all of our groups.

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