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Cleveland, Ohio, United States Actalent Full time{"Job Title": "Research Scientist", "Job Description": "Actalent is seeking a highly skilled Research Scientist to work in our R&D facility in Cleveland, Ohio. As a Research Scientist, you will be responsible for formulating mixtures from raw ingredients, preparing and painting panels, and formulating paints. You will need to lift up to 5 gallons and handle...
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Research Scientist Position
2 months ago
Cleveland Clinic is seeking a highly motivated Postdoctoral Research Fellow to join our team in the Department of Inflammation and Immunity. The successful candidate will be engaged in high-impact translational research, contributing to a deeper understanding of Primary Sclerosing Cholangitis (PSC) and its associated risks.
Research FocusThe selected applicant will join the Awoniyi lab, which is at the forefront of investigating the role of the gut microbiome in PSC and its correlation with Inflammatory Bowel Disease (IBD), as well as the predisposition to hepatobiliary and colorectal cancer. Our research strategy integrates patient-derived clinical data with in vitro and in vivo experimental models, aiming to:
- Explore the therapeutic potential of microbial strains in PSC, aiming to identify bacteria that may mitigate disease symptoms or modify its course.
- Investigate the microbial driven therapeutic and pathogenic mechanisms of colitis-associated colorectal dysplasia in PSC-IBD models, examining microbial, intestinal mucosa and biliary contributors to disease progression.
- Assess the effects of fecal microbial transplants from PSC patients on biliary health in germ-free mice, to understand the microbiome's influence on disease development.
The Postdoctoral Research Fellow will be responsible for:
- Independent project design with the goal of data generation, analysis, interpretation and manuscript preparation.
- Designing and conducting experiments.
- Analyzing data and preparing manuscripts for peer-reviewed journals.
- Disseminating findings via conference presentations and scientific publications.
- Collaborating within multidisciplinary teams to expand the scope of research.
The ideal candidate will have:
- Completed a terminal degree (D.V.M., M.D., Ph.D.) in a relevant scientific discipline such as hepatology, biochemistry, immunology, microbiology, or molecular biology.
- An established track record of research excellence as evidenced by peer-reviewed publications.
- Proficiency in English and strong communication skills.
- Prior experience with rodent models of liver disease is advantageous, but not required.
Cleveland Clinic offers a competitive salary and benefits package, as well as opportunities for professional growth and development. We are committed to principles of diversity and are proud to be an equal opportunity employer.
